Weight Control Depends on Calories, Not Lifelong GLP‑1
The most annoying question that everyone keeps asking me is if I have to continue to take a glp-1 for life. Stopping a glp-1 doesn't make you gain weight. Eating a calorie surplus makes you gain weight. I know exactly how to gain and lose weight and I'm great at both :-) All I need to do is stick to ~1800 calories a day and I won't gain a pound. I can do that on a glp-1 or off one. I'd personally rather do it on one because my only side effects have been VERY positive (e.g. I have not been interested in alcohol) but it's always a choice I can make.
Real Experiences: Exclusive Pumping's Impact on Milk Supply
If you exclusively pumped, I’d love to hear what influenced that choice for you. I’m considering it this time around and trying to figure out what might work best for me. Did it impact your milk supply at all or...
Tau Seeds Trigger Widespread Neurofibrillary Tangles via Connectivity
Tau seeds induce neurofibrillary tangle formation across brain regions via individual-specific connectivity • Tau seeds induce neurofibrillary tangles (NFTs) locally and across distal brain regions https://t.co/wcD6GdHHYF https://t.co/3pHuh7cdTi
AI Building Feels Like Minecraft—Need Real‑world Breaks
As a new AI builder, I find it very hard to stop working. It's kind of like playing in Minecraft all day. World building is fun and a bit too addictive. Forcing myself to stop and play some basketball with the...
Soyuz Tower Demolished, Repurposed for Maia Rocket
There are reports about the demolition of the service tower at the Soyuz launch pad in Kourou, French Guiana. It looks like this supposed video was badly squeezed horizontally. In 2024, the mothballed facility was re-assigned for the European Maia...
Stay Soft, Keep Sweetness, Embrace the World’s Beauty
“Be soft. Do not let the world make you hard. Do not let the pain make you hate. Do not let the bitterness steal your sweetness. Take pride that even though the rest of the world may disagree, you still believe it...
New Visuals Reveal URM-2 and URM-1 Adapters for Angara‑5
Rollout visuals released after today's Angara-1.2 launch, showed the URM-2 booster (bottom left) and an adapter for the core version of the URM-1 (bottom right) all required for the assembly of the Angara-5 variant: https://t.co/yFPl9kzmTN https://t.co/bTcyhQqEUF
Prepared, Paced, and Powered Through Boston 2026
Boston 2026 didn’t disappoint. Showed up feeling ready. Training was there, I felt strong Nutrition was dialed in, my energy high Pacing was right, quick, steady and sustainable And I finished strong 💪 #bostonmarathon #marathon #furlthefinish
Columbia Engineers Create Self‑Repairing, Self‑Upgrading Robots
Self-Repairing, Self-Upgrading #Robots Developed at Columbia #Engineering by @tweetciiiim #AI #Robotics #MachineLearning #ArtificialIntelligence #ML https://t.co/3U07MjpYDv
Find Freedom in Simple Breath and Presence
30 seconds to breathe and words to repeat [with the sounds of an open field]: “I am free to seek out spaces where I don’t feel obligated to perform and I free to simply be.”
WGA Warns Warner‑Paramount Merger Would Be Disastrous
WGA statement on Warner shareholders approving Paramount deal: The proposed merger of Paramount and Warner Bros. Discovery would be a disaster for writers, the entertainment industry, consumers, and the country. While shareholders approved this deal today, this merger is far from...
Overstimulation Makes Kids Demand Even More Attention
Why is it that when you’re overstimulated and try to get space, the kids need you 100x than they did before 😩 halpppp meeee rhonda
From External Influence to Inner Impact: A Half‑Inch Shift
As I said on 60 Minutes, “I used to work on the outside of peoples’ heads, now I work on the inside, so there’s only half an inch difference.” https://t.co/hFeIKJmtHW #entrepreneurmotivation #successmindset #keynotespeaker
Authentic Culture Cycles From Cringe to Trend, Then Back
There are still authentic expressions of culture. They’re just seen as cringe and unfashionable until they percolate into the level of mass consumption, after which they again become uncool. “I can only buy alt clothes from SHEIN,” is the apotheosis...
Strong Performances and Concerts, Yet Movie Feels
Michael has some fantastic performances from the leads & amazing concert reenactments. The movie falls short and feels like fan service. @michaelmovie #MichaelMovie https://t.co/rrOh1HaGOF
Information Overload Isn’t Knowledge—Act to Adapt
Although we have access to more information than ever before, that doesn’t mean we’re more knowledgeable. Moreover, what good is information if you don’t act on it? Here are 10 ways to adapt to a changing world: https://t.co/MbaNKFV2UD @fsonnenberg https://t.co/gs5rhGD30c
Ego Destroys Dreams; Service Builds Them
Ego is lifting up yourself and service is when you lift up others. Ego kills dreams and service creates them.
