Brain-Gut Health Initiative Supports AI-Assisted Diagnosis of Psychiatric Disorders
Chinese researchers launched the Brain‑Gut Health Initiative (BIGHI), a prospective cohort of more than 1,200 adults with schizophrenia, depression, bipolar disorder and healthy controls. The study integrates neuroimaging, EEG, blood panels, and gut‑microbiome sequencing to uncover multi‑system biomarkers. Early results show EEG microstate patterns and MRI‑based AI models can distinguish patients and predict treatment response, while specific microbial shifts link to symptom severity and cognitive performance. The integrated analysis also suggests accelerated biological aging in schizophrenia, highlighting the potential for AI‑driven, biomarker‑guided diagnostics and personalized therapies.
For a Brief Moment, You Know Them as Kids
The author recounts a recent family crisis when his youngest son faced a possible brain surgery, later diagnosed as treatable pseudotumor cerebri. Instead of a sterile hospital stay, the family turned the trip into a "mercy trip," visiting the zoo...
AI Helps Chemists Design Molecules Step by Step
Researchers at EPFL unveiled Synthegy, a new framework that pairs large language models with traditional retrosynthesis and mechanism‑prediction tools. By translating candidate pathways into text, the LLM evaluates each route against plain‑language user goals and scores its chemical plausibility. In...
Modular Design Takes Center Stage at Palazzo Acerbi
SHAPE SHIFT An epic play on modularity at Palazzo Acerbi for my show with H&M Home. The Soluna Lounge Chair and Poma Accent Chair from my collaboration with H&M Home arranged and rearranged, scaled and grouped, showing every way these...
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Experts Say These 9 Superfoods Can Help You Live a Longer, Healthier Life
A team of registered dietitians identifies nine superfoods—kimchi, turmeric, blueberries, avocado, spinach, kale, lentils, chia seeds, and tempeh—that contain antioxidants, fiber, healthy fats, and micronutrients linked to reduced inflammation and chronic disease risk. The experts explain how each food supports...
Scarlett Johansson’s Oscar-Winning Hit Is Coming To Peacock
Taika Waititi’s Oscar‑winning black comedy *Jojo Rabbit* will debut on Peacock on May 1, 2026. The 2019 film, starring Scarlett Johansson and Roman Griffin Davis, earned roughly $90 million worldwide against a $14 million budget and garnered critical acclaim. It received six Academy Award...
Maggie Rose Joins Gov’t Mule in Alabama
Gov't Mule’s spring tour stopped in Albertville, Alabama, where country‑rock singer Maggie Rose opened the show, marking a rare one‑off pairing after a week with Larkin Poe. The quartet delivered a marathon set that opened with a Tom Waits cover,...
From Rule of Thumb to Mechanistic Formula: An AI-Assisted Model for Individualizing Shuttle Run Distance in HIIT
A new AI‑assisted mechanistic formula replaces the long‑standing 0.7‑second rule for adjusting shuttle‑run distance in high‑intensity intermittent training (HIIT). The model computes time lost per change of direction (COD) as t_cod = v / A0, where A0 reflects each athlete’s acceleration and deceleration capacity,...
Study Finds Different Types of Crystalloid Fluids Are Equally Effective for Pediatric Sepsis
A multinational trial involving more than 9,000 children with suspected septic shock found that balanced crystalloid fluids and 0.9% saline are equally effective at preventing major adverse kidney events within 30 days. MAKE30 occurred in 3.4% of the balanced‑fluid group...
Why Your Steak Isn't Browning On The Grill
Grilling a steak without a brown crust is usually caused by excess moisture, low‑temperature oil, or insufficient heat. Removing surface water, using a high‑smoke‑point fat such as peanut or safflower oil, and maintaining grill temperatures between 450 °F and 550 °F restores...
Queens of the Stone Age Perform with Nick Oliveri for First Time in 12 Years: Watch
Queens of the Stone Age reunited with former bassist and vocalist Nick Oliveri for the first time in 12 years during a Joshua Tree, California show on April 24. Oliveri joined frontman Josh Homme on stage to sing the Rated R...
