Vitamin B3 May Undermine Pancreatic Cancer Chemotherapy
Title and header via the @cwru press release: New research reveals dangers of ‘anti-aging’ supplements in cancer protection Vitamin B3 could be making chemotherapy less effective in pancreatic cancer patients https://t.co/vIfcvuiS6P Discussion + thoughtful debate welcome👇👨⚕️ https://t.co/aHewoWeIle
Simple, Restrained Saltimbocca Proves Classic Dishes Belong Back
They don’t make dishes like this anymore… which is exactly why you should. Saltimbocca is what happens when restraint wins. A few ingredients, no showing off, and a result that still outperforms half the menu. Crispy prosciutto. Sage in hot butter. Veal...
NASA Attributes Sensor Reading to Instrumentation, Launch Unaffected
NASA: "Engineers investigated a sensor on the launch abort system’s attitude control motor controller battery that showed a higher temperature than would be expected. It is believed to be an instrumentation issue and will not affect today’s launch."
AI-Driven Biology Could Slash Drug Trial Failures Dramatically
AI for biology will have bigger near term wins. The ability for AI to learn from experiments and predict human biology will have very broad impacts in predicting targets, clinical trials, and precision medicine. Tackling the biggest challenge in Pharma (80%...
Satirical Book Chronicles Year of US Tariff Chaos
In honor of tomorrow's Liberation Day anniversary, I worked with Claude to draft a pretend book about the insane-but-totally-real things that happened over the last year of US "emergency" tariff chaos. Here's the first cut: https://t.co/1srdrUh4Gz
Springsteen Turns Tour Into Full‑Scale Protest Journey
Bruce Springsteen Isn’t Just Doing Protest Songs — With His ‘Land of Hope and Dreams’ Trek, He’s Embarked on a Whole Protest Tour: Concert Review https://t.co/l8kOIG5DLO via @variety
Gravitational Waves Reveal Missing Black Hole Mass Gap
Some stars leave nothing behind. Pair-instability supernovae predict that the most massive stars explode so completely that no black hole remains. For years, we didn’t have evidence. Now, gravitational wave data shows a gap in black hole masses — exactly where those explosions...
Genome Editing Shows Promise for Sickle Cell, Β‑Thalassemia
3 new trial results for genome editing of sickle cell disease and β-thalassemia @NEJM https://t.co/qGGdjgKqP5 (with summary Table below) https://t.co/RdiM3urCKJ https://t.co/W15cPAfMoS https://t.co/F3PHKuktPx https://t.co/t6Z35S8L7h
Endurance Success Depends on Monthly Training Load
For serious endurance athletes, the key loading unit isn’t the training session... It’s the training *month*
Watch NASA’s Live Launch Now via YouTube
If you need it, here's the link to NASA's livestream of the launch. 👇 https://www.youtube.com/live/Tf_UjBMIzNo?si=I5u3hgJLKVNLcv4I
NASA Flags Battery Temperature Issue on Artemis 2 Abort System
NASA reporting an issue with one of the batteries on the Artemis 2 launch abort system; temperature out of range.
Barry O'Reilly Unveils Powerful Concepts in Artificial Organizations
@barryoreilly is on to something powerful with his new book, Artificial Organizations. (available now on Amazon) https://t.co/z6cdROy6pT
Create Your Own Systems or Remain Controlled by Others
This one should hit you hard: If you don’t build your own systems, You’ll live inside systems someone else designed for you.
New Early-Stage Cancer Drugs Emerge at AACR26
A look at some promising early stage drug developments coming down the pike at #AACR26. A few of these concepts were not on the radar a couple of years ago: https://t.co/w6oD4CEckq https://t.co/kfR1AXG41K
Finish First, Stop Buying More Gear
Repeat after me: I will not buy more gear, courses, or books before I finish this project. I have all I need to do this now.
Record Female Life Expectancy Defies Predicted Limits
enjoying this piece on record life expectancy increasing over time - the *insane* linear regression in 1840 - 2010 period just tracking record life expectancy over time (I think trend not consistent since, partic w COVID) - how funny it is that...
