
Discipline, Not Motivation, Drives Real Results
7 days left before the Ultimate Productivity Workshop. Motivation is inconsistent. Discipline is reliable. Guess which one actually gets results? https://t.co/fRVfs3CrbL https://t.co/ipfRWr2sYb

Nourish Body, Mind, and Soul Every Day
What are your plans to nourish yourself today? We can nourish our bodies with food, exercise, sleep+social connection. We can also nourish our minds with good books, empowering self-talk+mental challenges. And we can nourish our souls with volunteer work, reflection+love. #life...

Sodium Needs: Only Ultra-Endurance Runners Require Extra
How much sodium do you really need during exercise? This blog explains when targeted sodium replacement may be necessary, why it mainly applies to ultra endurance events, and why most athletes can simply ‘season to taste’. Click here: https://t.co/eWzOuJjuQQ https://t.co/hVI7pnlsvW
Overworking Steals Time, Energy, and Presence at Home
The real cost of overworking shows up at home where your time energy and presence are no longer there. #worklife #selfcare #mentalhealthtips #therapy #psychology https://t.co/iChucwuYqk
Mother’s Day: Honoring Grief, Absence, and Exhaustion
Mother's Day is complicated for a lot of us. Maybe you're grieving a mother you lost. Maybe you're healing from one who couldn't show up the way you needed. Maybe you're a mother who is running on empty and nobody's checking...
Your Debut Can Be a Later Book, Not the First
Something I wish more debut authors knew: the first book you write doesn't have to be the one that makes your career. 👉 Stephen King wrote 4 novels before Carrie was picked up by Doubleday and became his debut. 👉 Ken Follett...

Goals Need Not Be Perfect—Just Informed Guesses
We talk about goals like they need to be precise, clear, and certain. But most goals start as a guess. They are a guess about what will matter. A guess about what the future might look like. And that’s okay. 👉 You don’t need...
Unlived Potential Breeds Bitterness and Self‑suffering
Quote I’m pondering 🤔: “The world is full of people suffering from the effects of their own unlived life. They become bitter, critical, or rigid, not because the world is cruel to them, but because they have betrayed their own...

ZYME ADC
Catching up with $ZYME pan-RAS inhibitor payload ADCs from #AACR26. Seems the setting for each one is tumours that are RAS-mutated as well as expressing the target antigen (PTK7, Ly6E or Claudin18.2). https://t.co/hljX5soZQi
AI Lets CEOs Choose Focus or Breadth—Which Wins?
With AI tools today, CEOs can either be laser focused, and say no to almost everything (like Jobs) or they can use the tools to do even more, and get involved in everything (like Bezos). Which is better? @dickc talks about...

Collider Ladies Night Drops Major Event Next Week
Next week is gonna be a biggie on the Collider Ladies Night YouTube channel ... https://t.co/1oncxgvbeR

Erin Osmon's New Book Revives 80s Heartland Rock
I wrote about Erin Osmon's new book on 1980s heartland rock, which I heartily recommend. https://t.co/DC16lhE9lF https://t.co/vH2BVNBIwP
Learn Faster: Build, Tackle Roadblocks, Iterate Forever
How to master any skill fast: - stop studying - outline a project - start building it - hit a roadblock - figure out how to overcome it - repeat 4 and 5 for the rest of your life Most people don't get past 1, the rest...
Drop “If” From Goal Talk to Prevent Failure
Stop using the word 'if' when you talk about your goals. 'If I can get this off the ground…' That's the language of someone who's already planning to fail. We don't do that here.

