Most Tendon Pain Is Self‑Inflicted—Here’s Why
Tendon pain is the most common reason people come to see me. Most of it is self-inflicted — from doing too much, too soon, or from doing too little for too long. Let's review what most people (including many doctors) don't understand about why tendons hurt and how to fix them. 🧵
Combined Creatine, Carbs, and Protein Boost Sprint Performance
Synergistic effects of creatine, carbs and protein 📈 This new study recruited 60 male participants who were randomly assigned to either… 1️⃣ Creatine (0.3 g/kg) 2️⃣ Creatine + Carbs (1.0 g/kg) 3️⃣ Creatine + Carbs (0.8 g/kg) + Protein (0.2 g/kg) 4️⃣ Placebo Each supplement was...
Muscle Damage Drives Overreaching From Cumulative Fatigue
Overreaching is the result of accumulating post-workout fatigue. It is possible that muscle damage may accumulate to a greater extent than the other post-workout fatigue mechanisms. Read more in the weekly free Patreon article. https://t.co/BddbpAg3lx
Loss of Smell Predicts Five‑year Mortality Risk
A failing sense of smell may be an early warning sign of biological decline. In a study of ~3,000 older adults, those who couldn’t identify common odors had 3–5x higher risk of dying within 5 years, independent of disease, smoking, or...
Key Habits Shared by the World’s Longest-Lived People
What do the oldest people in the world have in common? Longevity expert explains ☝🏼 #longevity #doctor #health #wellness #diet
Regenerative Medicine Needs Data Over Hype
I recently had the opportunity to sit down with Scott Carney for a wide-ranging conversation on regenerative medicine, stem cells, peptides, and the growing gap between scientific promise and clinical reality. In the conversation, we dig into: – Why stem cell therapies...
Banister Model: Only Load and Timing Matter
Something I always find offers perspective... The Banister model is still a good model. It explains a large portion of athletic performance. It doesn't factor in all of the fancy stuff - whether you do 4 or 8 minute intervals, whether you...
GLP‑1s Reveal Calorie Restriction as Longevity Key
Its interesting that for the thousands of books written on health, we've learned since GLP-1s came on the market the best way to extend lifespan is to eat fewer calories
Ten Squats Every 45 Minutes Outperform 30‑Minute Walk
10 squats beats a 30 min walk. For blood sugar control after a meal, doing 10 squats every 45 minutes outperforms a dedicated 30 min walk by 14%. The mechanism: your quadriceps and glutes are the largest glucose sponge in your body....
SIRT6 Gene Therapy Remains Safe, Effective in Aged Beagles
Genflow sees sustained safety and efficacy in SIRT6 beagle trial 🐶 “Genflow Biosciences reported that three-month follow-up data from its SLAB trial in aged beagles show sustained safety and efficacy of its SIRT6 centenarian gene therapy, with no adverse events and...
Statins for Seniors: Benefits vs Diabetes, Alzheimer Risks
Should older adults use statins for heart health? Do statins increase the risk of diabetes and Alzheimer's Disease? Dr. Gregory Charlop shares the results of an important new health study. www.buckheadlongevity.com/blog/should-older-adults-use-statins-a-top-atlanta-longevity-doctor-answers
Single Gene Therapy Dose Eradicates Brain Tumors in Mice
GENE THERAPY SAFELY ERADICATES BRAIN TUMOURS IN MICE A single dose of an innovative gene therapy could eliminate hard-to-treat brain tumours and prevent them from coming back, according to a pre-clinical trial in mice, reported in Nature. “More than 80 per cent...
Urolithin A Enhances Mitochondrial Health and Endurance
I'm fascinated by Urolithin A. It's a compound that stimulates mitophagy (mitochondrial autophagy), helping clear out and replace damaged or dysfunctional mitochondria. Recent studies show that urolithin A improves endurance performance and even keeps immune cells "younger" with age. The data are early...
Disabling Light Sensing Extends Worm Lifespan by 40%
Great study in the bristleworm showing that light perception can regulate lifespan. Disrupting light sensing slows development, prolongs growth and extends lifespan by ~40%. More evidence that aging is not just damage accumulation, but is modulated by developmental processes.
Elite Runners Prioritize Sharpening Over Traditional Tapering
How should you Taper or Peak? Why the research doesn't align with what actual elite runners do...the difference between tapering and sharpening, and so much more. A new video deep dive on Youtube: @ SteveMagness Link below:
Modifying Gut Microbiome Boosts Memory, Slows Dementia
As a medical school professor, I teach that the gut-brain axis is real. But even I was surprised by this. A review in Nutrition Research confirmed: reshaping the gut microbiome can enhance cognitive performance and slow dementia progression. Key findings across multiple...
Science-Backed Sleep Aids: Ingredients & Supplements Explained
What ingredients and supplements help you to sleep better? Get the facts without the hype. Register to the webinar: https://t.co/6Nswtdw8XP https://t.co/gXE2Qm6x6D
Walk After Meals to Slash Post‑meal Blood Sugar
An underrated habit for longevity? Walking after meals. Blood sugar control is fundamental to healthy aging. Contracting your muscles helps shuttle glucose into them and can reduce the post-meal rise by 20-30%. Just 10-15 minutes is enough. Small habit. Big metabolic return.
