Roche Initiates New Elevidys Trial Targeting EU Approval
Roche to launch another Elevidys trial, with eyes on European approval https://t.co/eAANNiihpt via @DrewQJoseph $SRPT

Soyuz‑5 Launch Window Closes Amid Swirling Rumors
The inaugural launch of the new Soyuz-5 launch vehicle approaches the end of its available window without any official news, so I tried to untangle a morass of rumors and hints about the zig-zag path to flight for our subscribers:...
Success Comes From Helping Others Before Asking
“You can get everything in life you want - if you just help enough other people get what they want. Never, EVER ask for a withdrawal before at least five deposits.” Zig Ziglar, Stephen Covey, and the great @TonyRobbins
Kids Carrying Books Signal a Seismic Literacy Shift
cant find words for the number of kids i see walking with a book in there hand. its not world according to garp but a seismic turn
Prioritize Meaningful Conversations and Relationships for Effective Leadership
"If you want to lead well, organize your day around the conversations that matter and the relationships that need attention. That’s what compounds." - Randall Stutman (EP.497) With thanks to @AlphaSenseInc, @CanoeAI, and Ridgeline.

Tart Cherry Juice Speeds Muscle Force Recovery
Tart cherry juice for muscle damage recovery 🍒 This new meta-analysis compiled data from 19 studies (385 participants) which investigated the effects of tart cherry supplementation on muscle damage in athletes 🔍 Here is what they found ⬇️ 💪 Tart cherry juice...
Rethink Endurance Performance with Modern Evidence-Based Strategies
This webinar is about rethinking endurance performance through a broader, more modern, and more evidence-based lens. Join the session with 40% off: https://t.co/FHjGFZjzbF https://t.co/ebr1vO0CYR
Stenting Advances Treatment for Post‑thrombotic Syndrome
Stenting for Post-Thrombotic Syndrome — A Step Forward {Editorial} [Apr 13, 2026] Flumignan & Nakano @NEJM https://t.co/w559CHaTON #NCT03250247 #VTE

Endovascular Therapy Shows Promise for Post‑Thrombotic Syndrome
Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial [Apr 13, 2026] Vedantham et al. for the C-TRACT [Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy] Trial Investigators @NEJM https://t.co/Ayd4Fa0ARl #NCT03250247 #VTE https://t.co/6iD1NUQdgX
Jim Simons' Five Principles for Business and Life Success
The late billionaire trader Jim Simons shares his five principles of success for business and life: https://t.co/isBafKbZVx
Leadership Is an Infinite Game: Keep Innovating Forward
Leadership is an infinite game. The goal is to keep improving, keep innovating, and keep moving forward. Video from ServiceTitan's North Star Summit

Columbia's First Unpowered Landing: A Historic Glide
45 years ago.. April 14, 1981..spacecraft with no engines glided down and touched down like a giant paper airplane on a dry lakebed in California. Space Shuttle Columbia on STS-1, the very first Shuttle mission, coming in hot over Rogers Dry...
Exploring Christian Petzold’s Mirrors No3 in New Vlog
My vlog on Christian Petzold’s Mirrors No3 is up here, please click, watch, share and subscribe: https://t.co/XrYNgqaUj8
Rebuilding Speech: Physical Mechanics Over Synthetic Voices
Most voice AI tries to fake human speech. This robotic mouth tries to rebuild it. That is what makes this so fascinating to me. Instead of relying on text-to-speech software or digital voice models, it recreates speech by copying the physical mechanics of...
AI Floods Book Market, Threatening Human Authorship
AI is starting to reshape the book market at scale. Thousands of AI-written or AI-polished books are now being sold, raising concerns about quality, originality and the erosion of human authorship. It feels familiar. What was once a dystopian idea is quietly...

Hip Flexor Power Drives Sprint Performance
Sprint running is heavily dependent upon the power output that can be generated by the hip flexors and extensors. Read more in the weekly free Patreon article. https://t.co/sbu6sERoiD
Boost Golf Speed with Intent and Reserve Gap
Intent & speed reserve are two crucial concepts for golfers wanting to be faster. Swinging with maximum intent (trying to “kill the ball” or swing as fast as possible) recruits high-threshold motor units and teaches your nervous system to fire faster...

