
Astronomers have identified a planet 35 light‑years away that does not fit existing small‑planet categories. The world, L 98‑59 d, was first discovered in 2019 and observed by JWST in 2024 and ground facilities in 2025. Researchers used computer models to simulate five billion years of mantle activity, revealing a composition unlike rocky gas dwarfs or water‑rich ocean worlds. The findings, published in Nature Astronomy by an Oxford‑led team, propose a new class of exoplanets.
Ionis Pharmaceuticals announced that its Phase 1/2a PrProfile trial of ION717, the first PrP‑lowering antisense oligonucleotide for symptomatic prion disease, has reopened with a third dosing regimen. The study, which enrolled 56 patients in 2024, will now recruit at three...

A recent study of Japan’s national COVID‑19 surveillance data from 2020 to 2025 reveals a consistent pattern of two annual epidemic peaks—one in summer and another in winter—beginning in 2022. The analysis shows that these surges occurred despite the country’s...

A recent MRI study found that long‑term Buddhist insight meditators exhibit a thicker cerebral cortex and a slower rate of cortical thinning compared with non‑meditating controls. The research suggests that sustained attention to breath and present‑moment awareness may counteract typical...
Researchers have mapped how senescence spreads between human brain cell types via the senescence‑associated secretory phenotype (SASP). Using DNA‑damage‑induced cultures and conditioned‑media assays, they identified cell‑type‑specific SASP signatures that drive secondary senescence in neighboring astrocytes, endothelial cells, microglia, oligodendrocytes and...
Materials scientists at Nanyang Technological University have created the world’s first sunscreen made from Camellia flower pollen. Laboratory tests show the pollen microgel blocks UV rays with SPF 30, comparable to titanium dioxide and zinc oxide formulations, while also keeping skin...

Early 2025 the Trump administration terminated the National Nature Assessment, labeling it wasteful and ideologically driven. In response, more than 170 scientists produced the independent 868‑page Nature Record, funded privately with $3 million and overseen by the National Academies. The report...
Dale T. Andersen returned from the first of two 2026 astrobiology dives beneath Lake Untersee’s thick ice sheet in Antarctica. The expedition showcased the striking visual beauty and technical rigor of sub‑ice exploration, using a Kirby Morgan Exo‑26 full‑face mask, tethered safety lines,...

Researchers published in Aging Cell report that vascular injury induces misshapen nuclei in smooth muscle cells, accelerating cellular senescence. Human femoral arteries post‑angioplasty and rat carotid injury models both displayed nuclear dysmorphism linked to prelamin A buildup. The study identifies...

Recent research highlights the microvasculature as a central driver of human aging, with capillary rarefaction, endothelial dysfunction, and glycocalyx degradation limiting oxygen delivery to cells. This vascular decline triggers low‑grade hypoxia, inflammation, and mitochondrial inefficiency, linking it to age‑related diseases...

Artificial intelligence is moving from data analysis to hypothesis generation, fundamentally altering the scientific method. Recent work such as DeepMind’s GNoME system has generated millions of candidate materials, while neural networks have rediscovered physical laws without prior equations. These advances...

Researchers investigated how bubble caps thin and burst, focusing on the buoyant plumes that rise from the foot of the cap where fluid exchange occurs. In still air, these plumes appear as dark‑blue vertical columns, leading to localized thinning. Introducing...
Recent FDA approvals of resmetirom and semaglutide have shifted MASH care from a treatment‑void to a therapeutic reality, prompting sponsors to redesign trial endpoints and enrollment strategies. Non‑invasive diagnostic tools are emerging as potential primary endpoints, reducing reliance on liver...
Researchers at the Cleveland Clinic pursued fragment‑based inhibitors of SARS‑CoV‑2 NSP14, a viral exonuclease essential for replication and immune evasion. Initial crystal‑guided merges appeared active in a biochemical assay, prompting optimism about fragment linking. Subsequent resynthesis and rigorous purification revealed...

Australian researchers have uncovered a previously unknown sulfur‑sulfur rearrangement reaction that proceeds with minimal external input. The finding highlights the versatility of disulfide bonds, which can break and reform in response to diverse stimuli, opening new pathways for peptide, polymer...
Natera announced two peer‑reviewed studies demonstrating the clinical utility of its personalized ctDNA assay, Signatera, in anal squamous cell carcinoma and locally advanced rectal cancer. In the ASCC cohort of 84 patients, baseline negativity or clearance of ctDNA during chemoradiotherapy...

