Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
The FDA released draft guidance that lets biosimilar developers use foreign comparator data and, in some cases, replace clinical studies with chemical analysis, potentially cutting development costs by $20 million. Simultaneously, the agency launched the Adverse Event Monitoring System (AEMS), a unified platform that will publish roughly 6 million adverse‑event reports in real time, consolidating seven legacy databases. Additionally, attorneys general from 25 states filed a motion to join a lawsuit challenging the EPA’s decision to rescind the 2009 climate endangerment finding, underscoring a growing legal pushback on federal climate policy.
1. #Measles update: The total confirmed cases so far this year has risen to 1362 as of 3/12. Key context: The 2026 total to date is 60% of the 2025 total for the entire year. #CDC reports that among cases with...
The J. Craig Venter Institute unveiled a 4D, nanoscale simulation that tracks the entire life cycle of a minimal bacterial cell, marking a milestone for synthetic biology. A new gene‑editing platform designs DNA donors that dodge immune detection, enabling safer,...
The latest ASCO GU strategic intelligence report spotlights renal cell carcinoma (RCC) as a field entering a transformative phase. Analysts highlight emerging biomarkers, novel HIF‑2α inhibitors, and evolving immunotherapy combinations as potential high‑impact developments. While these advances promise to reshape...
BlackDoctor, a Black‑owned health media brand, has launched BlackDoctor Pro, a dual‑platform clinical delivery model that equips providers with culturally fluent data and AI tools. The rollout adds a network of more than 20,000 practitioners, a proprietary AI assistant called WellBot,...
Serotonin Centers announced the Serotonin Partner Program, a medical longevity model for U.S. fitness facilities. The turnkey platform lets gyms add medically supervised services—weight loss, hormone optimization, peptide and NAD+ therapies, IV metabolic support—within dedicated longevity suites. Serotonin funds, staffs,...
Insulet announced a recall of select Omnipod 5 insulin patch pumps after discovering a small tear in the internal tubing that can cause insulin to leak inside the pod. The defect has been linked to 18 serious adverse events, including hospitalizations...
China’s National Medical Products Administration has granted the first commercial approval for an invasive brain‑computer interface, developed by Shanghai‑based Neuracle Medical Technology. The coin‑sized, wireless implant sits on the brain’s surface and enables users with partial spinal‑cord injuries to operate...
Jackson Healthcare president Shane Jackson was named to the 2026 Staffing 100 North America list, marking his ninth consecutive appearance. During his tenure, the company added a dozen acquisitions, broadened its portfolio to include executive search, allied health, nursing, surgical services...
CDC data show early prenatal care (first trimester) fell from 78.3% in 2021 to 75.5% in 2024, a 4% drop, while second‑trimester initiation rose 12% and late or no care increased 16% to 7.3%. The shift occurred across age groups...
A Harvard‑Tuskegee panel called for a distinct Black bioethics to confront persistent health inequities, citing the legacy of the Tuskegee Syphilis Study and the COVID‑19 mortality gap. Panelists highlighted that the Belmont Report’s safeguards have not eliminated racial disparities, with...
A new JAMA Internal Medicine study finds that the Inflation Reduction Act’s 2024 drug‑pricing provisions have reduced cost‑related medication nonadherence among Medicare beneficiaries. Compared with privately insured peers, seniors saw a 4.9‑percentage‑point drop overall and a 7.8‑point decline among those...
Western Alliance Bank announced the launch of a dedicated Healthcare commercial banking team, headed by industry veteran Jennifer Hwang. The new unit will serve subsectors such as specialty pharmaceuticals, medical devices, home health, hospice, and ambulatory surgical centers. Leveraging the...
Gubra, a 300‑employee Danish biotech known for its obesity drug partnerships, announced plans to adopt a Roivant‑style incubation model. The strategy will spin out a series of focused biotech companies, each targeting niche therapeutic areas beyond obesity, such as metabolic...
Researchers have developed a self‑amplifying RNA injection that directs skeletal muscle to produce the heart‑healing peptide Nppa, dramatically reducing scar formation in pig models of myocardial infarction. The lipid‑nanoparticle‑delivered RNA sustains protein expression for at least four weeks, far outlasting...