NRH Prevents Age‑related Hearing Loss via Sirt3‑mediated Ferroptosis Suppression
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation https://t.co/MOqQblWYNM https://t.co/uhSMXRIxDK
Know Your Metabolic Profile, Not Just VO2max
The reason you should know your VO2max, ironically, has nothing to do with VO2max. It’s because you should know your metabolic profile: How much fat vs carbohydrate you burn at different intensities 🔥 And that requires a metabolic cart.
DIY Glucose Monitoring Revealed Hidden Liver Disease and Tech Limits
I spent over a year testing over-the-counter CGMS (also known as glucose biosensors) as a non-diabetic. The process helped me get an official MAFLD diagnosis. It also highlighted the shortcomings of wearable tech, data overload, and how mental health remains...
Jump Height Alone Misses True Power Development
When evaluating power development progress - even on force plates - it's easy to just look at vertical jump height. However, as @CresseySP sports science coordinator @YKahook shares in today's guest post, that approach can fall short: https://t.co/bHXkGMwJC7 https://t.co/tB1Y1ArJKi
Nine Hours of Sleep Boosts Mood, Metabolism, and Recovery
Benefits of 9 Hours of sleep: • Better hormone regulation (including those affecting appetite, stress, and metabolism) • Improved mood, focus, memory, and emotional resilience • Stronger immune function and faster recovery from exercise or daily stress • Support for...
Caffeine Boosts Endurance Performance: How It Works
There is a substantial amount of evidence that caffeine has ergogenic effects, especially for endurance performance but how exactly does caffeine work? Read the full blog: https://t.co/4MicON03gV https://t.co/U5RpJzg2n2
Hypothalamic Switch Determines Appetite, Influences Obesity Risk
As a medical school professor, this is one of the most eye-opening findings I've seen in metabolic research. UT Southwestern researchers discovered a molecular "switch" in the hypothalamus that decides whether brain cells become appetite-suppressing or appetite-stimulating. The transcription factor Otp directs......
Creatine Outperforms Protein and Omega‑3 for Strength
Protein vs creatine vs omega-3 for trained athletes 🧐 This new meta-analysis compiled data from 35 trials (1211 participants) to establish which supplements… 🥤 Protein 💊 Creatine 🐟 Omega-3 …are best for athletic performance outcomes including muscle strength, endurance performance, and recovery 🔍 Here is what...
Training at 62 to Prevent Gradual Decline
Why I Train This Way at 62 1/ I’ve been an orthopedic surgeon for nearly 30 years, and over that time, I’ve watched something happen to many of my patients that isn’t dramatic or sudden, but ends up being far more...
Exercise 60‑75 Min Daily Offsets Long Sitting Risk
Sitting a lot isn’t equally harmful for everyone. In this meta-analysis of >1 million adults, people who sat >8 h/day had no increased mortality risk if they also did about 60–75 min/day of moderate physical activity. (35.5 MET h/week). People doing...
Larger Muscle Fibers Waste Away Faster than Smaller Ones
In animal models, the largest fibers in a muscle atrophy faster and to a greater extent than the smallest fibers. Also, the rate of atrophy is fastest initially (when fibers are larger) and slower later (when fibers are smaller). Fiber...
Lithium Reverses ApoE4 Cellular Deficits, Merits AD Trials
https://t.co/r6JzHA1RxM with ApoE4/E4 from a sporadic Alzheimer's disease patient "Given the drug's demonstrated efficacy in reversing ApoE4-driven cellular vulnerabilities, lithium salt warrants further investigation for the treatment of AD." https://t.co/r6JzHA1RxM https://t.co/v2lE0XhN7n
Molecular Evolution Explains Animal Aging Diversity
Molecular evolution of animal aging 🗣️"...As a step toward this goal, this field perspective outlines general biological mechanisms that help explain the variability in aging patterns and longevity across the animal kingdom..." https://t.co/mHVAlyQbfM https://t.co/NoronuZDaL
Not Smoking Wins; Proactive Healthcare Dominates Longevity Bracket
The Longevity March Madness Final Four is Set: Here’s a wrap-up of how the four division finals played out. Lifestyle: A heavyweight classic It doesn’t get bigger than this. Top-seeded Not Smoking held off a furious push from Strength Training, surviving 53–47 in...
Targeting Liver ApoE Boosts Bone Healing in the Elderly
Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing "Our work here identifies novel liver-to-bone cross-talk and a noninvasive, translatable therapeutic intervention for aged bone regeneration" https://t.co/KSzvkKOzZt https://t.co/1p0cXQlalT
Conjugated PUFAs Target Senescent Cells
Polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells “ Conjugated PUFAs α-ESA and its methyl ester selectively eliminate diverse senescent cells… These lipid senolytics reduce tissue senescence and extend health span in aged mice” 👉 Lipid peroxidation underlies selective vulnerability...