Platelet-to-HDL Ratio Linked to Eosinophils in Pediatric Asthma
A new study in Pediatric Research reveals a positive correlation between the platelet‑to‑HDL cholesterol ratio (PHR) and blood eosinophil counts in children with asthma. Analyzing a well‑characterized pediatric cohort, researchers found that higher PHR values align with elevated eosinophils, indicating...
Start Building Something to Find Direction and Purpose
If you feel lost, build something. A business. Your body. A skill set. Anything that gives you a reason to learn and focus. Don't worry about choosing the right thing. Don't think about how difficult it will be. Just start moving forward and...
"Thinkhaven"
Thinkhaven is a proposed intensive writing program designed to train participants to generate novel, useful ideas daily. Participants must publish a 500‑word research journal each day, embed at least one new question, and produce a 2,500‑word effort post every two...
Renewables Dominate Future Grids; Nuclear's Role Marginal
New paper: "Perspectives on nuclear power" Systems with renewable energy, storage, and demand response dominate least-cost future energy system options under realistic conditions. New nuclear contributes only marginally. Past studies of nuclear exaggerated its role by using unrealistically low overnight capital...
10 Minutes Backstage with Bailey Zimmerman at Stagecoach
Country‑rock singer Bailey Zimmerman delivered a high‑energy set at Stagecoach, blending original hits like “Religiously” with a Miley Cyrus cover and a duet featuring BigXthaPlug. In a backstage interview he highlighted his fourth straight appearance at the festival and detailed his...
Gentle Techniques to Activate Your Nervous System and Break Free From Stagnation
Feeling stuck often signals an underactive or overwhelmed nervous system. The article outlines gentle, mindful practices—breathing exercises, low‑impact movement, sensory touch, and grounding—to safely stimulate the sympathetic and parasympathetic pathways. These techniques aim to restore energy, clarity, and emotional regulation...
Bring On the Lousy Airport Lounges
Benjy Harmon argues that even sub‑par airport lounges can be valuable, emphasizing that basic comforts—seat, beverage, and a place to read—make them worthwhile for moderate travelers. He frames lounge exploration as a points‑driven hobby, where curiosity leads to hidden gems...
Invest in Mentors to Accelerate Your Growth
If you want to make rapid progress, pay to learn from people ahead of you. Almost always the highest-return investment you can make. Every “power level” came immediately after I made an uncomfortably large investment in myself. The problems and...
Severe Infections Independently Amplify the Risk of Dementia Later in Life
Researchers analyzing Finland’s nationwide health registry found that severe infections requiring hospitalization increase the risk of later‑life dementia. After reviewing up to 21 years of records for 62,555 dementia patients and five matched controls each, they identified cystitis and unspecified...
Windows File Explorer Got so Much Better After I Removed These Extra Sections Completely
Windows 11’s File Explorer now adds Home, Gallery, and OneDrive to the navigation pane by default, cluttering the view. The article explains that these items lack built‑in toggles, so users must edit the registry to hide each section. Detailed steps remove...
On The Up: Moxy the Wellbeing Pony Brings Joy to Children at Hawke’s Bay Hospital
Moxy, a nine‑hand miniature pony, visited the pediatric ward at Hawke’s Bay Hospital as part of end‑of‑life doula Alysha Jayne’s Grief to Peace program. The brief encounter sparked visible emotional lifts, with some children sitting up for the first time...
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Struggling With Money Stress? How Healing Financial Trauma Helps Your Family
Financial trauma—intense anxiety around money—affects roughly one‑quarter of Americans and can echo across generations. Triggers range from the 2008 recession and medical debt to discrimination and divorce, often leading to extreme saving or compulsive spending. Experts recommend introspection, open family...
We Goofed
Yale’s Sterling Memorial Library is hosting “‘Beauties of My Style’: Errata and the Printed Mistake,” an exhibition that spotlights the centuries‑old practice of inserting errata slips into printed books. The show displays early examples, from a 1622 satirical poem to...