Essential Cycling Tips That Unlock Most of Your Potential
There are a lot of things you can know about cycling training and performance. Then there are certain things you need to know that will bring you most of the way toward your potential. Swipe through ten of them and...
Simple Bedtime Reassurance Turned His Worst Day Around
My son told me said he had the worst day ever. Here's what I said at bedtime that made him beam.
Master the Enrollment Conversation Before Launching New Ventures
Before jumping feet first into the deep end for your next business endeavor, practice having the "enrollment conversation." (The kicker? It's one most of us have never had. 👀): https://lnkd.in/eJmszYDM
Creators' Notebooks Reveal the Messy Path to Greatness
Fascinated by the way notebooks & diaries (while imperfect) can reveal so much about the way great works happens, and the way impactful creators go about their work. Classic eg: "Private Sci of Louis Pasteur." Another: Camus, as discussed @WSJBooks...
AI-Generated Hospitalization Summaries Cut Clerk Workload, Boost Physician Well‑being
Agentic AI summaries of hospitalizations were safe and reduced data clerk burden, burnout, and improved sense of well-being for physicians in a prospective study https://t.co/0nXZ0wjugg
Mortal Kombat 2 Poised for Record Fighting‑Game Opening
WB ready to score its first hit since #WutheringHeights, as R-rated video game adaptation #MortalKombat2 exploded grossing 5.2M on THU Previews including WED fan screenings at US #BoxOffice (vs #Scream5’s 3.5M, #SINNERS’ 4.7M, #AQuietPlace2’s 4.8M, #HalloweenKills 4.9M, #HalloweenEnds 5.4M, #FinalDestinationBloodlines’s...
Transform Your Bedroom to Boost Real Sleep Hours
Your bedroom is either helping you sleep or quietly ruining your life. I wrote about the design changes that actually improve your sleep, what to buy, what to skip, and what to change tonight. Link ⤵️ How many hours of...
TikTok: Musicians' Ultimate Guide to Audience Growth
TikTok is the most powerful music discovery tool ever built. Here's everything you need to know about using it to grow your audience, straight from the musicians who've figured it out. https://t.co/qRVoz0fI6E
Top Gun Returns with Limited‑edition Maverick Popcorn Bucket
Top Gun is coming back to theaters May 13 for one week They’re selling this Maverick popcorn bucket to commemorate the 40-year anniversary https://t.co/kLznOJWlze
Success Demands Relentlessness Over Balance
Most successful people are not balanced. They're relentless. They're fast. They're tough. They're focused. They're less fun. Maybe it doesn't have to be, but it usually is.

Michael Jackson Lands Ten Classics on Hot R&B/Hip‑Hop Chart
Michael Jackson placed 10 songs on Billboard's Hot R&B/Hip-Hop Songs chart this week, including "Billie Jean," "Beat It," "Human Nature," "Smooth Criminal," and "Man in the Mirror." https://t.co/NmESNI7Fg0

Real Supplements That Actually Build Muscle & Recovery
💊Everyone is chasing the perfect supplement stack… but what actually works? Creatine, protein powders, and the supplements that actually build muscle, improve health, and speed up recovery what’s worth it and what’s not? 🎙️Tune in Monday at 9:30 AM CST to...
AI Expert Prioritizes Humanities Over Debt for Kids
Talked to a friend who's one of the smartest people I know on AI & invested in Anthropic: Me: "What do you hope your college-age kids study?" Him: "Nothing that moves them into debt. Ideally humanities. I want them to learn...
Mind over Strategy: Strengthen Your Mental Game
Stop living in fear, stop trading in fear, and make sure your self-talk is strong. Who cares about strategy, technicals, fundamental, etc. if your mind isn't strong. Do everything in your power to make sure your mind is strong.

Wealthy Commuter Chooses Jet over One‑hour Drive
There’s a rich dude that lives near my farm and flies netjets 50 miles back-and-forth to work These two airports are connected by a very nice interstate and the door-to-door drive time is one hour. https://t.co/po0eh1B9l9

V&A Launches Teen Hubs to Revive London Museums
London’s museum scene is in a slump. Now, the city’s institutions are aiming to attract the next generation, with two new outposts of the V&A dedicated to the experiences of teenagers https://t.co/nSIzAHo0or https://t.co/ZQpZQyS8OD

NEJM Publishes Moderna Flu Data After FDA Refusal
A Friday footnote: The New England Journal of Medicine has published the Moderna influenza vaccine data -- the same that led the FDA's CBER division to refuse to review the vaccine under Vinay Prasad. (That decision, called a refuse-to-file or...

Author Rushes to Print “Lithium Confidential” Before Vegas Interview
After “Lithium Confidential” went through the professional editor’s review, I made some changes and sent it to a proofreader. His comment is below. Hopefully the book is printed before @cberry1 interviews me about it in the Live Lounge @Fastmarkets in...

