Orion Leaves Lunar Sphere, Crew Chats with ISS
Orion will depart the sphere of lunar influence today at 1:25 pm ET and the crew will speak to the ISS astronauts at 2:40 pm ET. Mission status briefing at 4:30 pm ET. List of events (times subject to change): https://t.co/CR88eAwACM
Courage Guides Action; Agency Lacks Moral Direction
"'Courage' has a moral valence that agency doesn’t. Agency is about action, but it tells us nothing of direction. You can just do things, sure, but what will you do?" We've "collectively lost a sense of moral guidance" and don’t...

Gratitude Multiplies and Lights up Your Life
A dose of gratitude goes a long way. When we focus on the things for which we feel grateful, they seem to multiply. With a grateful heart, we can share our true selves with the world and let our light...
Schedule Tasks by Stimulation, Not Importance, Boosts ADHD Productivity
Productivity trick for ADHDs: Schedule tasks by stimulation, not importance. Most productivity advice tells you to organize your day by priority. Most ADHD brains don’t care about what’s “most important”. Their brains choose tasks based on stimulation, friction, dread, novelty, and whether the...
Only 1% Truly Thrive in Entrepreneurship
The cold hard truth: Most people are borderline incompetent. They make horrible decisions, constantly self-sabotage themselves, and have zero ability to delay gratification. This group basically gets supported by the other 50%. These folks take more value than they add. The next 45% is...
Aging Intervention Possible—Now Prioritize Safety and Frequency
The question is no longer if we can intervene in aging. It’s how safely and how many times

Celebrating Al Green's 80th with a Catalog Club
Al Green turns 80 on April 13. To mark this milestone I'm doing my Catalog Club series this month on four of his albums, starting with my personal favorite. Come luxuriate in some of the greatest music ever with me! https://t.co/ytNQm470sl...
China Claims 99% Cost Cut for Military‑grade Infrared Chips
China reports 99% cost cut on military-grade infrared chips Researchers have developed a new way to make high-end infrared chips that could slash their cost and boost smartphone cameras, self-driving cars https://t.co/t52LLpN3xK via @scmpnews
Mysterious VHS Tapes Hint at Boards of Canada Return
Mysterious VHS tapes seemingly point to the return of Scottish duo Boards of Canada https://t.co/ee2jnzoXWt
Purpose Deficit May Accelerate Biological Aging
This is one of the most interesting theories I've seen in a long time. Could aging be partly a cybernetic problem? In other words, we run out of goals, meaning, purpose, and that accelerates the biological aging process. There is...
Fund NIH Trials to Validate Unapproved Peptide Safety
I thought this was an excellent, balanced article on the current state of unapproved peptides from a safety and regulatory perspective by @AnjeanetteDamon in @propublica https://t.co/DbA8cdvTY5 The fundamental problem is that we don't have quality data on safety or efficacy for...
Luck Is a Habit, Not Random Chance
The people who seem "lucky" almost always have a habit you don't see. They read more, they reach out more, they show up more. Luck is intentional, but it looks random from the outside.
Safer Together Plan Prioritizes Nurses' Physical and Mental Health
The Safer Together National Action Plan includes protecting #nurses + healthcare workers physically + mentally, it may hold it all together. 🎧 Episode 132: Safer Together | The #Nurse Well‑Being Imperative Apple: https://t.co/6yY7RbqjRc Spotify: https://t.co/j3wvzMNTbL @ANANursingWorld @TheIHI
Astronauts Reveal Awe: Embrace Feeling Small
The Overview Effect: What We Can Learn From Astronauts About the Importance of Feeling Small, by @sambmd Good advice on getting more awe into your life: https://t.co/mAAM4VEEe4
Early Wake, Silent Minutes Boost My Weekly Health
I woke up at 4:29 am. Laid in the dark for eleven minutes doing nothing. It might be the healthiest thing I've done all week. Then I measured it.
Trauma Healing Is Messy, Non‑Linear, Not a Destination
What We Think Trauma Healing Is Vs What It Really Looks Like: Misconception: • A Linear Journey. • Eliminating Pain. • Swift And Silent. • Control Over Emotions. • A Destination. Reality: • A Non-Linear Spiral. • Building Capacity. • Somatic Release. • Increased Awareness. • Messy Growth. • Small Choices.
Oxytocin Reverses Isolation‑induced Neuropsychiatric Deficits via Brain, Immune, Microbiome
Oxytocin attenuates isolation-evoked emotional and social behavioral dysregulation through neural, immune, and microbiota mechanisms "Our study confirms the therapeutic effects of OXT in reversing isolation-induced neuropsychiatric disorders and elucidates its potential regulatory mechanisms, offering important implications for clinical interventions." https://t.co/hXkWRD1gMV
Create Safety, Let Mentees Seek Solutions, Not Answers
The hardest part of mentoring someone you believe in is holding back the answer to a problem they have not finished solving yet. The real work is creating enough safety that when they are ready, they come to you to...
Use Bonus Scenes to Grow Your Author Newsletter
How to build a newsletter when you’re just starting as an author… I will always suggest adding bonus scenes to the end of your books to newsletter build. It builds your list with organic, already invested readers… But what if...
SNY's Atopic Dermatitis Candidate Fails; NKTR Rem
$SNY next-gen atopic dermatitis drug failed in P2b. Missed primary endpoint. MOA was IL13xTSLP. Now what have they got to follow up dupi if (when?) they discontinue amlitelimab? $NKTR 👀 🤷🏻♂️ Remains the only new MoA...

