60‑Year‑Old Looks 30 Thanks to Simple Lifestyle
The man who defies aging 60-year-old Singaporean man, Chuando Tan, recently had his 60th birthday and still looks like he's in his 20s or 30s. Here's a breakdown of his diet, exercise, and other routines⬇️ https://t.co/Eio9MxFwNO
Mitochondria-Derived Vesicles Key to Brain Aging Control
Mitochondrial quality in aging and neurodegeneration: The emerging role of mitochondria-derived vesicles 🔎 Mitochondrial quality control contributes to preserve neuronal health… a focus on MDVs, their dysregulation during aging and neurodegeneration, and implications for biomarkers and therapeutic strategies. 🧠 https://t.co/8Hj3Rk2Q4Z
Upcoming Meeting to Shape Gerotherapeutic Regulatory Frameworks
Affecting the Aging Trajectory: Regulatory Constructs for Gerotherapeutic Drug, Biologic & Device Development 👉 “On May 27, 2026, the Reagan-Udall Foundation for the FDA, in collaboration with @ARPA_H and the @xprize Foundation, will convene a hybrid public meeting on exploring...
Age Is No Barrier: 67‑Year‑Old Lifts 420 Lb
Think you're too old for strength training? Watch this 67 year old woman pull 420 pounds. Want to improve your health and longevity? What are you lifting these days?
Transparency and Systematic Methods Prevent Anti‑Aging Grifts
Then be transparent & systematic Which is to say, open about hypotheses, methods, data, biases, @ processes. Otherwise you look like what you actually are, which is a grift for an anti-aging methods you’re trying to leverage without any of...
Curing All Diseases May Ultimately Converge with Solving Aging
Is "curing all diseases" essentially = "solving aging"? feel like @fedichev would disagree from a technical perspective, but perhaps the spirit of the mission inevitably results in convergence.
Diet Shapes Gut Metabolites, Amino
Correlations For Gut Bacterial Metabolites, Amino Acids, And The Omega-3 Index With Diet (Metabolomic Tests #23 and #24) https://t.co/rXwkEfxOA0 https://t.co/mBZEGGdb8S
Boost NAD to Revitalize Energy and Cellular Repair
When this happens, cells lose their ability to recover and repair as efficiently as they once did. Which is why fatigue, brain fog, skin dullness can start to appear. By supporting NAD levels, you can help sustain cellular energy and activate...
Just 11 Minutes More Sleep Cuts Heart Risk 10%
11 More Minutes of Sleep, 5 More of Activity: 10% Lower Heart Risk As a medical school professor, patients ask whether tiny lifestyle changes really do anything. New data from 53,000 adults says yes. European Journal of Preventive Cardiology, March 2026 (Koemel...
SIRT5 Crucial for Heart Health in Longevity Era
Unveiling the importance of SIRT5 for cardiac health and disease in an era of increasing longevity https://t.co/a8fXNPRIKp
Gut Bacteria Species Are Actually Multiple Distinct Populations
Your Gut Bacteria Are Not What Your Textbooks Said As a medical school professor, I've taught gut bacteria as a list of species. A new Nature paper says many of those "species" are actually multiple distinct populations. Nature, May 2026 (University of...
Gut Metabolites Shape Immunity in Aging and Disease
Gut microbiota-derived metabolites as immune modulators in aging and age-related chronic inflammatory diseases https://t.co/iVUKH7ONVa https://t.co/8M3LmurbCa
SuperDNA: AI-Driven Biotech Hub Accelerates Drug Discovery
Welcome to SuperDNA Up City - this will be the true automation biotechnology + AI Disneyland with 10 thousand humans in the loop. Most people do not realize that even today, with 30 developmental candidates some of which often trigger...
Polypharmacy and Anticholinergic Load Accelerate Aging via Inflammation
Polypharmacy, anticholinergic burden and inflammation in relation to accelerated biological ageing Note the observational design, with corresponding limitation in inference. The authors concluded: "Both polypharmacy and anticholinergic burden are associated with accelerated biological ageing, partly mediated by inflammation, including a potential serial...
Microplastics Found in Chewing Gum: Longevity Warning
Follow the journey to live longer than anyone that has ever lived: Today's Diet (5/8/26); Microplastics in Gum https://t.co/NlaDOfWF4m
Bold Ambition Drives Growth, Inspires Longevity Ventures
Bold ambition pays off, and it tends to lift everyone around it. Elon, have you ever thought about starting a longevity company down the road? If not, what’s holding you back? If so, what would it take to make it happen?
