Astellas Exercises Option to License Dyno’s AAV Capsid for AI-Designed Gene Delivery
Astellas has exercised its option to license an AI‑engineered adeno‑associated virus (AAV) capsid from Dyno Therapeutics for skeletal muscle gene delivery, marking the first licensed asset from their 2021 partnership. The capsid, created using Dyno’s large‑scale in‑vivo data‑driven AI models, shows enhanced muscle targeting at lower doses, mitigating safety and manufacturing challenges. Under the agreement, Astellas will pay a $15 million upfront license fee and assume all pre‑clinical, clinical and commercialization responsibilities. Dyno will earn milestone payments and royalties on any resulting therapies.
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I’m a Target-Obsessed Shopping Writer—And These 15 Styles Are on My Wish List From the Retailer’s ‘Spring Edit’
Target’s latest “Spring Edit” collection showcases 15 new fashion pieces ranging from dresses to sandals, all priced between $22 and $38. Senior shopping writer Carly Totten highlights standout items such as a $25 tie‑front mini dress, $30 memory‑foam Ada sandals,...
Maple Syrup or Nutella? PM Carney Calls Canadian Artemis Astronaut
Canadian Prime Minister Mark Carney held an Earth‑to‑space call with astronaut Jeremy Hansen, a crew member of NASA’s Artemis II mission and the first non‑American to orbit the Moon. Hansen emphasized teamwork and calculated risk, promising to share images after the...
Kinetic Energy: Seismo by Upsammy & Valentina Magaletti
Upsammy and UK drummer Valentina Magaletti released *Seismo*, an eight‑track album born from a commission by Amsterdam’s Rijksmuseum. The record fuses live mallet percussion with synthesized beats, creating a soundscape that shifts between club energy and ambient textures. Recorded in situ,...
Explora Journeys to Enter Asia-Pacific with 2027 Cruise Itineraries
Explora Journeys, MSC Group’s luxury cruise brand, announced its first Asian itineraries slated for launch in 2027‑2028. The new routes will cover key gateway cities such as Tokyo, Osaka, Shanghai and Ho Chi Minh City, featuring longer port stays and overnight calls....
Multilevel Predictors of Intervention Uptake and Postintervention Physical Activity Behaviors Among Churchgoing Latino Adults
A multilevel, faith‑based physical activity (PA) trial in East Los Angeles tracked 195 Latino adults from 2019‑2025, offering park‑based and online exercise classes. Logistic and linear regressions examined how baseline neighborhood, psychosocial, and sociodemographic factors predicted class attendance and post‑intervention...
Nike’s Cupid-Coded Cortez Is Giving Valentine’s Day in the Spring
Nike has launched a new Polka Dot/Light Magenta version of its iconic Cortez sneaker, featuring a pink upper speckled with red dots and suede accents, priced at $130. The design ties the classic silhouette to a Valentine’s Day‑in‑spring theme, highlighting...
10 Must-Read Books for National Poetry Month 2026
The Academy of American Poets marks the 30th anniversary of National Poetry Month with a curated list of ten books that explore poetry’s intersections with labor, logic, digital community, public life, and climate change. Titles range from Kristin Grogan’s "Stitch, Unstitch,"...
Jamie Dimon Says the Best Teams Work Like Navy SEALs, Not Sprawling ‘Flat’ Corporations
JPMorgan Chase CEO Jamie Dimon urged shareholders to adopt small, mission‑focused teams, likening them to Navy SEAL squads of eight or fewer. He argues that compact groups retain accountability and can act swiftly, contrasting with the ultra‑flat, high‑ratio structures championed...
Review: Helinox Passport Folding Aluminum Trekking Poles
The Helinox Passport TL115 trekking poles are a pair of ultralight, fixed‑length poles that fold to a compact 35 cm length and weigh just 320 g (11.3 oz). Constructed from DAC aluminum alloy, they deliver carbon‑fiber‑level strength while staying well below the weight...
Gorillaz Announce India Debut in January 2027
Gorillaz announced their first-ever Indian performances for January 2027, with shows scheduled in Bengaluru on Jan 23 and Mumbai on Jan 27. The concerts will feature material from their newly released India‑inspired ninth album, The Mountain, which was recorded with local musicians....
Why Pip Edwards Is Backing the Business of Perimenopause
At 39, Australian entrepreneur Pip Edwards experienced the challenges of perimenopause and chose to back Biolae, a new women’s supplement brand, as a shareholder rather than a mere ambassador. Biolae is launching a suite of clinically validated products—including a hot‑flush...
The Most Confident Person in the Room Is Rarely the Most Competent. The Research on This Is Devastating.