Cherishing Fleeting Moments Before Kids Grow Up
Aunty duties for two days. For two days I am in charge of their homework, tuition, training, playtime and dinner. One day, I’ll look back at this photo and instead of training bags, it will probably be their army bags....
When Nods Hide Misalignment: 5 Warning Signs
5 signs your team isn’t aligned even if they’re all nodding. https://t.co/cO7jegZ7Ou #leadership #employees #management
Artemis II: A True Leap for Mankind?
It was more than one small step for man, but did the Artemis II mission actually represent a leap for mankind? The folks at The London Standard asked me to investigate https://t.co/fvxpEJcBEd
AmazonMGM's Star‑filled Panel Steals Show From Giants
People really raving about the #AmazonMGM panel, saying they really knew how to put up a show which won exhibitors’ hearts by stars actually engaging with them and put them first, coming down to #RyanGosling himself give them their flowers...
Accelerated Biological Aging Raises Dementia Risk in Women
Epigenetic Clocks of Biological Aging and Risk of Incident Mild Cognitive Impairment and Dementia: The Women's Health Initiative Memory Study "In this cohort study of older women, accelerated biological aging measured by AgeAccelGrim2 was associated with higher risk of incident MCI/probable...
Progress: More Forward Steps Than Backward, Over Time
Something I taught 14 yo: Most progress is a mix of steps forward and steps back, just with with more of the former. But you can get a run of steps back. So to judge progress accurately you need to...
Dreaming of a Two‑Story Closet, Maybe Three?
I want a two story closet. Anyone think I need a three story closet instead? 😂

AI Promises Optional Death by 2030
AI Can Make Longevity Real | Death Optional by 2030! https://t.co/E9M6hX47Aw #ArtificialIntelligence #Longevity #Immortality #Aging #MedicineOfTheFuture https://t.co/mHpaEZZKKd

Spielberg Debuts New Disclosure Day Footage, Pushes Longer Theatrical Window
But one of the biggest moments of #CinemaCon on WED was #StevenSpielberg for the first time ever visiting the convention to promote #DisclosureDay, unveiling new footage described as jaw dropping, saying he personally talked to #Universal’s marketing team not to...
Monkey Selfie Case Guides AI Art Ownership Debates
A famous monkey selfie is becoming relevant again in the AI era. The case around who owns art created without a human author is shaping how we think about AI-generated content and what counts as original work. As AI floods the internet...

Amazon MGM Pledges 15+ Theatrical Releases, Hits #2 Box Office
In an electric #CinemaCon panel, #AmazonMGM made it clear: it’s not an experiment, they are fully committed to theatrical, officially renewing their commitment to exhibitors to deliver AT LEAST 15 theatrical Releases per year, & announcing that #ProjectHailMary just had...
50 Cent Heads Street Fighter Pop‑up, Trailer Drops Tomorrow
50 Cent has taken over the #StreetFighter pop-up event at #CinemaCon. They just showed the new trailer - drops tomorrow. It’s awesome. https://t.co/NKrI4y2V6t
CinemaCon Delivers Massive Film Lineup, Disney & Paramount Reveal
As someone that loves movies I’m so happy to say this years #cinemacon has been fantastic. So so so many movies I can’t wait to see and tons of original films. And it’s not over. Tomorrow is Paramount and Walt...
Oasis' Comeback Tour Crowned Pollstar's Tour of Year
Oasis’ Comeback Outing Wins ‘Major Tour of the Year’ Prize at Pollstar Awards, as Kendrick Lamar/SZA, Benson Boone and the Weeknd Also Score Top Honors https://t.co/HMec1rn1cT via @variety
DIY Solar, EV, Battery
Sustainability guru Prof @PeterNewmanCUSP @CurtinUni on ABC Life Matters speaks about do-it-yourself, solar-led, EV-charged, home-battery powered, money-saving opportunities We need more It needs to be faster https://t.co/zz2A7TnPm3 No one will be elected saying no net zero
Design Better Signals, Not Mindsets, for True Calm
If your phone, room, schedule, and relationships keep teaching your organism to stay on watch, calm will always feel artificial. Recovery is rarely a mindset breakthrough. It is usually better signal design.
Neon‑lit John Wick Highlander Sneak Peek at CinemaCon
It's still filming, so it was a little behind-the-scenes clip - all sorts of neon. Basically a John Wick Highlander. I ain't mad at it. #CinemaCon
Spaceballs Returns with Star Wars‑Style Parody and Nostalgic Gags
First footage from Spaceballs: The New One just played. Big Force Awakens vibes. Dark Helmet has a Kylo Ren-type mask. Helmet fights Yogurt with three sabers. There are a ton of nods to the original - pizza, combs, flamethrower, etc. Ends...

