Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves first CIRM‑funded gene‑editing therapy for rare immune disorder
The FDA has granted approval to KRESLADI, a gene‑editing therapy from Rocket Pharmaceuticals that treats severe leukocyte adhesion deficiency‑I in children without a matching bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine (CIRM), highlighting the agency’s impact on translational research.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Colombo & Hurd secured an EB‑2 National Interest Waiver for a Colombian neurologist specializing in Alzheimer’s disease, enabling him to expand affordable, non‑pharmacologic care in underserved rural U.S. communities. The petition was approved in just three days with premium processing and no Request for Evidence. The case hinged on demonstrating that his interventions have nationwide relevance beyond his current hospital employer. USCIS recognized the work’s alignment with public‑health priorities such as early dementia detection and caregiver support.
Stanford researchers engineered natural killer (NK) and cytotoxic T cells to overexpress metabolite‑sensing G protein‑coupled receptors, most notably GPR183, enabling the cells to home toward tumor‑derived metabolic cues. In mouse models of triple‑negative breast and ovarian cancer, GPR183‑enhanced NK‑92 cells...
Alamar Biosciences, the Fremont‑based proteomics company, filed to go public on Nasdaq after raising $128 million in a Series C round and adding almost 100 employees in two years. The move marks the firm’s transition from research‑focused labs to commercial sales of...
Digital health startups raised $14.2 billion in 2025, a 35% increase from the prior year, with AI‑enabled companies capturing 54% of the capital and enjoying a 19% premium on deal size. The surge is reshaping venture strategies as investors chase AI‑driven...
A new longitudinal study of 4,015 Chinese adults aged 45 and older shows that adverse childhood experiences dramatically increase the likelihood of developing both clinical depression and a chronic physical disease later in life. Participants with four or more childhood...
Perimenopause is not a gynecologic problem. It’s a cardiovascular turning point, and we’ve been treating it like a nuisance symptom. In fact, I’ve been teaching this in a deeper way lately, and the response has been eye-opening. The most dangerous...
Roxana Mehran, MD, an interventional cardiologist and professor at Icahn School of Medicine, began her one‑year term as president of the American College of Cardiology (ACC) at the ACC.26 conference in New Orleans. Mehran, a recognized leader in women’s heart health,...
Three Minneapolis‑area medtech startups—Person Health, Vail Scientific, and Peytant Solutions—will present technical talks at DeviceTalks Minnesota on May 4. Person Health is developing graphene‑based nanosensors for a non‑invasive breath test that detects early‑stage lung cancer. Vail Scientific offers a handheld breath...
Genetically modified pig livers have entered early clinical testing, with a Chinese patient surviving 171 days after transplantation. Researchers in China are exploring pig livers as auxiliary support, while a University of Pennsylvania team is evaluating extracorporeal pig livers as...
In this episode, Unity Stokes talks with Kim Fisher, Chief Impact Officer of Startup Health’s Food is Medicine Moonshot and Program Director of UC Davis’s Innovation Institute for Food and Health, about the rapid emergence of the food‑as‑medicine movement. Fisher...
The Aston Ambulance Authority launched a 24/7 paramedic service on March 24, covering Aston Township, Lower Chichester, Trainer and Marcus Hook. The new operation employs 17 paramedics, an EMS chief and a medical director, filling the pre‑hospital care void left by the...
Ensemble, a leading revenue cycle management provider, and Cohere are expanding their partnership to create the healthcare industry’s first RCM‑native large language model. Unlike generic LLMs that rely on heavy prompt engineering, the new model is fine‑tuned from scratch on...
The UK Department of Health and Social Care released a new Pandemic Preparedness Strategy that shifts pandemic planning from a reactive stance to a standing policy priority. It calls for scalable diagnostic capacity, stronger supplier resilience, and expanded strategic stockpiles,...
Revenue cycle is the invisible backbone of every health system. It's finally getting the attention it deserves. New episode of Lifers this week: I sat down with Terri Meier (Assistant Vice Chancellor for Revenue Cycle at UAMS, 43-year industry veteran) live...
Oliver Robinson’s November 2023 suicide prompted a Manchester coroner to conclude that his privately prescribed medicinal cannabis probably contributed to his death. The inquest highlighted failures at Curaleaf Clinic, including reliance on outdated records and lack of coordination with NHS providers....
The FDA’s Center for Drug Evaluation and Research (CDER) has announced a slate of senior leaders, including Tracy Beth Høeg as Acting Director and Michael Davis as Deputy Center Director. The roster adds specialists overseeing regulatory policy, rare‑disease strategy, substance‑use...