The article revisits the classic Dunning‑Kruger studies and shows that the famed over‑confidence of the least skilled is largely a statistical artifact, not a universal cognitive flaw. In reality, most people display a better‑than‑average bias, and confidence is systematically rewarded...
Learn How to Shape Great Staff Volunteering Schemes: Join Our FREE Webinar
edie is hosting a free, live webinar on 29 April 2029 to help senior leaders design credible staff‑volunteering programmes that boost sustainability, ESG and CSR outcomes. Sponsored by Royal Voluntary Service, the 45‑minute session will cover strategic opportunities, programme design, cultural adoption...
Mummified Permian Reptile Reveals Ancient Breathing
A remarkably well‑preserved mummified reptile from the Late Permian, discovered in the Karoo Basin, has provided the first direct evidence of how early amniotes breathed. High‑resolution CT scans reveal a flexible ribcage and a network of air sacs similar to...
The Itch – ‘It’s The Hope That Kills You’ Review: Decadent, Freewheeling Party Underpinned by Genuine Humanity
British duo The Itch released their debut album ‘It’s The Hope That Kills You’ on April 10, 2026 via Fiction Records and I OH YOU. The record fuses nu‑rave, britpop, electro‑punk and art‑rock across ten tracks that oscillate between club...
Renovating Old Floors – An Expert’s Guide to Repairing & Replacing Flooring in a Period House
Renovating floors in period houses balances heritage preservation with modern performance. Early‑era wooden boards often survive with polishing or localized repair, while stone, brick or tile surfaces are usually left intact unless they pose safety risks. Homeowners must weigh the...
RockShox’s New Zeb & Lyrik Vs. The 1500 W Avinox Wave
RockShox unveiled a fully redesigned Zeb and Lyrik fork line, complemented by updated Super Deluxe and Vivid shocks, in a first‑ride podcast episode. The discussion turned to the Avinox M2S motor, which now offers 150 Nm of torque and a 1500 W...
Scientists Discover Spice Synergy that Boosts Anti-Inflammation 100x
Researchers at Tokyo University of Science found that combining three common spice compounds—capsaicin, menthol and 1,8‑cineole—produces an anti‑inflammatory response in macrophages that is several hundred times stronger than any of the agents alone. The synergy stems from simultaneous activation of...
Poland Enters the European Semiconductor Race. Important Agreement with France
Poland’s CEZAMAT research centre has signed a cooperation agreement with France’s state‑owned CEA‑Leti to develop fully depleted silicon‑on‑insulator (FD‑SOI) technology. The partnership joins the European Chips Act pilot‑line network alongside IMEC and Fraunhofer, giving Polish researchers access to world‑class expertise....
Watch Robert Plant Revisit Led Zeppelin’s ‘Ramble On’ on ‘Colbert’
Robert Plant and his backing band Saving Grace appeared on The Late Show with Stephen Colbert to perform a stripped‑down version of Led Zeppelin’s 1969 classic “Ramble On.” The rendition featured an accordion and a theatrical vocal delivery, underscoring the...
Dragonflies and Humans Detect Red Light Using the Same Mechanism
A cross‑species study published in Nature shows that dragonflies and humans detect red light through a shared molecular mechanism involving a conserved opsin protein. Researchers identified that the dragonfly's long‑wavelength photoreceptor uses a G‑protein‑coupled opsin nearly identical to human melanopsin,...
Discipline Isn’t Strength. It’s Trained Attention.
The article reframes discipline as a trainable skill of directed attention rather than a fixed character trait. Neuroscience shows that attentional capacity, not a finite willpower reserve, determines focus performance. Structured cognitive training can rewire neural pathways, boosting attention and...
Robert Plant Performs Led Zeppelin Classic on ‘Late Show’: Watch
Robert Plant appeared on The Late Show with Stephen Colbert on April 8, performing Martha Scanlan’s folk cover “Higher Rock” with his new band Saving Grace and later delivering a rendition of Led Zeppelin’s classic “Ramble On.” The performance highlighted...
Tripodal Carboxylate Bridge Enables Buried Interface Passivation Toward High‐Performance and Durable Perovskite Solar Cells
Researchers introduced nitrilotriacetic acid trisodium (NTANa), a tridentate, non‑planar carboxylate, to simultaneously passivate Sn4+ and Pb2+ defects at the buried SnO2/perovskite interface of perovskite solar cells. The tripodal geometry enables dual‑sided coordination, strengthening electronic coupling and optimizing energy‑level alignment. Devices...
Linen vs Cotton Curtains — Which Material Is Best for Your Window Treatments?