Meta-Analysis Flawed by Mixing Disparate Anti‑amyloid Agents
A harsh critique of the recent @cochranecollab meta-analysis of the anti-amyloid drugs for Alzheimer's disease https://t.co/EU4JMOVWkV 'These results and their overarching conclusion that “successful removal of amyloid from the brain does not seem to be associated with clinically meaningful effects in...
Scientists Convert pMMR Tumors to Immunotherapy‑Sensitive dMMR
For anyone else fried with #AACR26 abstracts, we can now look at them from a different lens...
Theron's APEX: A Streaming Original Worthy of “Real Movie” Status
THR's review of Charlize Theron in APEX: "It’s the rare breed of streaming original that can safely be called a real movie." https://t.co/j7OuIIYxJG
Theron and Egerton Deliver Thrilling River‑Wild‑Style Action in APEX
Baltasar Kormákur’s APEX on Netflix is very much my jam. Charlize Theron & Taron Egerton give us their gonzo, white-knuckle version of DEAD CALM and THE RIVER WILD. My review: https://freshfiction.tv/apex-review-charlize-theron-and-taron-egerton-get-dead-calm-on-a-river-wild/
Explore Colorado's Asian Flavors During Mile High Food Week
Colorado is home to a truly delicious restaurant scene offering tasty meals from around the world. Mile High Asian Food Week is an exciting opportunity for Coloradans to get out in our communities and visit delicious Asian restaurants. https://www.milehighafw.com
Drinking Maasai Cow Blood Reveals Timeless Survival Tradition
I drank cow’s blood in Tanzania and I’d go back for another cup. Sharing it with the Maasai was an invitation into something much bigger than a meal. It’s a practice rooted in tradition, tied to survival, and carried through generations....
Deliberate Controversy Fuels True Impact, Not Watered-Down Appeasement
If you are a people pleaser, you will give more total pleasure if you deliberately upset some portion of people. If your work is watered down it will never reach the tastemakers. Those people who hate it today won't have...
Agrivoltaics Preserve and Boost Forage Quality, Study Shows
Agrivoltaics maintain or enhanche forage quality, study finds #energysky -- via pv magazine global: https://t.co/fcVejDzobB
Continuous Glucose Monitoring Outperforms Self‑Monitoring in Type 2 Diabetes
A randomized trial of continuous glucose monitoring (CGM) vs self-monitoring for Type 2 diabetes on basal insulin and drug therapies shows superiority of CGM for gluocse regulation https://t.co/XUymGiov1c @TheLancetEndo https://t.co/lcjFDnEG6x
Alleged FDA Pressure Removes Study Confirming Long‑term Vaccine Efficacy
Vinay Prasad forced FDA scientists to withdraw a paper from Vaccine, the journal I am co-EIC of, because it showed that COVID vaccines work for everyone 6 months+. This is Gold Standard Science at Marty Makary’s FDA. Setting the Gold...
Drake's Recent Lead Singles Miss the Mark
i don't care if drake releases a single before the album because his recent 'lead single' track record includes "slime you out," "way 2 sexy," and "toosie slide"
Progress Drives Fast, High‑Quality Results
In the age we’re living in, we can’t settle for just getting the job done. It needs to be ✅ Done well ✅ Done fast How do you get something done well and fast when it’s not your normal? Progress.
Scalable Hypothesis‑testing Datasets Will Drive Biology’s AI ROI
Which AI-enabling datasets will bring the biggest ROI in biology? One type will be "ways to confirm hypotheses at scale". @GordianBio is building atlases of how every expressed gene target affects organs suffering diseases of aging.
NIH Director Censors Routine Vaccine Study Over Personal Dislike
To be clear: @NIHDirector_Jay reportedly took issue with the study design, which is routine for evaluating vaccines post-market. Podcast Jay, who has no expertise in vaccine trials, decided unilaterally he didn’t like it & thus censored results of studies our...
Bioethicist Vs. Germline Editing Entrepreneur Sparks Uneven Debate
Starting right now. Debate between I. Glenn Cohen (Harvard/reprogenetic bioethics) vs. Cathy Tie, 'serial' human germline editing startup entrepreneur. This should not be an fair fight, but Glenn Cohen is a nice guy...so https://t.co/qfqivoLvhV
Metformin Fails to Boost Walking Distance in PAD Patients
Metformin to Improve Walking Performance in Lower Extremity Peripheral Artery Disease: The PERMET Randomized Clinical Trial "Among people with PAD without diabetes, metformin did not improve 6-minute walk distance at 6-month follow-up compared with placebo. These results do not support metformin...