Aditxt, Inc. announced the acquisition of Ignite Proteomics for $36 million in Series A‑2 convertible preferred stock, adding a CLIA‑certified functional proteomics platform to its oncology portfolio. Ignite’s Reverse Phase Protein Array (RPPA) assay quantifies 32 phospho‑ and total‑protein biomarkers, offering therapy‑selection...
The National Joint Registry (NJR) issued a formal response to a BMJ article that incorrectly claimed the new Zimmer Biomet bone cement had been evaluated using NJR data. The NJR clarified that the cement has not yet been used in the...
DelveInsight’s new report projects the global diagnostic imaging equipment market to expand from $51.5 billion in 2025 to $82.2 billion by 2034, implying a roughly 5% compound annual growth rate. MRI systems emerge as the largest product segment, while North America retains...
Peptide therapeutics are powerful. But making them has always been difficult. Traditional chemical synthesis can involve long routes, poor selectivity, and significant environmental impact, while biological production is often limited by the pathways evolution happened to provide. What if we could design...
Guardant Health released a Harris Poll showing 92% of Americans aged 45+ support no‑copay coverage for blood‑based colorectal cancer (CRC) screening. The survey highlighted anxiety around colonoscopies and disgust for stool tests as major barriers, while 77% said a FDA‑approved...
The 2018 heart‑allocation reform removed rigid donor service areas, shifting the primary barrier to transplantation from geography to a center’s ability to deploy modern donor‑utilization tools. Advanced preservation technologies and donation‑after‑circulatory‑death (DCD) protocols have expanded the donor pool, but adoption...
Researchers identified a high‑altitude Retsat Q247R mutation that enhances myelin formation under hypoxic stress and accelerates remyelination in mouse models. The variant boosts neuronal production of the vitamin‑A‑derived metabolite ATDR, which activates the RXR‑γ pathway in oligodendrocyte progenitors. Administering ATDR...
Immutep’s LAG‑3 fusion protein eftilagimod‑alpha failed to improve overall survival in a Phase 3 randomized study in non‑small cell lung cancer. The trial, enrolling roughly 600 patients, did not meet its primary endpoint and showed no statistically significant benefit versus standard...
Ontario Shores Centre for Mental Health Services implemented a near‑real‑time analytics platform to anticipate and manage behavioral health issues. The system leverages AI‑driven predictive models that analyze patient data streams, flagging risk factors before crises occur. This proactive approach cut...
Merkel cell carcinoma log, day #594. Yesterday, I was at Dana-Farber for my first infusion of avelumab in more than 3 months. Aside from two botched blood tests — the buzz is the blood tests are being done with recently...
The Washington Senate voted 30-19 to approve amendments to S.B. 5847, sending the bill to Governor Bob Ferguson. The legislation lets network providers deviate from Department of Labor and Industries (L&I) coverage decisions and national treatment guidelines when medically appropriate....
Boston Micro Fabrication (BMF) showcased a dual‑resolution 3D printer capable of producing functional parts with tolerances in the tens of microns—smaller than a human hair. CEO John Kawola explained how the machine alternates between macro and micro modes, delivering both...
The Defense Health Agency will resume billing civilians for care at military treatment facilities after a three‑year pause, affecting an estimated 137,000 non‑beneficiary patients who received emergency or trauma services since June 21 2023. A new Military Health System Modified Payment and...
Ultragenyx announced that its investigational gene therapy for ornithine transcarbamylase (OTC) deficiency met a primary endpoint in a Phase 3 trial involving 37 patients. The study demonstrated a statistically significant reduction in blood ammonia levels, the key marker of disease...
Doctors at three Irish acute hospitals performed four wrong‑site surgeries in the past two years, including an operation on the wrong testicle. The incidents involved a testicle, a leg, oral structures and another genital organ, prompting criticism from patient advocates....
Colorectal cancer remains a major global health burden, with over 1.9 million new cases and 900,000 deaths in 2022, placing it high on biotech priorities. Treatment has shifted from surgery‑centric approaches to a blend of refined chemotherapy backbones and biomarker‑driven targeted...