Spring’s brighter days prompt homeowners to swap heavy drapes for lighter window treatments. Designers compare linen and cotton curtains, highlighting linen’s textured weight and dimensional drape versus cotton’s crisp surface and low‑maintenance durability. Both fabrics are breathable, making them suitable...
Hybe India’s Girl Group Auditions Expand to Five International Cities
Hybe India announced a nationwide audition tour to form its first Indian girl group, adding five international cities to the schedule. The auditions will run from early May through late July across ten Indian metros and will also be held...
Unlocking Fast Na+ Transport in Sodium Iron Sulfate Via Coupled Electronic–Ionic Modulation
Researchers have introduced an isovalent Zn substitution at the Fe site of alluaudite‑type sodium iron sulfate, preserving its crystal framework while reshaping the electronic structure. The Zn‑induced redistribution of Fe–O states and site‑specific Na–O coordination lowers the Na+ migration barrier,...
Spectroscopic Signatures of Doping in Thin Films of Semiconducting Single‐Walled Carbon Nanotubes
The review details how chemical, electrochemical and electrostatic doping modifies the optical and Raman signatures of semiconducting single‑walled carbon nanotube (SWCNT) thin films. Doping introduces holes or electrons that shift visible‑to‑far‑infrared absorption, near‑infrared fluorescence, electroluminescence and Raman modes. These spectroscopic...
Ultratough Organic–Inorganic Bicontinuous Network Hydrogel via Crosslinking Liquid‐Like Inorganic Ionic Clusters With Polymer Chains
Researchers have created an ultratough hydrogel by crosslinking liquid‑like calcium‑phosphate clusters with polyvinyl alcohol (PVA) chains, forming an organic‑inorganic bicontinuous network. The resulting PVA/CPC hydrogel exhibits a tensile strength of 32.9 ± 4.7 MPa and a toughness of 108 ± 19 MJ m⁻³, outperforming most high‑performance hydrogels....
A Highly Adhesive Binder Enables Sulfide‐Based All‐Solid‐State Batteries with High Cycling Stability at Low Stack Pressure
Researchers used click chemistry to add hydroxyl groups to a commercial polystyrene‑b‑polybutadiene‑b‑polystyrene (SBS) binder, creating a highly adhesive SBS‑Click binder for sulfide‑based all‑solid‑state lithium‑ion batteries. The modified binder forms hydrogen bonds with both the LiNi0.9Co0.06Mn0.04O2@Li3BO3 cathode and the sulfide electrolyte,...
Dual‐Modified Cellulose Nanofiber Membranes with Boosted Surface Charge for High‐Performance Osmotic Energy Conversion
Researchers introduced a dual‑modified strategy that merges small‑molecule functionalization with polymer grafting to produce cellulose nanofiber membranes bearing opposite, highly amplified surface charges. The enhanced charge and engineered nanochannels boost ion selectivity, delivering power densities up to 5.1 W·m⁻² (negative) and...
NASA’s Private Space Station Program Is Stuck in Procurement Limbo — And the Clock Is Ticking on ISS
NASA’s Commercial Low‑Earth‑Orbit Destinations (CLD) program, intended to replace the aging International Space Station with private stations, has missed its April 2026 award target and still has not issued a final request for proposals. Delays stem from leadership turnover, a...
Cherry Blossom Viewing Starts at Japan Mint in Osaka
The Japan Mint in Osaka opened its gates on April 9 for the annual cherry‑blossom viewing, a tradition dating back to 1883. A 560‑meter promenade now showcases 331 trees of 140 cultivars, including the newly added rare Fukuzakura from Kenrokuen garden....
PVR INOX to Pivot Expansion to 100 Pc FOCO Model over 4 Years
PVR INOX Limited announced a strategic pivot to a 100% FOCO (franchise‑owned, company‑operated) expansion model over the next four years, moving away from its capital‑intensive COCO approach. The company currently runs 1,802 screens and has 71 FOCO screens, adding 12...
Science History: Doctor Hypothesizes that 'Transmissible Proteins' Can Cause Disease, Contradicting a 'Central Dogma' Of Molecular Biology — April 9,...
On April 9, 1982, UC‑San Francisco neurologist Stanley Prusiner published a landmark *Science* paper showing that an infectious protein, later named a prion, caused scrapie in sheep. By demonstrating that the agent lacked nucleic acids and could transmit disease through...
5 Things to Keep in Your UTV Emergency Kit During Hunting Season
Hunters increasingly rely on UTVs and ATVs for season prep, making on‑the‑trail emergencies a real risk. Can‑Am’s off‑road expert recommends a core kit of jumper cables, an air compressor, tire repair supplies, tow straps, duct tape, zip ties, and basic...