Follistatin: Dual Weapon Against Cancer and Muscle Loss
Follistatin protein, which plays a key role both in inhibiting tumors and promoting muscle tissue growth. https://t.co/OebCo6FSI7
Fatty Acids Target and Eliminate Aging “Zombie” Cells
NEW STUDY finds certain fatty acids selectively kill senescent "zombie" cells. The molecules exploit a fundamental biophysical weakness in senescent cells, a totally new approach. Could we simply consume these moleculs to treat aging? ...🧵 https://t.co/EceCAfdlvz
Weight‑loss Drugs Boost Life by Aiding Sick, Not Slowing Aging
Weight loss drugs may increase human longevity but that's because they reduce the mortality of folks at the lower end of the lifespan distribution (i.e., unhealthy individuals), not because they delay the aging process. That's still valuable, but if this is...
Funding Hurdles Stall Needed Multi‑site BPC‑157 Trial
I can’t see any reason why a proper multi site RCT of BPC157 done by a few independent groups wouldn’t help clarify any real vs placebo effects. The challenge: no one wants to pony up the $ (more like $$$$...
First Human Trial Tests Cellular Age Reversal Therapy
This method to reverse cellular ageing is about to be tested in humans A burgeoning field is launching its first clinical trial to find out whether dialling back cell development can safely refresh aged tissues and organs. 💡"Technologies to refresh ageing tissue...
US Obesity Rates Dip in 2023, Drug Impact Suspected
BMI and obesity prevalence in the US decreased in 2023 for the first time in more than a decade. What s the reason? Are people 'exercising more and eating less' or are GLP-1 agonists starting to have an effect? https://jamanetwork.com/journals/jama-health-forum/fullarticle/2827712 @GatlanHealth
Coconut Water Matches Sports Drinks for Rehydration
This just in: coconut water (despite having lower sodium) is just as good as common branded “sports electrolyte drinks” for rehydration: https://t.co/amq8BEvGp0 https://t.co/rPXZZeyq9Y
Top Experts Discuss Cutting‑Edge Longevity Strategies Live
Fund Longevity Live Stream Wednesday, April 8 11:00 AM - 12:00 PM EDT 🔗 https://t.co/gNCkMYxhfI @aubreydegrey — Combination therapy @LidskyPeter — New theory of aging Alexander Panchin — Gene therapy & science communication @longevion — Crypto & funding @cordeiro — Global longevity movement @ILAISRLA ...
Latex Fails; Nitrile Blocks BPA From Thermal Receipts
Why won't latex gloves protect you from BPA/BPS in thermal receipts (or EKG paper)? Latex (natural rubber) is permeable to BPA/BPS. These chemicals dissolve into the latex polymer and slowly migrate through to your skin, especially with repeated handling throughout the...
Brain Aging Isn't Inevitable: Basics Beat Supplements
We talk a lot about brain aging as if it’s inevitable. It’s not. In my latest podcast conversation with @DrRagnar—author of The Stimulated Mind—we unpack what’s actually working for brain longevity and what isn’t. A few takeaways that stood out to me: • The...
Aging Intervention Possible—Now Prioritize Safety and Frequency
The question is no longer if we can intervene in aging. It’s how safely and how many times
Fund NIH Trials to Validate Unapproved Peptide Safety
I thought this was an excellent, balanced article on the current state of unapproved peptides from a safety and regulatory perspective by @AnjeanetteDamon in @propublica https://t.co/DbA8cdvTY5 The fundamental problem is that we don't have quality data on safety or efficacy for...
Oxytocin Reverses Isolation‑induced Neuropsychiatric Deficits via Brain, Immune, Microbiome
Oxytocin attenuates isolation-evoked emotional and social behavioral dysregulation through neural, immune, and microbiota mechanisms "Our study confirms the therapeutic effects of OXT in reversing isolation-induced neuropsychiatric disorders and elucidates its potential regulatory mechanisms, offering important implications for clinical interventions." https://t.co/hXkWRD1gMV
Higher Protein Intake Reverses Sarcopenia in Elderly Women
As a medical school professor, the protein recommendation I was taught -- 0.8 g/kg body weight -- is actively harming older adults. New data proves it. A 2025 Frontiers in Nutrition trial randomized 126 elderly women with sarcopenia into two groups...
Ultra‑processed Foods Hijack Brain Reward Like Cocaine
As a medical school professor, I have to be blunt: ultra-processed food is not just unhealthy. It is neurologically addictive. A February 2026 review in Pharmacological Research analyzed neuroimaging and molecular data and concluded: -- Ultra-processed foods activate the same dopamine reward...
The Vagus Nerve: Your Body’s Hidden Lifespan Connector
What if one small nerve quietly connects your brain to your heart, your gut, your immune system — and even how long you live? That was the question I brought to Dr. Elisabetta Burchi, a clinical psychiatrist, neuroscience researcher, and Head...