Longevity Hack: Rotate Veggies Using a Calendar
Seeking longevity? Forget risky and unproven biohacks. Stick with proven, common-sense solutions. Here's a tip I give my family office and concierge medicine patients: Use a calendar and rotate through various veggies. Why?
Chad Gilbert Turns Cancer Struggle Into Musical Hope
Chad Gilbert talks turning cancer struggles 'into something positive' on latest New Found Glory record https://t.co/YcsTGxrVlJ

Stay Grounded Amid Rapid Bioinformatics Advances
🧵Bioinformatics evolves fast. New tech. New data. New analysis. But here's how to stay grounded and not get overwhelmed: https://t.co/VdWFpeE93W
Flatiron Building's First Luxury Condo Listed at $58.5M
It's a new day at the #FlatironBuilding, as handsome 20th century #landmark begins its new life as lux #condos. 1st unit goes, entire 21st floor, w/had a $58.5M ask. #OlshanReport #NYC #FlatironDistrict #realestate #CRE #23skiddoo #mortgage https://t.co/oqZffAFrR3

From Giants' Shoulders to Moon's New Foundations
Your whole life you hear about the shoulders of giants. Then one day you wake up and find you're the shoulders. Four broad new sets of shoulders just orbited the Moon. Imagine how many more will stand upon them. nasa canadianspaceagency #Artemis
Avoid AI Travel Scams: Safe Workflow for Solo Travelers
AI and Travel Scams: How Solo Travelers Get Tricked (and What a Safe Workflow Looks Like) https://t.co/9HesntfEdL #solotravel #solotraveler #solotraveling #travelingsolo #travelingalone #travel

Cursive Writing Sharpens Focus and Memory in Digital Age
Most of our work today happens on screens. We type, switch between tools, and handle constant input. It's efficient, but it often comes at the cost of focus and depth of thinking. I started noticing this in my own work. I...
Apology Doesn't Equal Change: Skill Still Developing
Say it with me: My child repeating the same behavior after a genuine apology is not proof they don't care. The remorse was real. It just means the skill isn't fully developed yet.
Cut the Nonessential, Gain Time and Tranquility
"Most of what we say and do is not essential. If you can eliminate it, you'll have more time, and more tranquility. Ask yourself at every moment, "Is this necessary?" -Marcus Aurelius
Stop Perfecting: Ship 80% and Scale
Most agency owners don’t delegate because they think nobody can do it like them. Perfection is the most expensive thing in your agency. Every hour you spend polishing something from 80% to 100% is an hour you’re not spending on the...
Neutral Atoms Become Second‑largest Qubit Platform by Company Count
neutral atoms are now officially the second most competitive qubit platform out there in terms of numbers of companies… with at least one more company in stealth. https://t.co/XoL1yY1JY2

Plans Are Starting Points; Embrace Pivots for Growth
38 🎂 At 20 I had a plan for my life. It bore almost no resemblance to what actually happened. Here is what I know at 38 that I didn’t know at 20. The plan is useful for getting started, but it...
U2’s Preloaded iPod Album Was Surprisingly Great
Perhaps my hottest take is that the U2 album that came pre-loaded on the iPod ages ago was actually...pretty darn good.

Their Brief Comments Don’t Define You—Stay Liberated
People worry about their own stuff, they may pause for a second and make a comment about yours .. but it’s for a second .. they’re in their own world and their own shit .. and that should liberate...