Interview: Researching Quantum Algorithms for Today’s Devices
Quantum computers today remain noisy, limiting the number of logical, error‑free qubits despite hardware that can host hundreds of physical qubits. Universal Quantum’s algorithm scientist Lucy Robson is building error‑correction protocols and trapped‑ion algorithms to speed up drug‑discovery simulations, focusing on...
IEC Welfare Connects Crew, Cuts Complaints, and Advocates Offshore Wellbeing
IEC Telecom UAE has rolled out its IEC Welfare System across offshore energy sites, delivering structured satellite connectivity for crew members. The platform supports over 5,000 rotating users each month, cuts user complaints by 85%, and trims troubleshooting time by...
The FDA Has Released Draft Guidance for NAMs Validation – Now What?
On March 18, 2026 the FDA issued draft guidance for validating new approach methodologies (NAMs), including complex in‑vitro models (CIVMs). The guidance centers on four validation principles—context of use, human biological relevance, technical characterization, and fit‑for‑purpose. The 11th 3D Tissue Models Summit in Boston...
Fire Erupts During Test Of The SpaceX Starship V3 Engine
SpaceX experienced a fire during a Texas test of its Starship V3 Raptor engine on April 9, 2026. The incident, captured on a NASA Spaceflight livestream, showed a loud pop followed by a burst of flames on the Raptor North...
I Finally Found a Water Butt for My Garden That's Not a Total Eyesore — And Landscape Designers Say My...
Garden designers are championing rain‑water butts as a practical, eco‑friendly way to water gardens, especially now that hosepipe bans are common. Garden Trading’s new Kingscote 200 L rattan water butt blends a hand‑woven rattan exterior with a recycled‑plastic liner, offering a...
Walk Through History, Dine in Tradition: Your Binondo Experience Starts Here
The Chinatown Museum in Manila’s historic Binondo district opened its Imperial Wing, offering 18 interactive galleries that trace four centuries of Chinese‑Filipino commerce, culture, and community. Admission is now under $3, making the experience accessible to locals and tourists alike....
NASA Artemis II Astronauts Prepare to End Moon Mission in 'Fireball' Re-Entry
NASA’s Artemis II crew completed a historic ten‑day flight, becoming the farthest‑flying humans at roughly 252,000 miles from Earth. The Orion capsule will re‑enter the atmosphere at 23,839 mph, subjecting its heat shield to a high‑risk "fireball" descent. Astronauts held a live press...
Artemis II Is 'Inspiring' A Whole Generation
Artemis II completed a historic crewed lunar fly‑by, the first such mission since Apollo 8, and is now on its return to Earth after a ten‑day journey. The four astronauts—Reid Wiseman, Victor Glover, Christina Koch and Jeremy Hansen—spent more than two years...
Space Mission to Image Earth's Protective Bubble
A first‑of‑its‑kind mission called SMILE will orbit 120,000 km above the North Pole to image Earth’s magnetosphere using X‑ray emissions from solar wind. Led by UCL’s Mullard Space Science Laboratory with partners including ESA, the University of Leicester and the Chinese...
Memorials – All Clouds Bring Not Rain
Memorials, the British duo formed by former Electrelane and Wire members, releases its second album *All Clouds Bring Not Rain*. The record fuses post‑punk, krautrock, and spiritual jazz, delivering cinematic soundscapes anchored by Verity Susman's warm, folk‑adjacent vocals. Critics note the...
'Mini-Brain' Model Explores Concussion's Effects at Cellular Level
University of Cincinnati biomedical engineer Volha Liaudanskaya is using engineered "mini‑brains" to study how concussive forces affect brain cells at the cellular level. The assembloid model combines five cell types—including neurons, astrocytes, microglia and two vascular cells—allowing simultaneous tracking of...
From War to Weather: A 'Super El Niño' Event Poses Fresh Risks to Global Food Costs
A potentially “super El Niño” is forecast for late 2026, raising the risk of severe drought and heat across major agricultural regions. The weather threat compounds already‑high fertilizer and energy prices caused by the Iran‑Hormuz conflict, which has choked roughly one‑third...
Nasa Meteorologists Trialling Model to Produce Ultra Local, Short-Term Forecasts
NASA meteorologists at the Wallops Flight Facility are trialling a new ultra‑high‑resolution weather model called US1k, developed by Meteomatics. The model delivers forecasts on a 1 km grid every 15 minutes, nine times finer than typical operational models. By providing a zoomed‑in...