Longevity Field Shifts From Consensus to Convergence
‘We are not at consensus but we are at convergence’ @LongevityTech @TinkingGumbel with @prof_horvath https://t.co/rGqQhNHYxw https://t.co/tcfNH3S2bH
Optimal Exercise‑Fasting Dose Boosts Metabolic Health
Optimal dosage of exercise combined with intermittent fasting for body composition and cardiometabolic health in adults: a systematic review and multilevel meta-analysis https://t.co/JFrFVMpGDq
We’ve Launched the Most AI‑discovered Longevity Drugs
This is cool. Not sure why you need so much money if you are making drugs faster and cheaper. But it is great - maybe I should be thinking about raising more to scale. At the end of the day,...
Smart Homes Integrated with Biotech Extend Lifespan
A bigger house is not going to give you significantly longer life. But a much smarter house integrated into the advanced biotechnology research and clinical ecosystem will. Very happy to see our chapter with CY Leung published in Springer Nature...
Mabwell IPO Highlights China’s Rising Biologics Powerhouse
Do you remember the company which sold their IL11 nanobody to Google Calico after it realized that after 13 years in the business they need a drug for aging? The company is called Mabwell and they just listed in Hong...
Rapamycin's 50-Year Odyssey: From Easter Island to Medicine
The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine https://t.co/Jn67QrGVi6 https://t.co/dwGPgUVB83
GLP‑1 and Testosterone Boosters Are Outright Scams
GLP-1 drops are a scam GLP-1 patches are a scam GLP-1 boosting supplements are a scam Also… Testosterone boosting supplements are a scam
Organ‑Specific Aging Clocks Reveal Multi‑Omics Lifespan Patterns
The big advance in the science of human aging is the ability to quantify it and relate the metrics to health and disease. A new paper today @CellCellPress takes this to the next level with organ clocks and multiple biologic...
Metformin's Primary Action Is Gut, Not Liver
Metformin, one of the most commonly prescribed drugs, was thought to work via the liver. Check that. It's primarily through the gut. @NatMetabolism https://t.co/i2CpZip61B https://t.co/bhsI7p7SYx
Heart, Kidney, Metabolic Issues Raise Cancer Risk 30%
Heart, Kidney, Metabolic Disease Linked to 30% Higher Cancer Risk As a medical school professor, I teach cardiovascular and cancer medicine as separate silos. A new study of 1.4 million adults says we have to stop. Circulation: Population Health and Outcomes, April...
IGF‑1 Switch Drives Biphasic SASP Aging Model
The IGF-1 senescence switch: a biphasic model for SASP-driven aging and precision senomodulation https://t.co/f0BoHbaeCK? https://t.co/NjDlT0O9hQ
Regular Fish Intake Supports Cognitive Health in Aging
Fish consumption and cognitive function in aging: a systematic review of observational studies "In conclusion, the evidence suggests that regular fish intake (typically ≥1–2 servings per week) is linked to preserved cognitive performance, although some inconsistent findings require further investigations." https://t.co/1axIS85WGf @GeroScienceAGE
Science Advances Toward Immortality Through Longevity Hacking
Longevity Hacking: Can We "Cure" Death? "For millennia, humanity has dreamed of immortality, but we are finally living in an era where science is catching up to the dream. "(Sparks) https://t.co/wv28wrTI77 #longevityhackers #longevity #science https://t.co/CTo5hLtD4a
Fuel Your Mitochondria, Unlock Peak Performance
I don’t take 150 pills a day to feel average. I take them because your biology responds to inputs, and most people never give their cells what they need to perform. Your mitochondria run the entire energy economy of your...
ART Reverses HIV‑Induced Aging, Cutting Years Off Biological Clock
Great news for HIV positive patients. A study presented at ESCMID Global 2026 found that untreated HIV can accelerate biological aging by up to a decade, but antiretroviral therapy can reverse this effect by nearly four years within about 18...
Only Proven Sleep Hacks Actually Improve Your Rest
I Tested Every Sleep Hack on the Planet — Here's What Actually Works https://t.co/13yp3N9anK via @YouTube
Psychedelic Figures Don’t Live Longer than Researchers
Psilocybin and human longevity "All groups exceeded population life expectancy, reflecting the effect of socioeconomic advantage on lifespan, but psychedelic personalities did not outlive cancer and aging researchers." 🙂"We examined mortality among prominent psychedelic personalities, researchers, and advocates who claimed psychedelic use...
AI Reads Retina to Diagnose Multiple Metabolic Diseases
In 2014 I predicted we'd diagnose metabolic disease just by looking into your eyes. Nature Medicine just published the proof. Researchers built an AI called Reti-Pioneer. You look into a camera. It scans your retina. No blood draw. No needles. No lab. What it can...