C&S Launches National Drive to Empower Young Leaders
Formerly the Institute for Citizens and Scholars, and before that the Woodrow Wilson National Fellowship Foundation, C&S has launched an ambitious effort to inspire young leaders across the country. Connie Matthiessen Reports: https://tinyurl.com/5x9jkpnj Related IP Resources: Civic & Democracy Funders -https://tinyurl.com/4zbzy78h State of American...
Start Your New Year Transformation Today
The start of a new year is naturally a time to challenge everything you do, expand your thinking, refocus your efforts, and rededicate yourself to your future. If you haven’t done this already this year, why not do it today? #dailyquote...
Simple Habit May Prevent Alzheimer’s, 16‑year Study Finds
Want to Protect Your Brain From Alzheimer’s? A 16-Year Study Suggests a Simple Thing to Do Right Now https://t.co/JuRJJ4hRjE https://t.co/OeivZIC7Ln
5 Hours Weekly, 35 Years:
The investment: ~5 hours a week. Lifting heavy objects 3x a week, 2 work sets per exercise, 2-3 exercises (at least one compound movement) to failure and hiking or jog for an hour or so 1X a week, sprint intervals...
Solid‑state EV Batteries Promise 80% Charge in 7.5 Minutes
JUST IN: A Chinese company just recharged an EV from 0 to 80% in 7.5 minutes. Most people have no idea what this means. Greater Bay Technology just rolled its first all-solid-state EV battery cells off a production line. These cells hit 260-500...
NASA Moves Crew‑13 Launch to September, Resumes Six‑month Cadence
NASA announces Crew-13: NASA's Jessica Watkins and Luke Delaney, Canada's Josh Kutryk, Russia's Sergey Teteryatnikov. Launching in Sept instead of Nov as NASA resumes ~6-month cadence (instead of ~8). 2nd flt for Watkins, 1st for the others. https://t.co/rK0XBeLEjt
Psilocybin Reconfigures Cortical Inhibition via Interneuron Recruitment
wonky / important pre-clinial paper out of Alex Kwan's lab Psilocybin reshapes cortical inhibition through selective interneuron recruitment @kwanalexc https://t.co/OZX2cHDD94
Leaders Decide; Evidence Is Insight, Not Action
Stop asking insights to do the work of leaders. Evidence informs. Leaders decide. Organizations move or stall based on whether those roles are clear and enforced. Insight is evidence. Evidence demands interpretation. Interpretation demands decision. https://t.co/sQqOka4PcI https://t.co/qTcZsruswN
Agents Value Real Audience, Not Social Media Followers
Having a following is one aspect of getting an agent, esp. if you write nonfiction but it is by no means the most important thing. They are looking for an indication that you have an audience who might want to...
Switched to Apple Watch for Recovery and Bio‑Metrics
Ditched my whoop and I’m now fully back on the Apple Watch, there are apps that give you recovery, body battery, biological age
Resistance Training Counters Age‑related Muscle Loss and Restores Protein Sensitivity
Muscle loss with age is common, but much of that decline is driven by inactivity, not aging alone. On average, we reach peak muscle mass somewhere between 20 and 30, then lose about 8% per decade after that. By the time...
Study Confirms CBN Improves Sleep Quality
CBN (not CBD) strikes again with a study backing up what other research has shown: it’s *fantastic* for sleep quality (but I only use it when traveling, so I maintain sensitivity) - https://t.co/kP6dD1d129 https://t.co/1OYsI2gfZ5
432 Hz Music Relaxes Muscles, Enhances Yoga & Massage
432 Hz music are thought to have a soothing effect on the nervous system, helping relax muscle tension and decrease physical discomfort. This might be especially beneficial during yoga or massage therapy.
HBO to Produce Six‑Episode Series on Vrabel‑Russini Sc
Just waiting for the release to hit my inbox that HBO is developing a six episode limited series on the Vrabel-Russini scandal from the DTF ST. LOUIS creators
Modified Starch Boosts Fat Burn, Stabilizes Glucose, Risks Gut
Hydrothermally modified starch supplements may boost fat oxidation & stabilize blood glucose during exercise. But, slow absorption might upset your gut. Read more: https://t.co/Qb9hepjbPa https://t.co/NoOaX6lDJK
Validate Exclusion Pain, Reassure Child It’s Not Their Fault
Your child needs to hear, "Being left out hurts. It doesn't mean there's something wrong with you, though."
Michael Set to Shatter Global Opening Records, Outpacing Oppenheimer
#MICHAEL poised to crush industry’s 75M-85M 5-day opening projections overseas, kicking off its Global #BoxOffice run grossing spectacular 18.5M on WED Opening day at intl. markets, including TUE Previews, already beating #Oppenheimer’s 15.9M WED+THU grosses in just one day. Opening could...