Organ‑Specific Aging Clocks Reveal Multi‑Omics Lifespan Patterns
The big advance in the science of human aging is the ability to quantify it and relate the metrics to health and disease. A new paper today @CellCellPress takes this to the next level with organ clocks and multiple biologic...
Talk About Your Work Daily or Stay Invisible
If you're not talking about your work every day for the next 3 years: You're invisible. And invisible people don't get paid. They don't reach their potential. No matter how good they are.
Unexplained Infertility Is a Diagnostic Shortcut, Not a Mystery
"Unexplained infertility" is the most overused diagnosis in fertility medicine. It almost never means there is no cause. It means the standard panel did not find a cause. Almost every couple we meet at Ferta who was told they had...

Simple Pre‑Run Fuel: Coffee, Yogurt, Blueberries
Pre-workout for my five mile run 🏃♀️ ☕️Black coffee with cinnamon 🫐Greek yogurt + wild blueberries Carbs + little protein + clean caffeine 🔥 https://t.co/I9FkiKHRrG
Boss's $1M Business‑Class Promotion Sparks Employee Frenzy
Passenger Gets $1 Million And A Promotion In Business Class — Now Everyone Wants To Work For That Boss - View from the Wing https://t.co/pTwbKMq3sq
Activate Aerobic System Early to Avoid Stress‑Induced Fatigue
High stress individuals who simply add in down-regulation without ACTIVELY engaging the aerobic system stand to learn a harder lesson. When the cells early default is glycolysis, obviously the aerobic system lags or struggles/mito limitation. If this person doesn’t teach that...

Adelaide's Ozploitation Horror “Penny Lane Is Dead” Trailer Drops
Adelaide Ozploitation Horror Film 'Penny Lane Is Dead' Official Trailer https://t.co/rwbl1m8iuO #horror #PennyLaneIsDead #Australia #MiaKateRussell https://t.co/vpHgfnyJvb
Sheep Detectives Opens Strong, Eyes Low Double‑Digit Weekend
Hugh Jackman's new family mystery #SheepDetectives kicked off opening wknd with solid $1.03M from THU pre-shows + early access previews. Reviews are strong across the board. PG pic hopes to be a Mother's Day option for moms with younger kids. Opening...
Top 40 Radio
it feels like top 40 stations forcefully put "the fate of ophelia" back in heavy rotation immediately after "elizabeth taylor" was chosen as the doa third single
Focus on Skills, Not Endless Opportunity Content
A tip for younger entrepreneurs, don't spend a lot of time consuming "opportunity content" - how to get rich, business ideas and so on Pick a business idea that sounds interesting & valuable and then consume skills-based info to help you...

Psilocybin Shows Promise After Decades of Failed Cocaine Treatments
For 50 years the National Institute on Drug Abuse has spent hundreds of millions of dollars to find an effective cocaine addiction medication. After 100+ molecules & many hundreds of studies nothing has been FDA approved. It's the Holy Grail...

Incomplete Exhale Spikes Stress; Deep Breaths Calm You
Research shows when we don't exhale completely it increases our feeling of stress. Exhale deeply when you need to relax. https://t.co/R17uuKjar5
Most March Russian Starlink Satellites Maneuvering to Operational Orbit
All but one "Russian Starlinks" launched in March showed signs of maneuvers, presumably on their way to operational orbits. Context: https://t.co/aDdeCmCNC9

Daily Social Connections Boost Health and Happiness
Some research indicates that enjoying connection with family, friends or loved ones at least once a day will help us enhance our health and happiness. 🙏 Do you connect with others 6-7 times a week?🤔 More info on social connections here. https://t.co/vhn86P1bJy #health...
Stevie Wonder’s Late‑December Sun Shines Bright
I wrote about Stevie Wonder's "I Can See the Sun in Late December" for @Spin's Deep Cut Friday column this week: https://t.co/wMiFB6f4aY
Name Your Brain's Fear to Stop Catastrophizing
As a health research advisor, here's a simple protocol to stop your brain from catastrophizing: 1. Name what your brain is doing: "What is my brain trying to protect me from right now?"

Metformin's Primary Action Is Gut, Not Liver
Metformin, one of the most commonly prescribed drugs, was thought to work via the liver. Check that. It's primarily through the gut. @NatMetabolism https://t.co/i2CpZip61B https://t.co/bhsI7p7SYx
ADHD Kids Have Hidden Edge for Quick Cooperation
A child psychologist revealed the “unfair advantage” that makes ADHD kids cooperate faster without yelling