News•Feb 26, 2026
Synaptic Correlates of Benzodiazepine Tolerance
Recent pre‑clinical work has mapped the synaptic changes that underlie benzodiazepine tolerance. Chronic exposure uncouples GABA(A) receptors from their benzodiazepine binding site, down‑regulates α1‑subunit mRNA, and reshapes receptor trafficking through auxiliary proteins such as Shisa7. These alterations weaken inhibitory signalling, requiring higher drug doses to achieve the same anxiolytic or hypnotic effect. The findings clarify why long‑term benzodiazepine therapy often loses efficacy and precipitates dependence.
By Nature (Biotechnology)
News•Feb 26, 2026
Oportun Financial Corp (OPRT) Q4 2025 Earnings Call Transcript
Oportun Financial Corp reported a fifth straight quarter of GAAP profitability, posting $25 million net income for 2025 and an 89% jump in adjusted EPS to $1.36. Credit quality improved, with the annualized net charge‑off rate at 12.3% and secured personal...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
OrthoPediatrics Corp (KIDS) Q4 2025 Earnings Call Transcript
PolyPid announced successful completion of the Phase III SHIELD II trial, with D‑PLEX100 achieving its primary and key secondary endpoints and demonstrating a meaningful reduction in surgical site infections. The FDA provided written support for a rolling NDA review, and the company...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Kymera Therapeutics Inc (KYMR) Q4 2025 Earnings Call Transcript
Kymera Therapeutics reported Q4 2025 revenue of $2.8 million, entirely from its Gilead collaboration, while maintaining a cash balance of $978.7 million that extends runway into the second half of 2028. Adjusted R&D and G&A expenses fell 7% and 3% quarter‑over‑quarter, respectively....
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Morgan Stanley Direct Lending Fund (MSDL) Q4 2025 Earnings Call Transcript
Morgan Stanley delivered record 2025 results, posting $70.6 billion in total revenue and a historic $10.21 earnings per share. Total client assets rose to $9.3 trillion, while wealth management generated $31.8 billion in revenue and attracted $356 billion of net new assets. The firm’s...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
OPKO Health Inc (OPK) Q4 2025 Earnings Call Transcript
OPKO Health reported a $369 million cash position for Q4 2025, driven by asset sales, BARDA funding and partnership payments. The company repurchased 34.6 million shares for $47 million and allocated $109 million to stock and convertible note buybacks. Diagnostics revenue dropped to $71.1 million, but...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Nexstar, Scripps, Sinclair Express Regulatory Optimism
Broadcasters are buoyed by FCC Chair Brendan Carr’s hints of relaxed ownership rules and a Trump endorsement of Nexstar’s $6 billion Tegna acquisition. Nexstar, Scripps and Sinclair all highlighted this regulatory optimism in recent earnings calls, stressing strategic M&A and operational...
By Cablefax
News•Feb 26, 2026
Hilton Grand Vacations Inc (HGV) Q4 2025 Earnings Call Transcript
Hilton Grand Vacations reported fourth‑quarter 2020 revenue of $233 million, a 5% sequential increase, and adjusted EBITDA of $35 million (excluding a $3 million CARES Act credit). The company posted a net loss of $143 million, driven by a $209 million non‑cash land impairment. Contract...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Warby Parker Inc (WRBY) Q4 2025 Earnings Call Transcript
Warby Parker reported FY2024 revenue growth exceeding 15% and a 40% jump in adjusted EBITDA, driven by its strongest Q4 growth since 2021. The company opened 41 new stores in 2024, expanded its insurance network to over 30 million in‑network lives,...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Marcus Corp (MCS) Q4 2025 Earnings Call Transcript
Marcus Corp reported a 9.7% drop in consolidated revenue to $210 million for fiscal Q3 2025, driven primarily by a 16% decline in theater revenue and an 18.7% fall in attendance that left box‑office performance 3.8 percentage points below the national average....
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Compass Inc (COMP) Q4 2025 Earnings Call Transcript
Compass reported a 25.9% year‑over‑year revenue increase in Q4 2024 and generated $16.7 million of adjusted EBITDA, rising to $20.9 million when excluding Christie's acquisition costs. The broker added 669 principal agents in the quarter, boosting its net principal agent count by...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Comcast Gets ESPN Unlimited
Comcast is now granting eligible Xfinity TV customers free access to ESPN Unlimited, the sports network’s direct‑to‑consumer app, once they authenticate their subscription. The offering unlocks the full suite of live sports, original shows, and on‑demand content without an additional...