Aged Polystyrene Microplastics Speed Worm Aging via Ferroptosis
Photoaged Polystyrene Microplastics Accelerate Aging in Caenorhabditis elegans via Ferroptosis-Linked Insulin Signaling Pathway https://t.co/gGPlKDdgW1 https://t.co/NZ31ToOTp2
Join Me and David Lowery at Angelika Tonight
come see this with me and david lowery at the Angelika tonight (Thursday) at like 7:30 or whatever

First Crawl: A Beautiful Milestone Tonight
Such a beautiful moment when I got to see my baby crawl for the first time tonight
Beehive Mayhem Meets Metallica in Over‑the‑Top Trailer
THE BEEKEEPER 2 trailer: a flamethrower down a throat, weaponized bees, Metallica’s “For Whom the Bells Tolls,” and a 1969 Dodge Super Bee. We can’t do better than this.

Public Can Instantly Download Raw Mars Rover Images
We have robots on Mars — 140 million miles away — actively sending us photos right now. And @nasa gives YOU the same access to those images as the mission teams. Download raw Mars 2020 images the moment they arrive: 👉 mars.nasa.gov/mars2020/multimedia/raw-images/
Colorado Leads Aerospace Innovation at Space Symposium
Great to be at the Space Symposium in Colorado Springs today, connecting with innovators and exploring the future of space. Colorado is proud to be the leader in aerospace—home to world-class companies, research institutions, and thousands of skilled workers helping...
Masa: Overrated Investor, Underrated Operator, Relentless Comeback
Just finished the Masa Son biography, Gambling Man, by Lionel Barber. Worth the read for some of the details: the sections on Wework and the vision fund, in particular, are absolutely insane. Hard to know what to make of Masa...
MGM Debuts Michael B. Jordan’s Bond‑Style Thriller Footage
MGM is starting now. First up, OSCAR WINNER Michael B. Jordan is here with the first footage from his 2027 film The Thomas Crowe Affair. MBJ vs. Branagh with Adria Arjona in the middle. It looks like a Bond movie....
Menopause Hormone Therapy May Influence Triple‑negative Breast Cancer Risk
Amen. I wrote about this in detail in my Substack about Triple Negative Breast Cancer and Menopause Hormone Therapy: https://open.substack.com/pub/drjordanemont/p/cancer-cases-triple-negative-breast?utm_campaign=post-expanded-share&utm_medium=post%20viewer
Get Your New Release in Front of Global Media
Got a new single, EP, or album coming? I get your music in front of journalists, tastemakers, and media across the U.S. and worldwide — with full SEO built in, so people can actually find you. Eric@ThatEricAlper.com

Amazon MGM Teases He‑Man Film, Possible Bond Reveal
Time for Amazon MGM presentation at #CinemaCon. Expecting latest new look at He-Man film Masters of the Universe. And could a Bond announcement be on the cards? https://t.co/j7i0PLDZeD

HOKUM: Adam Scott Shines in McCarthy’s Best Film
HOKUM traffics in sharp, frightful fare. Absolutely stomach-churning. Houses a well-written antihero driving the horrific hijinks where you wanna see him be terrorized as well as seek redemption. A dastardly good performance from Adam Scott. Damian McCarthy’s best film yet.
Why Great Memoirs Click—And Two Buzzers Miss
I read a lot of memoirs. This is an excellent discussion on what makes memoirs work, and why two of the buzzier ones at the moment haven’t quite clicked.
Great Successes Start with Repeated Rejections
If you’re considering quitting here’s a reminder. Steve Jobs was fired from his own company, Tesla almost went bankrupt, Jay-Z rejected by every major record label, Oprah fired from her first TV, Colonel Sanders rejected over 1,000 times trying to...

Unexpected Hit: “Walking on Sunshine” Became Timeless Anthem
On this day in 1985, Katrina and the Waves released "Walking on Sunshine." It was not even a favourite in the studio, but it became their defining hit, earning millions and lighting up films, ads, and playlists for decades. https://t.co/R3pYnCqqS2