Elecoglipron (ECC5004/AZD5004), an oral small‑molecule GLP‑1 receptor agonist, completed Phase 2 trials in type 2 diabetes and obesity, meeting primary endpoints in the SOLSTICE and VISTA studies. AstraZeneca licensed global rights from Eccogene for an upfront payment of $185 million and potential milestones...
Rep. Ryan Mackenzie (R‑PA) is drafting the Data Driven Suicide Prevention and Outreach Act to fund AI‑driven predictive‑model grants for veteran suicide prevention. The bill would award one grant per each of the VA’s 18 Veterans Integrated Service Networks, targeting...
Mark Cuban has thrown his weight behind the Senate’s Break Up Big Medicine Act, which seeks to separate insurers, pharmacy‑benefit managers and providers that are currently owned by the same conglomerates such as UnitedHealth Group. The legislation would bar parent...
Cold Chain Technologies (CCT) announced a formal pledge to achieve net‑zero global emissions by 2050, focusing on Scope 3 emissions that represent roughly 80% of a pharmaceutical company’s carbon footprint. The company has already reduced landfill waste by 147 million lb, surpassing its...
Jimini Health, a New York‑based behavioral health startup, announced a $17 million seed round, bringing its total capital to more than $25 million. The funding, led by M13, Town Hall Ventures and Zetta Venture Partners with backing from former CMS Acting Administrator...
ImmunityBio secured $75 million of non‑dilutive financing under its existing royalty‑interest purchase agreement with Oberland Capital, raising total committed capital to $375 million. At the same time, Nant Capital converted $25 million of debt into common stock, reducing the company’s liabilities. The combined...
Canadian researchers found that adults with end‑stage kidney disease experience a rebound in employment earnings after receiving a kidney transplant. Mean annual income rose from roughly CAD $45,600 (≈ $33,700 USD) in the transplant year to CAD $52,900 (≈ $39,100 USD) three years later, a gain...
In 2025, 68% of real‑estate investors increased their healthcare allocation, driving roughly $12.5 bn into the care‑home sector, which represented 79% of all healthcare investment. The surge was anchored by Welltower’s $6.5 bn purchase of Barchester Healthcare and a $1.5 bn acquisition of...
The 8 Biggest Healthcare Technology Trends To Watch In 2026 Healthcare is being transformed by AI, digital twins, personalised medicine and advanced diagnostics — all driving more proactive, efficient and patient-centred care. Read more 👉 https://lnkd.in/e86HpWFZ #Healthcare #HealthTech #AI #BernardMarr
The number of 100+ year olds in Okinawa has increased by 4283% from 1975 1975: 29 centenarians 2021 peak: 1271 centenarians Okinawa’s longevity story is generation-specific: people born before WWII had a clear mortality advantage While post-WWII cohorts have had worse mortality than mainland...
Republicans in the House are proposing to pull roughly $30 billion from federal health‑care subsidies to fund President Trump’s expanded Middle‑East war and a simultaneous ICE expansion. The plan would strip coverage from an estimated 300,000 Americans, bundling three politically sensitive...
This is a very important study and I'm hearing from clinical experts in my network that the best prevention is calcium, weight bearing exercise and getting regular DXA Scans. Otherwise we're going to see a big increase in high-cost orthopedic...
Healthcare organizations are evaluating endpoint hardware to unlock AI‑driven efficiencies, weighing thin clients, traditional PCs, and emerging AI‑optimized workstations. Thin clients offer low power consumption, centralized management, and longer refresh cycles, while AI PCs deliver on‑device neural processing at a...
AI Med Consult and 4th Dimension EMR announced a strategic partnership at the AACS Annual Scientific Meeting, integrating AI‑driven patient engagement tools with 4D EMR’s aesthetic‑medicine platform. The combined solution will feed real‑time interaction data into electronic medical records, delivering...
Bristol Myers Squibb announced the evolution of its Standing in the Gaap program, expanding its reach to address equity gaps in multiple myeloma care. The initiative will launch one of the largest U.S. multiple myeloma surveys, targeting more than 1,000...
Millions of Americans sustain concussions each year, yet up to half remain unreported and untreated. Dr. Al Cobb highlights five essential updates for providers: recognizing concussion as a brain‑wide and cervical injury, abandoning prolonged dark‑room rest, integrating graded exercise and...
Maxwell TEC’s product director Andrew O’Connell discusses how home‑care communication is evolving from simple reminders to AI‑driven, relationship‑based messaging, with SMS as the core channel for older adults. He explains that the company’s nanaCONNECT platform combines automated, context‑aware texts with...