By Cablefax
News•Feb 26, 2026
Vericel Corp (VCEL) Q4 2025 Earnings Call Transcript
Vericel Corp. reported record third‑quarter revenue of $67.5 million, driven by a 25% jump in MACI sales to $55.7 million and a 21% rise in burn‑care revenue. Margin expansion outpaced top‑line growth, with adjusted EBITDA climbing 70% to $17 million and gross profit...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Purecycle Technologies Inc (PCT) Q4 2025 Earnings Call Transcript
PureCycle Technologies reported Q4 2025 revenue of $2.7 million, marking a fourth consecutive quarter of sequential growth, while achieving record production at its Denver (14 million lb processed) and Ironton (7.5 million lb produced) facilities. The company reduced feedstock procurement costs by $0.06 per pound,...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Sempra (SRE) Q4 2025 Earnings Call Transcript
Sempra reported adjusted Q3 2025 EPS of $1.11, a 25% year‑over‑year rise, while GAAP earnings fell to $0.12 per share because of a $514 million non‑recurring tax charge. The company reaffirmed its 2025‑2026 adjusted EPS guidance and highlighted a $10 billion sale...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Frontdoor Inc (FTDR) Q4 2025 Earnings Call Transcript
Frontdoor reported Q3 2025 revenue of $618 million, a 14% year‑over‑year increase driven by volume growth and higher pricing. Adjusted EBITDA rose 18% to $195 million, with gross margin expanding to 57% and free cash flow conversion improving to 60%....
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Hudson Pacific Properties Inc (HPP) Q4 2025 Earnings Call Transcript
Hudson Pacific Properties reported a transformative 2025, completing roughly $330 million of strategic asset sales and over $2 billion of capital transactions that doubled its liquidity to $934 million. The REIT reduced net debt by 22%, improved its debt‑to‑book ratio to 31.9%, and...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Public Service Enterprise Group Inc (PEG) Q4 2025 Earnings Call Transcript
Pacific Gas & Electric reported full‑year 2025 core earnings of $1.50 per share, a 10% increase over 2024 and the midpoint of its guidance range. The company raised its 2026 core EPS outlook to $1.64‑$1.66, signaling another 10% growth year...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Millicom International Cellular SA (TIGO) Q4 2025 Earnings Call Transcript
Millicom (Tigo) reported a strong Q4 2020 rebound, adding a record 2.3 million mobile users and 103 k cable customers, lifting its total subscriber base to 42 million mobile and 4.5 million broadband users. Service revenue and EBITDA were essentially flat YoY, while operating...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Alpha Teknova Inc (TKNO) Q4 2025 Earnings Call Transcript
Alpha Teknova reported Q4 2025 revenue of $10.5 million, a 9% year‑over‑year increase and the fifth consecutive quarter of growth, driven primarily by its Lab Essentials catalog line. Lab Essentials revenue rose 16% to $8.3 million, while Clinical Solutions revenue slipped 13%...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Goldman Sachs BDC Inc (GSBD) Q4 2025 Earnings Call Transcript
Goldman Sachs reported a 27% rise in annual earnings per share to $51.32, driven by record $41.5 billion global banking revenue and strong performance across investment banking, FICC, equities, and asset‑wealth management. Return metrics improved, with quarterly ROE at 16% and...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
This Compound Enhances Long-Term Memory of Mice — but only in Females
Researchers injected acetate, a common metabolic by‑product, into mice and tested long‑term memory using spatial and object‑recognition tasks. Female mice that received acetate showed significantly better performance 24 hours later, while male mice displayed little to no improvement. The memory...