Artificial intelligence is moving beyond paperwork in palliative care to assist clinical decision making. A 2025 market survey shows 53% of providers use AI for documentation, while 19% employ predictive alerts. PalliCare’s integration of athenaOne’s Patient Summary feature aggregates ambient...
Ambulatory surgery center (ASC) projects typically span 18‑24 months and succeed when early decisions are anchored to a clear purpose. Medline’s eight‑phase, “why‑first” framework ties feasibility, design, licensure, staffing and technology to concrete workflow outcomes before the first case. A...
Chapters Health System, the nation’s largest nonprofit hospice network, is deploying AI, automation, and data analytics to overhaul its revenue cycle management. An AI-driven chart review tool now scans clinical documentation in real time, automatically routing missing signatures or data...
Hospice utilization for cardiovascular disease patients remains low, with cardiac cases representing just 12.7% of hospice admissions in 2024. Dr. Heather Veeder of VITAS Healthcare cites prognostic uncertainty and delayed goals‑of‑care conversations as primary reasons patients enter hospice later than...
On @fox5ny with @stevelacy and natashacurrytv discussing the very real connection between sleep apnea and heart disease. There may be a drug therapy on the horizon to free us of the clap machine. @helloheartapp @morehouseschoolofmedicine mag1849_ medical_association_of_atlanta
The Coronary Artery Calcium Scan - The Heart Disease Test You've Never Heard Of There's a 5-minute heart scan… No needles. No treadmill. No contrast dye. And it predicts heart attack risk better than cholesterol alone. https://youtu.be/XVNLubDAE-M
BrightSpring Health Services agreed to sell its ResCare Community Living unit to Sevita for $835 million in cash, but the Federal Trade Commission initially blocked the transaction on antitrust grounds. The FTC later cleared the deal after BrightSpring and Sevita consented...
On the clock: The White House has until 3/25 to nominate a new #CDC director. The Federal Vacancies Reform Act states a job like CDC director can only be filled on an acting basis for 210 days from the creation...
With FDA go ahead, a China #biotech notches a first in cell therapy testing https://t.co/QorwJmou8w by @realJacobBell $XENE $BHVN
Cancer vaccines are showing marked efficacy vs refractory cancers and are going to be part of the future Rx armamentarium. Beyond that, ultimately, for prevention in high-risk individuals. A new stellar review @NatureMedicine https://t.co/PhtdZDtSBl https://t.co/okmwCD8AyB
Lasting improvement doesn’t come from dashboards or mandates. It comes from clinicians who trust the data and own the change. A great conversation on what really works. 👉 https://t.co/SwV5qc59SV @HealthCatalyst #clinicalimprovement #HITSM
It is not clear to me how denying diagnosis to adults like me would get children more medical help.
100 brain microhemorrhages in a patient with cerebral amyloid angiopathy and 2 copies of APOE4 after amyloid antibody therapy https://t.co/ASpVuijFNW https://t.co/hdtwtv1usq
NEW: Another failure in the clinic in the world of LAG-3, a target once seen as possibly the next major checkpoint inhibitor after PD-1 and CTLA-4. My latest on Immutep's Phase 3 disappointment, as LAG-3 focus now shifts to a...
@angelazhay - I'd be keen to make contact with you to discuss NHS waiting lists for a piece I'm working on. Could you reach me on laura.donnelly@telegraph.co.uk?
The reactivation of herpes simplex virus (HSV-1, not only herpes zoster) may be tied to accelerated aging and dementia, and account in part for the mechanism of Shingrix vaccine''s protection @WIRED https://t.co/iKF1JcYSu0
Evotec, Vistagen lay off staff; Immutep shares collapse on study failure https://t.co/OikmCdJ6sg $EVO $VTGN $IMMP - 81% $RARE $ATRA
“We’re just kind of done with the vaccine issue,” said one White House official. “We’ve done what we want to do on the vaccine front.” On the future of the MAGA-MAHA alliance, w/ @ChelseaCirruzzo https://t.co/g6goE2TC6e
Spending on healthcare services is up 7.9% year over year, far higher than the inflation rate reported in the CPI https://t.co/Mt0STaWkJz