Neil Armstrong Marvels at Earth's Fragile Beauty From Moon
Astronaut Neil Armstrong on the beauty of earth as seen from the surface of the moon https://t.co/kT6pCfTzSt
Artemis 2 Launch Window Nears: Range Go, 80% Weather Favorability
A view of Artemis 2 from the KSC press site. Range is go and weather is still 80% favorable for launch during the two-hour window. https://t.co/PdQs3jS1sj
NAD+ Decline Drives Cardiac Aging; NR Restores Rhythm
NAD+ controls circadian rhythmicity during cardiac aging https://t.co/NNVx94IIC8 Fig. 2: Cardiac NAD+ decreases with aging, with restoration by supplementation with nicotinamide riboside. https://t.co/z4uSqKrYjR
Artemis II Launch Paused to Verify Safety System
NASA/Artemis update as of 5pmET: Although the countdown to today’s Artemis II launch is continuing to progress, the Eastern Range has identified an issue that they are currently working to resolve related to their communication with the flight termination system. The...
A Kind of Guise Travels Globally, Capturing National Geographic‑Style Lookbooks
I like how A Kind of Guise shoots their lookbooks in a new country every season. The photos have a National Geographic quality to them. Countries pictured here: Kenya, Mongolia, Albania, and Peru.
Wake Up to Alpine Luxury in the Dolomites
POV: you wake up in the Dolomites to this view… 🏔️✨ Here’s a full tour of my room at ComoAlpinaDolomites, one of the best 5-star hotels in the Italian Alps. Who are you bringing with you? #dolomites #luxurytravel #luxuryhotel #comohotels #wanderlust
Every Pregnancy Is Hormonally Unique to Each Baby
No two pregnancies feel the same, even in the same woman. The cravings change, the nausea changes, your energy changes, your mood changes. Most women notice this but nobody explains why it happens. The placenta is genetically half the baby's father,...
Cosmic Indifference, Human Purpose: Care and Flourish
The fact that the universe doesn’t care about you doesn’t mean that other humans don’t care about you, or that we don’t have to care about other humans. That is, there is a purpose, there is a meaning: that is,...
Debunking Myths: Longevity Science Funding Is Essential
Are you (will you be) in London Wednesday April 8? 👉Arguments against funding longevity science - and why they are all wrong Hosted by London Futurist, my friend (and friend to longevity science) David Wood @dw2 https://t.co/HTj6Xoeu1J https://t.co/13pwYx0ZrU
Finding Hope in Artemis Amid Global Turmoil
I don't know about y'all but I'm absurdly excited about the Artemis mission. Yes, the world is on fire, but this brings me joy.
Shift Your Perspective, Transform What You See
"If you change the way you look at things, the things you look at change." Wayne Dyer 🌺 #WednesdayMotivation #quote #wednesdaythought https://t.co/iJQv7t9uUP
Talent Is Grit, Discipline, Patience, Not Just Gift
Talent matters. But talent has a broad definition. Most of the time, it's not about having a gift, it's about having grit. Discipline is talent. Patience is a talent. Trusting yourself is a talent. Loving the process is talent. —Roger Federer https://t.co/HJqTiH5sci
Change Arrives When Noise Fades, Seize the Wave
Some people do not change when they are most motivated. They change when the noise drops enough for action to become possible. That creates a brief window. A wave 🌊. If they catch it, they can install a new pattern before the...
Focus on One Product, Avoid Spreading Too Thin
"NOOOO yoU SHOuLd FOcUs ON oNE proDuCT yOU CAN'T succEED If YoU SpReaD yoUrSeLf ToO tHiN" Ah yes like Apple, Google and Microsoft did? Right? Right?! https://t.co/0rhB0dwFen
Apollo 8 Saved 1968; Artemis II Hopes to Save 2026
On my first Christmas Eve, Apollo 8 orbited The Moon and ‘saved 1968’. Good luck to Artemis II and may you save 2026! https://t.co/vVNXyenwHG
Kindness Outshines Trolls: Block Negativity with Positivity
Leave with this --> Starve the trolls, amplify the good. Being positive and kind is the ultimate block button on X.
Feeding Swans at Abbotsbury Swannery: A Perfect Day
Abbotsbury Swannery 🦢🤍 Dorset 🦢 A wonderful day out meeting and feeding all of the beautiful Swans 🥰 Thank you abbotsburyswannery for having us 🫶🏻 #dorset #dorsetcoast #daysout #explore #outdoors Ad
Postpartum Fitness Feels Daunting Despite Staying Active
Tbh I’m so nervous for rebuilding my fitness postpartum. I feel incredibly weak and deconditioned despite working out throughout my pregnancy.