By Nature – Health Policy
News•Feb 26, 2026
KBR Inc (KBR) Q4 2025 Earnings Call Transcript
KBR reported a solid fourth‑quarter 2020, highlighting a 20% increase in government and technology backlog and a 15% rise in adjusted EBITDA. The company emphasized its transition to Sustainable Technology Solutions, targeting over $1 billion in revenue and mid‑teens margins for...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Rhythm Pharmaceuticals Inc (RYTM) Q4 2025 Earnings Call Transcript
Rhythm Pharmaceuticals reported a strong Q4 2025, with product revenue rising to $57.3 million—a 12% sequential increase and 37% year‑over‑year growth. Full‑year revenue jumped 50% to $194.8 million, driven by expanding U.S. sales and broader international access for IMCIVREE. The company highlighted...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Emergent BioSolutions Inc (EBS) Q4 2025 Earnings Call Transcript
Emergent BioSolutions reported a successful completion of its stabilization phase, cutting net debt by $156 million and improving leverage to 3.3x adjusted EBITDA. Adjusted EBITDA surged to $183 million, a $205 million swing from the prior year, while operating cash...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Delcath Systems Inc (DCTH) Q4 2025 Earnings Call Transcript
Delcath Systems reported record 2025 revenue of $85.2 million, driven by over 40% volume growth and 28 REMS‑certified treatment centers. Gross margins held at 85% for Q4 and 86% for the full year, while adjusted EBITDA turned positive to $25.1 million and...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
GigaCloud Technology Inc (GCT) Q4 2025 Earnings Call Transcript
GigaCloud Technology reported record Q3 2025 revenue of $333 million, a 10% year‑over‑year increase, and a quarterly EPS of $0.99. Growth was powered by a 70% surge in European revenue, bringing the region to $100 million, while product revenue rose 16% YoY...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Willdan Group, Inc (WLDN) Q4 2025 Earnings Call Transcript
Willdan Group reported its strongest quarter ever in Q4 2019, with contract revenue jumping 49.7% to $129.4 million and net revenue rising 51.8% to $61 million. The Energy segment led the surge, posting an 84.5% increase in net revenue, while adjusted EBITDA more...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Main Street Capital Corp (MAIN) Q4 2025 Earnings Call Transcript
Main Street Capital reported a GAAP net loss of $14.4 million for Q4 2025, but generated adjusted distributable earnings of $0.15 per share, bringing full‑year adjusted earnings to $0.64 per share. The loan portfolio expanded 13% to $2.7 billion, driven by 32...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Syndax Pharmaceuticals Inc (SNDX) Q4 2025 Earnings Call Transcript
Ascendis (SNDX) reported €720 million total 2025 revenue, driven by €477 million from Yorvipath and €206 million from Skytrofa. Q4 operating profit hit €10 million and cash flow reached €73 million, leaving €616 million in cash at year‑end. Management guided 2026 operating cash flow of roughly...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Nuscale Power Corp (SMR) Q4 2025 Earnings Call Transcript
Fluor Corporation reported $12 billion in new awards for 2025, with 87 % structured as reimbursable contracts, while deploying $754 million in share repurchases and receiving $2 billion from its NuScale Power investment. The Energy Solutions segment posted a $414 million loss, driven primarily by...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
MBIA Inc (MBI) Q4 2025 Earnings Call Transcript
MBIA Inc. reported a markedly narrower Q4 2018 GAAP loss of $7 million, driven by reduced loss‑adjustment expenses on its Puerto Rico exposure and lower LAE across structured‑finance assets. The company completed a restructuring of COFINA bonds, cutting insured debt service exposure...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
National Health Investors Inc (NHI) Q4 2025 Earnings Call Transcript
National MI (NMI Holdings) reported a record 2025 year, posting $388.9 million net income (up 8%), diluted EPS of $4.92 (up 11%) and a 16.2% return on equity. Insurance in force reached $221.4 billion, a 5.4% year‑over‑year increase, while fourth‑quarter new insurance...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Nexstar Media Group Inc (NXST) Q4 2025 Earnings Call Transcript
News Corp reported Q4 2025 revenue of $2.4 billion, a 6% year‑over‑year increase, and total segment EBITDA of $521 million, up 9% despite a $16 million one‑time charge at HarperCollins. Adjusted earnings per share rose to $0.40 and profitability margin improved to 22.1%,...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Kimbell Royalty Partners LP (KRP) Q4 2025 Earnings Call Transcript
Kimbell Royalty Partners reported Q4 2025 production of 25,627 BOE per day and adjusted EBITDA of $64.8 million, while proved reserves rose 8% to a record 73 million BOE. The company declared a $0.37 per unit distribution, a 6% increase, classified entirely as return of...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Playtika Holding Corp (PLTK) Q4 2025 Earnings Call Transcript
Playtika reported $604.6 million revenue for Q3 2025, with GAAP net income of $39.1 million and adjusted EBITDA up 30% sequentially. Direct‑to‑consumer (D2C) revenue reached a record $209.3 million, representing 31% of total revenue and moving toward a 40% target within two years. Disney Solitaire,...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
BioCryst Pharmaceuticals Inc (BCRX) Q4 2025 Earnings Call Transcript
BioCryst Pharmaceuticals reported a 37% year‑over‑year rise in Orladeyo revenue to $159.1 million in Q3 and lifted its 2025 sales guidance to $590‑$600 million. The company completed the divestiture of its European business, repaid a $200 million term loan and entered Q3 with...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Eagle Point Income Company Inc (EIC) Q4 2025 Earnings Call Transcript
Eagle Point Income Company reported Q3 2025 results, with NAV increasing to $14.21 per share and recurring cash flows covering distributions. Net investment income after losses was $0.26 per share, while the board reduced the monthly distribution to $0.11 amid...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Teleflex Inc (TFX) Q4 2025 Earnings Call Transcript
Teleflex reported 2025 adjusted EPS of $6.98, an 8.7% increase, while outlining a $2.03 billion divestiture plan that will net roughly $1.8 billion after tax. Management pledged to allocate $1 billion to share repurchases and use the remaining $800 million to reduce debt, bolstering...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
Intellia Therapeutics Inc (NTLA) Q4 2025 Earnings Call Transcript
Intellia Therapeutics announced that the FDA has placed a clinical hold on its nex‑z MAGNITUDE and MAGNITUDE‑2 Phase III trials after a patient death and liver enzyme abnormalities. The company is implementing intensified safety monitoring and data reviews while awaiting regulatory...