University of Minnesota scientists pinpointed structural features of the Marburg virus entry protein that make it up to 300 times more efficient at infiltrating human cells than Ebola’s. By creating a tightly controlled assay, they showed the protein binds the...
Researchers at DGIST unveiled a dual-modulated vertically stacked transistor featuring a graphene top gate and a micro‑hole bottom gate, achieving off‑state leakage as low as 10⁻¹² A. The design eliminates the need for expensive ultra‑precision alignment and operates at low temperatures,...
Researchers have shown that crystal dislocations in antiferroelectric PbZrO₃ thin films act as nucleation sites for ordered polar anti‑hedgehog lattices. Using atomic‑resolution TEM and phase‑field modeling, they demonstrated that electrostrictive and flexoelectric coupling at dislocation cores generates local electric fields...
A team from Monash and Deakin Universities demonstrated that silicon nanotube arrays can deliver functional mRNA into human induced pluripotent stem cells (hiPSCs) with transfection efficiencies between 55% and 64%. By redesigning nanotube geometry, using low‑molecular‑weight poly‑D‑lysine, and adjusting the...
Researchers at DGIST have demonstrated the first AI semiconductor that uses electrically controlled hydrogen‑ion migration to perform both computation and memory in a vertical two‑terminal device. The hydrogen‑based resistive switching replaces traditional oxygen‑vacancy mechanisms, delivering uniform, stable operation over more...
Researchers at University Medical Center Göttingen employed cryo‑electron tomography to capture near‑atomic structural remodeling of the mitochondrial heat‑shock protein 60 (mHsp60) under proteostatic stress. The protein reconfigures its barrel‑shaped complex, boosting folding activity and preserving mitochondrial function in stressed human...
Researchers at Pacific Northwest National Laboratory used the machine‑learning tool AtomAI to analyze atomic force microscopy images of designed protein nanoribbons on mica. The study discovered that a thin water layer on the mineral surface, not the underlying potassium lattice,...

The blog recaps the 2026 New Antibacterial Discovery and Development conference in Tuscany, where researchers presented emerging strategies against antimicrobial resistance (AMR). Dr. Quave highlighted her lab’s plant‑derived natural products targeting Gardnerella vaginalis, a key cause of bacterial vaginosis. The...
Researchers identified insulin‑like growth factor binding protein‑7 (IGFBP7) as a circulating factor that limits exercise adaptation in older adults. Plasma proteomics from a year‑long high‑intensity interval training trial showed higher IGFBP7 levels predicted smaller fitness gains. In mice, genetic deletion...
A new preprint claims a theoretical speedup for quantum factoring of large integers. Bruce Schneier, noting his lack of expertise, expresses skepticism about the result’s validity. If the claim holds, it would represent an improvement over Shor’s algorithm. The announcement...

On March 15, 2026, a citizen scientist documented Exobasidium arctostaphyli, a Basidiomycete fungus, in Monterey County, California. The observation includes high‑resolution photos but remains classified as "Needs ID" because it lacks multiple expert confirmations. The record adds a rare data...

Dorothy Hodgkin, a pioneering British chemist, earned the 1964 Nobel Prize in Chemistry while battling severe rheumatoid arthritis that had crippled her hands for over two decades. Despite limited finger mobility, she used X‑ray crystallography to elucidate the structures of...
Obicetrapib, a next‑generation CETP inhibitor, has demonstrated potent LDL‑C, apoB, and Lp(a) reductions in a large phase III lipid trial. A pre‑specified biomarker sub‑study reported a marked attenuation of p‑tau217 progression, especially among APOE4/4 carriers, hinting at a potential Alzheimer’s‑related benefit....

The article debunks three common myths about climate change: that it is not happening, that mitigation is quick, easy and cheap, and that the National Environmental Policy Act (NEPA) is the primary barrier to essential infrastructure projects. It cites recent...
Samsung Bioepis and its sister firm Epis NexLab have signed a research collaboration and exclusive license agreement with G2GBIO to develop a long‑acting semaglutide formulation using G2GBIO’s proprietary microsphere technology. The deal grants Samsung Bioepis full rights to the semaglutide...

Young meteorologist Chris Martz, dubbed the "anti‑Greta Thunberg," has transitioned from mainstream climate positions to a data‑focused stance after independent research. He now serves as a policy analyst and meteorologist for the Washington‑based Committee for a Constructive Tomorrow. Martz leverages...
Scientists have confirmed that Antarctica sits above the planet's strongest gravity anomaly, often called a "gravity hole." Using global earthquake recordings and physics‑based modeling, researchers reconstructed a three‑dimensional view of the low‑density mantle beneath the continent. The study, published in...
Researchers used machine‑learning interatomic potential (MLIP) calculations to screen dopants for orthorhombic Sn₃O₄, identifying aluminum as a stable dopant. Experimental hydrothermal synthesis confirmed the predictions, with 5 % Al‑doped o‑Sn₃O₄ delivering 16‑times higher hydrogen production under visible light. The study demonstrates...