Clarify Healthspan: When Does Quality Living End?
Lifespan stops at death, but when does healthspan stop? "...Greater conceptual clarity is essential..." https://t.co/ybrK3kkQCS
AI Longevity Promises Overlook Tiny Real-World Gains
If you hear another AI celebrity telling you on stage that in the next 5 years we will double lifespan or eliminate all diseases - please show them this output from their own LLMs and ask them "How?". This simple...
Recent Longevity Pioneer Deaths Urge Faster Breakthroughs
Craig Venter (79), Ham Smith (94) and Clyde Hutchinson (86) died in the span of just 12 months. Time to accelerate, my friends. It would be sad if we land on Mars and don't make a significant breakthrough in longevity......
GLP Success, Injection Comfort, and Broad Curiosity Fuel Peptide Boom
3 things set the stage for peptides to become a WAY bigger than “supplements”: 1) GLPs (with RCT support) inadvertently made the “peptide” label seem generally approachable 2) GLPs made people less wary of injecting themselves 3) Women & men of many ages...
10 Simple Habits Linked to Healthy Aging
I’m a bioscientist studying aging 🧬 Here are 10 simple habits most strongly associated with healthy aging ↓
Mild Sleep Loss Alters Blood DNA Methylation Patterns
Prolonged Mild Sleep Restriction Changes Epigenome-Wide DNA Methylation in Peripheral Blood Cells: A Randomized Crossover Trial https://t.co/nb9s0AP9O1
SGLT2 Inhibitors Cut Cardiovascular Death by 14%
As a medical school professor: when I trained, "diabetes drugs" meant blood-sugar drugs. That ceiling has been broken. Meta-analysis in Am J Med (Jaiswal et al, U Chicago, Mar 26 2026) pooled 18 RCTs, n=95,913 patients with diabetes, heart failure, or...
10‑Marker Bioage Score Outperforms Chronological Age
As a medical school professor: chronological age is a tax bracket. Biological age is the actual bill. Aging Cell paper from MARK-AGE (Moreno-Villanueva, Burkle et al, U Konstanz, 2026) screened 362 biomarkers in ~3,300 adults across 8 European countries, then distilled...
Maintain Strong Paraspinal Muscles Into Your 60s
Train. This is what your paraspinal muscles should look like in your 60s and beyond. https://t.co/XR59But4a9
High Hs‑CRP, Not LDL, Drives Statin Benefit
"But my cholesterol is normal." JUPITER trial (NEJM): 18,000 people, normal LDL, high hs-CRP. Statin → cardiac events ↓44%, heart attacks ↓54%, strokes ↓48%. 322,000-person UK Biobank: hs-CRP outranked LDL. Full episode 🎙 https://youtu.be/FBLB1CQGBPM
Longevity Genes Can Switch From Benefit to Harm
As a medical school professor, I tell students: be careful with "longevity gene." Prof. Nikolai Slavov (Northeastern) just argued that single "longevity genes" are oversimplified. The same gene's effect on lifespan can flip sign with age -- helpful early, harmful later....
Invasive Nanowire BCIs Needed, Non‑Invasive for Biomarkers
I love brain-to-computer interfaces and one of my first papers and granted patents was in AI/ML for BCI. And I was very much impressed with BrainCo's non-invasive BCIs and artificial limbs and sensing fingers (that they sell to Tesla btw)....
Extracellular Vesicles Deliver SASP, Fuel Aging, Offer Therapies
Extracellular Vesicles as Key SASP Carriers Driving Cellular Senescence, Inflammaging, and Therapeutic Opportunities in Aging and Age-Related Diseases https://t.co/SURS5ZbTD9 https://t.co/IXM2BkdurZ
True Fitness Lies in Metabolic Flexibility, Not Looks
What is fitness, and what is the concept of being metabolically fit? We use the word 'fitness' constantly... but I hear so many different definitions of it. If you asked ten people at a gym what it means to be...
Science and Gadgets Extend Athletes' Careers Beyond Age
The Longevity Secrets Helping Athletes Blow Past the Limits of Age With cutting-edge sports medicine and sci-fi gadgetry, more and more athletes are figuring out how to extend their careers. https://t.co/RsXENoJYgj
New Liver Replacement: Prime Strategy for Aging Liver
The best treatment for aging liver is the new liver. Replacement is a viable long-term therapeutic and longevity strategy. Great insights from the replacement workshop organized by Sierra Lore and team as part of @ARDD_Meeting https://t.co/xYFQ9Fy2Jc https://t.co/ipQfpxcRNq