By Motley Fool – Earnings Transcripts
News•Feb 26, 2026
International Seaways Inc (INSW) Q4 2025 Earnings Call Transcript
International Seaways reported Q3 2025 net income of $71 million ($1.42 per share) and adjusted EBITDA of $108 million, while generating roughly $63 million of free cash flow. The company ended the quarter with $985 million of total liquidity, a cash balance of $413 million...
By Motley Fool – Earnings Transcripts
News•Feb 25, 2026
Northern Territory Hails Record Gold Production Amid Exploration Push
The Northern Territory recorded a $1.7 billion gold output in 2024/25, aiming for a $2 billion target. Mining Minister Gerard Maley stressed that the region remains under‑explored and called for intensified prospecting to sustain future projects. The government also seeks to broaden...
By Australian Mining
News•Feb 25, 2026
Ex-BBC News CEO Denies Anti-Trump Bias Amid $10 Billion Suit
Former BBC News CEO Deborah Turness acknowledged that a Trump‑focused Panorama documentary failed editorial standards, yet she rejected claims of institutional anti‑Trump bias. The documentary’s edit prompted President Donald Trump to file a $10 billion defamation suit against the BBC, which...
By The Wrap
News•Feb 25, 2026
UN Calls for Ocean Governance to Abide by International Law
UN experts urged that upcoming seabed governance regulations, including deep‑sea mining rules, be anchored in international human‑rights and environmental law ahead of the International Seabed Authority's 31st session. They stressed state obligations to protect the climate system, prevent human‑rights harms,...
By JURIST
News•Feb 25, 2026
Anthropic Acquires Computer-Use AI Startup Vercept After Meta Poached One of Its Founders
Anthropic announced the acquisition of Vercept, a Seattle‑based AI startup known for its computer‑use agent Vy, and will retire the product by March 25. Vercept, which raised $50 million from investors including Eric Schmidt and Jeff Dean, joins Anthropic’s Claude Code team following a...
By TechCrunch — Mergers & Acquisitions
News•Feb 25, 2026
Warfighting Acquisition Transformation to Bolster DAF Battle Network Delivery
At the February 25, 2026 Air & Space Force Association Warfare Symposium, senior DAF leaders reaffirmed the critical role of acquisition transformation within the Battle Network framework. They emphasized maturing the network architecture to deliver warfighting capabilities at operational speed....
By U.S. Space Force – News (All Entries)
News•Feb 25, 2026
3ME Technology Eyes Arctic-Ready Battery Systems Under South 8 LOI
3ME Technology and South 8 Technologies have signed a Letter of Intent to develop lithium‑ion batteries for extreme cold‑weather and Arctic defence use. South 8 will supply its LiGas‑enabled cells, which operate from –60 °C to +60 °C, for integration into 3ME’s EdgeVOLT Cold...
By Australian Manufacturing
News•Feb 25, 2026
Hawthorn FC Names Anker SOLIX as Official Home Battery Partner
Hawthorn Football Club announced a premier partnership with Anker SOLIX, naming the global home‑battery leader its Proud Official Home Battery Partner. The deal coincides with Australia’s Cheaper Home Batteries Program, which offers rebates to spur residential energy‑storage adoption. Hawthorn members will...
By RenewEconomy
News•Feb 25, 2026
Colorado Lawmakers Look to Require Public Defenders, Livestream Hearings at Municipal Courts
Colorado lawmakers advanced HB26-1134, the Fairness & Transparency in Municipal Court bill, to require public defenders, ensure attorney access to case files, and mandate livestreamed municipal court hearings. The legislation responds to cases like a 30‑day jail sentence for a...
By Courthouse News Service
News•Feb 25, 2026
PMK Names Leah Sparkes VP, Ulisses Rivera Joins as Senior Account Director
PMK Entertainment announced two senior hires: Leah Sparkes as Vice President of Television, Film and Premium Content, and Ulisses Rivera as Senior Account Director in its Strategic Communications Group. Sparkes arrives with more than two decades of high‑profile publicity experience...
By The Wrap