Artificial intelligence is reshaping clinical development by augmenting, not replacing, human expertise. AI already accelerates medical imaging, compound discovery and COVID‑19 vaccine modeling, compressing timelines from years to months. In clinical outcome assessment (COA) translation, AI can support draft translation...
Avo, a clinical AI platform that overlays major EHRs, closed a $10 million Series A led by Noro‑Moseley Partners and backed by AlleyCorp. The company announced a strategic partnership with EBSCO’s DynaMed to embed evidence‑based guidelines directly into its AI copilots. Avo’s...
Canada’s federal government has earmarked nearly $1.4 billion for Indigenous health and wellness, with $168 million for urban programming, $630 million for mental‑health initiatives, and $592.4 million for assisted‑living services. The investment aims to deliver culturally grounded care to over a million urban Indigenous...
Researchers have demonstrated that a simple musical intervention during surgery can markedly lower patients' blood pressure, heart rate, and postoperative pain, underscoring the powerful heart‑brain connection. The findings suggest everyday practices that align cardiac and neural rhythms could become a...
Mayo Clinic and Wayne State scientists report that post‑menopausal women who combined tirzepatide with hormone therapy lost 35% more body weight than those on tirzepatide alone. The retrospective analysis of 120 women showed an average 19.2% loss versus 14%, prompting...
The FDA issued a warning letter to Henan Lvyuan Pharmaceutical after a September 2025 inspection uncovered multiple Current Good Manufacturing Practice (CGMP) violations. Inspectors cited severe facility maintenance issues, including corrosion and water leaks that could compromise API potency and...
The FDA issued Warning Letter 320‑26‑53 to Microbiological Testing & Consulting, LLC after a September 2025 inspection uncovered multiple Current Good Manufacturing Practice (CGMP) violations. The firm failed to maintain adequate laboratory controls, documentation, media qualification, and a functional quality‑control unit,...
Patient‑provider communication gaps—language barriers, hearing loss, rushed visits, and limited empathy—continue to jeopardize care quality and increase legal exposure. The National Institute on Deafness and Other Communication Disorders reports that 22% of adults 65‑74 and 55% over 75 suffer disabling...
Researchers used transcranial ultrasound to stimulate the amygdala during a fear‑conditioning experiment, finding that participants learned fear more slowly and extinguished it faster. The breakthrough suggests a drug‑free tool for anxiety, PTSD and self‑mastery.
Kain Capital has completed its acquisition of White Wilson, a move that adds a new platform company to its healthcare and life sciences holdings. The transaction, whose financial terms were not disclosed, signals continued consolidation in the private‑equity‑driven health sector.
The FDA’s recent “green list” designation has cleared more than 50% of Chinese manufacturers of GLP‑1 obesity drugs, effectively handing China a dominant role in the U.S. supply chain. Critics warn the move could expose American patients to substandard products...
American medicine is moving from an expansion mindset to confronting permanent resource constraints driven by workforce shortages, supply‑chain fragility, climate impacts, and rising costs. The pandemic stripped away safety buffers, exposing the need for systemic redesign rather than incremental cost‑cutting....
On February 19, 1994, 31‑year‑old Gloria Ramirez was taken to Riverside General Hospital, where attempts to treat her triggered a baffling incident that sickened 23 of the 37 emergency‑room staff. Investigators later suggested that dimethyl sulfoxide (DMSO) from a pain‑relief cream reacted...
Natera’s Signatera circulating‑tumor DNA test was shown in a prospective Clinical Cancer Research study to identify older women (≥70) with early‑stage ER⁺/HER2‑ breast cancer who can safely forgo surgery and remain progression‑free on primary endocrine therapy. Baseline MRD‑negative patients (68%...
IKS Health, a global care‑enablement leader, has acquihired AI‑native startup ThinkDTM, bringing its entire engineering team into the firm. Founder Tij Bedi will join IKS as Executive Vice President and General Manager of Patient Access and Innovation. The new unit...
The FDA issued a drug safety communication warning that Tavneos (avacopan) is linked to 76 post‑marketing cases of drug‑induced liver injury, including eight fatalities. Seven patients developed biopsy‑confirmed vanishing bile duct syndrome, a severe cholestatic condition, with three deaths. Median...
The CARES Act, enacted in March 2020, added new authorities to the FDA to curb drug shortages by requiring manufacturers to notify the agency of permanent discontinuances and production interruptions. It also mandates the creation of site‑specific risk‑management plans and...