Researchers discovered that diapausing bumblebee queens can breathe underwater, surviving up to a week submerged. The finding emerged when a lab refrigerator flooded, prompting biologist Sabrina Rondeau to investigate rather than discard the specimens. Controlled experiments with 126 queens confirmed...

On 15 March 2026, observer wandererau documented a cluster of ants in Blue Mountains National Park, New South Wales, at latitude ‑33.49028 and longitude 150.41369. The ants were identified as the double‑spined dolly ant (*Dolichoderus doriae*), but the record remains in a "Needs ID"...
Researchers have engineered hollow carbon nanoreactors with sub‑nanometer wall pores that physically trap chlorine‑electrolyte complexes inside Li‑Cl₂ battery cathodes. The 0.8 nm pores block 0.86 nm complexes while allowing lithium and chloride ions to pass, creating confined reaction chambers. This architecture delivers...

New Caledonian crows excel at the Aesop’s Fable paradigm, consistently selecting sinking stones over floating objects to raise water levels and retrieve food, achieving nearly 90% success. Laboratory trials also show they prefer solid over hollow items, higher water levels,...

Comprehensive molecular profiling of two stage IV NSCLC patients revealed distinct driver alterations—an EGFR exon 19 deletion in one and an EML4‑ALK fusion in the other—prompting personalized first‑line therapy with osimertinib and alectinib respectively. Both patients experienced rapid symptomatic improvement and enhanced...
Osaka Metropolitan University researchers discovered that the freshwater alga Trachydiscus minutus captures far‑red light by arranging ordinary chlorophyll a into large, cooperative clusters within a novel protein complex called rVCP. Cryo‑electron microscopy revealed a tetrameric architecture composed of two heterodimers that...
Researchers at Shenyang Agricultural University have demonstrated that mesopores and macropores in biochar play an active role in CO₂ capture, overturning the long‑standing view that only micropores matter. By combining theoretical models with experiments on sawdust‑derived biochar produced between 300 °C...

In 1812 Charles Redheffer debuted a claimed perpetual‑motion machine in Philadelphia, charging visitors up to five dollars to witness the supposed energy‑free device. City commissioners and later engineer Robert Fulton uncovered a hidden hand‑crank that powered the apparatus, exposing it as...
Physicists at Tokyo Metropolitan University have reported the first observation of laser‑assisted electron scattering (LAES) using circularly polarized femtosecond laser pulses on argon atoms. The measured energy and angular distributions displayed the characteristic Kroll‑Watson peaks, confirming the theoretical prediction, though...

Researchers at Parity Quantum Computing and NEC introduced a spin‑1/2 model that replaces the exponential photon‑state basis of Kerr parametric oscillator (KPO) quantum annealers with just two states per oscillator. The projection technique accurately reproduces experiments using up to ten...

Researchers at Utrecht University applied dimensional regularisation and semiclassical gravity to compute quantum back‑reaction on a timelike topological wormhole supported by an anisotropic fluid. They found that vacuum fluctuations modify the angular pressure by ±1/(8π G a L₀), which can either stabilise or...
Researchers documented a 75‑year‑old man, Doug Whitney, who carries a highly penetrant PSEN2 mutation that typically causes early‑onset Alzheimer’s disease, yet he remains cognitively normal. Imaging revealed massive amyloid buildup but tau pathology confined to the occipital lobe, an atypical...

Google Quantum AI researchers have added an inductive shunt to transmon qubits, eliminating offset‑charge sensitivity that caused measurement‑induced state transitions (MIST). The shunt provides an alternate current path, allowing dispersive readout without large detuning or extensive calibration. Tests at 10 mK...

Researchers at Aalto University and partners introduced a hybrid quantum communication protocol that merges quantum teleportation with analogue feedforward transmission. The method achieves a 3 dB fidelity gain over conventional teleportation when entanglement resources are limited and the channel preserves entanglement....

Researchers at Phasecraft Ltd and Virginia Tech used IBM’s Nighthawk superconducting processor to simulate a 10 × 10 qubit disordered Heisenberg Floquet model. They introduced a collision‑entropy metric that quantifies ergodicity within spatial patches, revealing a hierarchy where smaller regions become ergodic...

Researchers at NYU Shanghai introduced Purification Quantum Error Correction (PQEC), a technique that leverages the SWAP test to purify noisy quantum states without prior knowledge or post‑selection. The method achieves a 75% error‑threshold for depolarizing noise across any register size...