From Private Suites to $20,000 Seats: Luxury Travelers Have More Ways to Splurge While Many Passengers Can’t Afford Economy
Airlines are reallocating cabin space toward ultra‑premium offerings as affluent travelers spend up to $12,400 per vacation, prompting the rollout of studio suites and private pods that can exceed $9,000‑$20,000 round‑trip. United, Delta, Cathay Pacific and Qantas are redesigning aircraft,...
Untitled
NASA’s Dark Energy Spectroscopic Instrument (DESI) has completed its five‑year survey, cataloguing over 47 million galaxies and quasars to produce a three‑dimensional map of the universe extending 11 billion light‑years. The map, featured in today’s Astronomy Picture of the Day, shows the...
Three on a Theme: Works of (Auto)biography by Susie Boyt, Sarah Laing and Jenn Shapland
The article reviews three memoir‑biography hybrids—Susie Boyt’s *My Judy Garland Life*, Sarah Laing’s *Mansfield and Me*, and Jenn Shapland’s *My Autobiography of Carson McCullers*. Each author uses an iconic woman—Garland, Mansfield, McCullers—as a lens to examine personal trauma, sexuality, and creative identity....
Ultra-Processed Foods Linked to Measurable Drops in Human Attention Span
A new cross‑sectional study of over 2,100 Australian adults links higher consumption of ultra‑processed foods (UPFs) to measurable declines in attention span, even among those following otherwise healthy diets. Researchers found that a 10 percent increase in UPF intake—roughly one extra...
Free Shipping This Weekend for Indie Bookstore Day
There's free shipping at Bookshop.org this weekend to celebrate Indie Bookstore Day, if you're looking for a new read https://bookshop.org/p/books/metallic-realms-a-novel-lincoln-michel/0a3abce8348fccc4?ean=9781668058671&next=t
MASH Cirrhosis Trials Lack Consistent End Points
A new systematic review of phase 2 and 3 trials for metabolic dysfunction‑associated steatohepatitis (MASH) cirrhosis finds that endpoint selection is highly variable, with most studies relying on histologic improvement and few incorporating patient‑centered outcomes. The analysis identified only nine eligible...
Book Review: ‘The Radiant Dark,’ by Alexandra Oliva
Alexandra Oliva’s new novel *The Radiant Dark* imagines an alternate 1980s where humanity finally confirms extraterrestrial life on the exoplanet Ross 128 b, eleven light‑years away. The story follows Carol Girard, a new mother battling undiagnosed postpartum depression, as global attention shifts...
Decoding Alzheimer’s Disease
Alzheimer’s disease research is pivoting away from the long‑standing amyloid hypothesis toward metabolic and immune pathways. Recent studies show that boosting mitochondrial energy can enhance memory in animal models, while systemic immune cells are found infiltrating the cerebrospinal fluid of...
Netflix Is Getting a Stacked List of Anime for Its May Slate — Here’s 5 You Can't Miss
Netflix is bolstering its May 2026 slate with five new anime titles, ranging from returning fan‑favorites to fresh adaptations. The lineup includes Devil May Cry Season 2, One Piece’s Whole Cake Island Part 4 and the start of the Elbaf arc, Jujutsu...
Smoking Behind the Supermarket With You Could Be the Best Rom-Com of 2026
"Smoking Behind the Supermarket With You" is an upcoming anti‑work anime noir set to debut on Crunchyroll in July 2026. Adapted from a Twitter‑originated manga, the series follows over‑worked salaryman Sasaki and teenage cashier Yamada as they bond over smoking...
Contribution to Artemis II Moon Mission Sees Successful Test of a Space Camera Under Cosmic Ray Conditions
The GSI Helmholtzzentrum and FAIR accelerator facility successfully tested a specially modified Nikon Z9 camera under simulated cosmic‑ray conditions in March 2025. Heavy‑ion beams reproduced the high‑energy radiation environment of deep space, confirming the camera’s stable operation. The validated camera was flown...
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Selena Gomez, 33, and Gisele Bündchen, 45, Wear Bras From This Tried-and-True Mall Brand We All Loved as Teens
Victoria’s Secret has re‑entered the mainstream by selling its classic bras on Amazon, with prices beginning around $40. Celebrities such as Selena Gomez and Gisele Bündchen have been spotted wearing the brand’s comfort‑focused styles, from lightly lined wireless bras to the...