Artemis II Countdown Continues Despite Flight Termination Issue
Artemis II update: An issue with the Flight Termination System is being worked, but the countdown is proceeding.
High‑dose Flu Shots Cut Alzheimer Risk, Especially in Women
We've seen the Shingles vaccine is linked with reduced risk of Alzheimer's and dementias in 4 large natural experiments. Today, the potential of high-dose flu vaccines vs standard dose for the same in a large retrospective age 65+ cohort [N>160,000)....
Newborn Sleep Schedule? It's an April Fool's
Trying to follow a new sleep schedule with a newborn is an April Fools Joke
Holding Artemis 1 Panel Returned From Space—Unreal Feeling
I hold an thermal insulation panel from artemis 1 that went to space and come back in my hands thanks to Barry bonhnsack 😄😍 amazing feeling Thank you @youtube @youtubecreators nasa #3dprinting #artemis #nasa #rocket #orion
DIY Hollywood: Pro‑Level Filmmaking Now Cheap
Hollywood might be in trouble. Cinema Studio 3.0 is changing the game. Now, regular people can make big, movie-looking scenes right from their own rooms. Higgsfield Cinema Studio 3.0 comes with about 200,000 visual styles, 150 camera moves, and millions of action-scene...
Year-Long Aerobic Exercise Preserves White Matter, Boosts Cognition
Effects of aerobic exercise and cardiorespiratory fitness on white matter free water fraction in older adults: a 1-year randomized controlled trial "These findings suggest that 1 year of aerobic training may reduce [Free Water Fraction] in the CC body and that higher...
Take a Break: Get Active Outdoors in Colorado
Colorado is built for movement—so whether it’s a walk around your neighborhood, a break between meetings, or time on your favorite trail, I encourage everyone to take a few minutes today to step outside and get active.
Vintage Issey Miyake at My Favorite Mirror Spot
Back at my Favorite place.... in from of my Favorite mirror ❤️❤️❤️ thedominickhotel wearing vintage isseymiyakeofficial
Reject False Choice: Be Intentional with Both Genders
“Over the past few years, we have tried to become more intentional. I think the worst thing we can do is believe in a false choice — that one must sacrifice the other — that you can’t be intentional about...
Next‑Gen AI “Lab‑in‑the‑Loop” Launches Today
For all the great folks advancing medicine and human health through rigorous science + serious applied #AI, here is a next gen “lab in the loop” being released today on 4/1 😜 https://t.co/Li8Bkd9rAQ
Use Duke Professor’s Checklist to Make Better Decisions
How can you improve your decisions? In this Q&A with Duke Prof. Jack Soll, you’ll find a checklist you can use to boost the quality of important choices. https://t.co/K4AXjqBbgN https://t.co/XHtFvj8gL4
IVNS1ABP Mutation Triggers Premature Aging and Neurodegeneration
A mutation in the IVNS1ABP gene causes a new disease combining premature aging and severe neurological decline by disrupting cell scaffolding, leading to DNA damage and “zombie-like” senescent cells. https://t.co/xtDrjy72h4
Mitochondrial Dysfunction Triggers Early Cerebral Amyloidosis
Human in vitro and rodent in vivo models highlight progressive mitochondrial dysfunction as a starting point of cerebral amyloidosis https://t.co/CEfTOeosnu https://t.co/Rd12PlVTAQ
Experts Demand Google Ban AI Videos for Children
Oh boy -> Child development experts have demanded that Google prohibit AI-generated videos from being shown to young viewers on its video platforms YouTube and YouTube Kids, and halt investments in using AI-generated videos for children “This content, riddled with...
Constraints Unlock Decision-Making, Not Unlimited Choice
Our brains just aren’t built for limitless choice. The real unlock? Constraints. You can preorder INSIDE THE BOX now by clicking the link in my bio. https://t.co/bo7CiCnbam
Respect Requires Consistency, Not Bossy Outbursts
You don’t gain respect or compliance from employees by reminding them “you’re the boss” when you’re upset, and then patting their backs after you chewed their head off.