Science Provides Incremental Evidence, Not Absolute Truth
Scientific findings are often presented as conclusive "when in reality they represent incremental evidence within a larger, uncertain body of work. A single study cannot establish truth; at best, it shifts probabilities" ht @ProfNoahGian https://t.co/V4FSnNTHOi https://t.co/kdOnLWm9xl

Higher Protein Intake Reverses Sarcopenia in Elderly Women
As a medical school professor, the protein recommendation I was taught -- 0.8 g/kg body weight -- is actively harming older adults. New data proves it. A 2025 Frontiers in Nutrition trial randomized 126 elderly women with sarcopenia into two groups...

Mental Models: Essential Tools for Agribusiness Success
Mental Models for Agribusiness Leaders ◼︎◼︎◼︎ Recently, I talked with @timhammerich on The Future of Agriculture, one of my most listened to podcasts. It was a ton of fun to join Tim and talk about some of the concepts that have been...

Ultra‑processed Foods Hijack Brain Reward Like Cocaine
As a medical school professor, I have to be blunt: ultra-processed food is not just unhealthy. It is neurologically addictive. A February 2026 review in Pharmacological Research analyzed neuroimaging and molecular data and concluded: -- Ultra-processed foods activate the same dopamine reward...

Kindness Is the Top Proven Boost to Wellbeing
"We scientists have found that doing a kindness produces the single most reliable increase in wellbeing of any exercise we've ever tested." Martin Seligman, Psychologist and Educator 💙 #tuesdaythoughts #quote #psychology #HealthCoach #Kindness #BeKind #KindnessMatters https://t.co/4ehUm4JjKw
Celebrate Restaurant Regular Perks with Recipe and Q&A
The joys of being a restaurant regular. Plus, a recipe for a classic salad and a Q & A with a Washington notable. You'll find it all in my "Next Course" newsletter https://t.co/cU655CHjec via @tomsietsema

The Vagus Nerve: Your Body’s Hidden Lifespan Connector
What if one small nerve quietly connects your brain to your heart, your gut, your immune system — and even how long you live? That was the question I brought to Dr. Elisabetta Burchi, a clinical psychiatrist, neuroscience researcher, and Head...
Shift Focus From Habit to Underlying Energy
To change your relationship with something (whether it’s alcohol, sugar, shopping or scrolling) instead of focusing on the behaviour, look at the energy behind the behaviour. It’s not about the ‘thing’. It’s about your relationship to the thing.

Exercise Cuts Visceral Fat, Boosts Insulin Sensitivity in NIDDM
Mobilization of Visceral Adipose Tissue Related to the Improvement in Insulin Sensitivity in Response to Physical Training in NIDDM: Effects of branched-chain amino acid supplements 🔘"Patients who exercised increased their VO2 peak by 41% and their insulin sensitivity by 46%... 🔘with a...
India Leverages Thorium to Outlast Global Uranium Limits
India has ~2% of global uranium but ~25% of thorium. What was once a weakness became a strategy. In the 1950s, Homi Bhabha designed a 3-stage program: • Uranium → Plutonium • Plutonium → Breeds more fuel • Thorium → U-233 India holds ~846,000 tonnes of...

Sarcopenia Doubles Death and Disability Risk in Seniors
As a medical school professor, I can tell you the most dangerous disease you have never heard of is sarcopenia -- and a massive new meta-analysis just proved it. A 2026 Frontiers in Nutrition review of thousands of community-dwelling older adults...

Four‑Month MDF Cuts NAFLD Liver Fat by 24%
"The 4-month intervention with this MDF was effective in reducing IHTC in patients with NAFLD by an absolute reduction of −5.89% and a relative reduction of −24.30% after adjusting for weight loss. Such effect was partly mediated by altered composition...

Exploring Charlie Constantinou’s Natural Dyes and Tailoring Revival
I’ve always been curious how charlieconstantinou achieves these natural and earthy looking colours that I don’t usually see on garments, so I had to ask about the dyeing process. I was also great to see the increased tailoring focus this...
True Confidence Is Resilience, Not Guaranteed Victory
Nobody tells you this: Confidence is less about knowing you’ll win and more about knowing you’ll bounce back even if you don’t. Real confidence is resilience. Adaptability. Tolerance for uncertainty. Fear loses when you know failure is never final.

Essential Nutrition Blueprint for Your Fight Camp
The complete guide to plan your fight camp nutrition This will help so many of you 🤝 So make sure you hit save or send to a team mate who needs it 📲
Test Your Physiology, Train at the Right Intensity
Physiological testing isn’t about geeking out on numbers. It’s about *intensity discipline*... Knowing where you should be training & sticking to it! I spent years training at the wrong intensity. And it was my ultimate limiter.