Oscar Winner Michael B. Jordan Confirmed for Battlefield Movie
Michael B. Jordan has been confirmed to join the upcoming film adaptation of EA’s multiplayer shooter “Battlefield.” Veteran filmmaker Christopher McQuarrie will write, direct and produce the project, bringing his blockbuster pedigree from the Mission: Impossible series and Top Gun: Maverick. The announcement follows the...
Skepta Releases New EP ‘Más Tiempo Vol. 2’, Says He’s “Adding the Finishing Touches” To “Celebratory” New Album ‘Fork And...
British grime star Skepta has issued the house‑leaning EP ‘Más Tiempo Vol. 2’, a three‑track collection released on his own Más Tiempo label. The EP serves as a prelude to his 23‑week summer residency at Hï Ibiza’s Club Room, where he will...
The Battle of Austerlitz (1960)
Abel Gance’s 1960 epic “The Battle of Austerlitz” revisits the emperor’s career, echoing his 1927 silent masterpiece “Napoleon.” The film showcases vivid Eastmancolor photography by Henri Alekan and a star‑studded French cast, including Claudia Cardinale, Leslie Caron, and a young Jean‑Louis...
When Simple Tasks Overwhelm, Lists Aren’t Enough
Executive function - me: "I'm having trouble doing simple things" the advice: "here's a list of simple things you can do"
Coherent Breathing Beats Meditation for Anxiety Relief
Was only a matter of time until people started going (rightly) crazy about coherent breathing.
CAR Therapies Could Offer New HBV, HIV Treatments
A new systematic review in Frontiers in Medicine evaluates 43 studies of virus‑directed CAR‑T and CAR‑NK therapies for chronic hepatitis B and HIV. Preclinical data show significant reductions in HIV p24 antigen, HBV surface antigen, and viral DNA, while early...
Who Should Be the Next Tech Visionary Biography?
There's the book of: -Naval Ravikant -Elon Musk -Balaji Srinivasan Who would you like to see a book about next? https://t.co/9jozLlCeSJ
Every 1,000 Steps Cuts Mortality Risk by 15%
The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis A 1000-step increment was associated with a 15% decreased risk of all-cause mortality... with significant benefits starting event at 2500/4000 steps/day. https://t.co/8d6VGnP0Dg https://t.co/f9h0D5dWlV
Why some People Feel a Specific Kind of Sadness on Sunday Afternoons that Has Nothing to Do with Monday and...
Sunday afternoon sadness is a widely reported mood dip that occurs in the late‑afternoon, regardless of employment status or age. Researchers argue it stems from childhood weekend routines, when the day’s structure faded and emotional cues like dimming light and...
Falling Battery Costs Enable Storage Paired with Gas
Batteries are a linchpin for unlocking solar and wind energy’s full potential. But the steep drop in costs is now allowing energy-storage technology to be deployed in conjunction with natural gas. Read more: https://t.co/VW5jM3jV6a 📷️: Getty Images https://t.co/y8qGKuzukl
Stunning Wing View Makes Dupont Circle Hotel Unforgettable
Why I’ll Gladly Return To The Dupont Circle Hotel In Washington - View from the Wing https://t.co/0bRbFE0DqU
Alicia Keys Labels Music Industry a “Good Old Boy” Network
Alicia Keys Calls the Music Industry a ‘Good Old Boy Network’, Says Women Are ‘Not Given an Open Door’ https://t.co/Trc6R4TNsA via @variety
Facial Age Acceleration Predicts Earlier Death, Varies by Job
Face photo-based age acceleration predicts all-cause mortality and differs among occupations "We found that face photo-based age predicts all-cause mortality for middle-aged and older individuals meaning that those age faster based on their face photo die sooner." https://t.co/QUUzK4fe9G
Sodium Layer Reveals Ryugu’s Micrometeorite Bombardment History
Japanese researchers think the asteroid Ryugu was once bombarded by micrometeorites. They say the evidence is a thin layer of sodium on the surface of the asteroid's fragments. https://t.co/rK8BrduVX3