Today's Science Pulse
Cockatoos Use Peer Imitation to Boost Adaptive Vocal Skills
Researchers recorded over 2,000 calls from three Australian cockatoo populations and found that individuals who frequently mimicked flock mates expanded their acoustic repertoire. Those engaging in more peer‑copying showed higher success in responding to environmental challenges, suggesting imitation sharpens adaptation.
Australia Is Closing Its Very Large Eyes to the Universe
Australia will let its 10‑year strategic partnership with the European Southern Observatory lapse in 2027 and has decided against pursuing full ESO membership. The partnership, funded with $130 million since 2017, gave Australian astronomers preferential access to the VLT, the VLTI and the ESO Summer Programme, resulting in more than 500 proposals and over 100 refereed papers. Full membership would have cost roughly $50 million per year and opened the 30‑metre Extremely Large Telescope and ALMA to Australian researchers. Without it, Australian students face reduced telescope time, fewer collaboration opportunities, and a growing isolation from the global optical‑astronomy community.
AstraZeneca’s Breast Cancer Drug Fails to Earn Backing of FDA Advisory Committee
The FDA’s advisory committee voted against recommending AstraZeneca’s oral SERD camizestrant for HR⁺/HER2‑ metastatic breast cancer patients with an ESR1 mutation, citing concerns over the Phase 3 SERENA‑6 trial design. The study switched patients to camizestrant at the point of mutation...
Conservative Social Attitudes Are Linked to Higher Fertility Across 72 Countries, with Stronger Effects Among Women
A new study of 78,754 respondents from 72 countries finds that people who endorse more conservative social attitudes—right‑wing ideology, higher religiosity, preference for religious partners, and lower support for gender equality—tend to have more biological children. The association is modest...
BIO on the American Road Tours Gene Therapy Hub in Ohio
BIO President John F. Crowley toured Ohio on April 28, spotlighting the state’s emerging gene‑therapy hub. Researchers at Nationwide Children’s Hospital have delivered two of the FDA’s first eight approved gene therapies for Duchenne muscular dystrophy and spinal muscular atrophy type 1....
The Quiet Expert Who Stood Between Us and a Flu Pandemic
Dr. Nancy Cox, who led the CDC’s influenza division from 1992 to 2014, transformed a 14‑person unit into a global powerhouse that underpins annual flu vaccine selection and pandemic detection. She forged the WHO Global Influenza Surveillance and Response System,...
Oxford Physicists Achieve First-Ever “Quadsqueezing” Breakthrough in Quantum Physics
Oxford physicists have achieved the first experimental demonstration of quadsqueezing, a fourth‑order quantum squeezing effect, using a single trapped ion. By applying two precisely timed, non‑commuting forces, they amplified the interaction to generate quadsqueezing more than 100 times faster than...
Meltio Joins SUMMSEED Project to Develop Sustainable Medium Manganese Steel
European consortium SUMMSEED, comprising companies and universities, has enlisted Meltio to co‑develop a sustainable medium‑manganese steel for casting. The alloy is designed to lower CO₂ emissions, cut critical alloying elements, and be fully recyclable, targeting heavy‑industry sectors such as mining....
Corcept Ties ALS Drug to Improved 2-Year Survival as Phase 3 Start Date Nears
Corcept Therapeutics reported that its experimental ALS drug dazucorilant reduced the two‑year risk of death by roughly 87% in a Phase 2 extension study, despite missing its primary motor‑function endpoint. The survival benefit was most pronounced at the 300 mg dose, though...
ZettaJoule Pursues a Second Act for Japan’s High-Temperature Nuclear Reactor
Houston‑based ZettaJoule is adapting Japan’s High Temperature Engineering Test Reactor design into a 950 °C high‑temperature gas‑cooled reactor (HTGR) called ZJ0. The startup signed an MOU with Texas A&M’s Engineering Experiment Station to explore building the prototype on campus, with TEES...
MDMA-Assisted Therapy for Depression: A Promising but Early First Step
A small open‑label proof‑of‑principle study examined MDMA‑assisted therapy in 12 adults with moderate‑to‑severe major depressive disorder. Participants received two MDMA dosing sessions spaced a month apart together with nine psychotherapy sessions. At two months, 75% of participants achieved remission and...
Approaches to Reducing Toxicity and Side Effects in Cell and Gene Therapy
Cell and gene therapies are expanding rapidly, with the market projected to exceed $9 billion in 2025 and grow over 15% annually through 2035. Safety remains a hurdle, prompting multiple strategies to curb cytokine release syndrome (CRS) and related toxicities. Companies...
Aging Science Promising Yet Still Lacks Core Understanding
Aging biology is full of promise, but the reality is that it's still a nascent field. Great to be back at the @MPIAGE speaking with students and researchers about some uncomfortable truths in geroscience: We still don't understand the drivers of aging. And...
Animal Protein Edge Limited to Older Adults, Leucine Key
Our recently published meta-analysis found that animal-based proteins confer a modest advantage in stimulating muscle protein synthesis (MPS) compared to plant-based proteins (PMID: 42055214). At first glance, this might suggest a benefit to prioritizing animal protein for muscle building. However, the...
Gene Editing at Scale, Clinic Seeks Generalizable Therapies
Integrated DNA Technologies helped deliver a CRISPR therapy that rescued baby KJ Muldoon from a fatal urea‑cycle disorder, proving gene editing can correct a single disease‑causing mutation. The success highlights the field’s next hurdle: scaling personalized edits for disorders with...
Maternal Polyphenols Boost Fetal Brain Development in Rodents
New review: The effect of the mother's consumption of polyphenols (resveratrol, curcumin, quercetin, naringin, ferulic acid, genistein) on fetal neurodevelopment in rodents & improvements in brain development 🧠🧠🧠 https://t.co/xN2GISamzy https://t.co/bVFiIjoZem
RCP 8.5 Retired After Years of Implausible Climate Alarm
Back in 2019, I created a Twitter hashtag, #RCP85isBollox, to highlight the danger of building the case for climate action on a wildly implausible scenario. This month RCP 8.5 was finally retired. Read all about it... https://t.co/8grX0nacd6
Smarter AAVs Drive Gene Therapy’s Next Chapter
Gene therapy’s growth is hampered by AAV manufacturing bottlenecks, safety concerns, and high costs, prompting a wave of innovations across bioprocessing, analytics, and vector design. Companies like Thermo Fisher, PackGene, Catalent, and Asimov are deploying design‑space modeling, high‑throughput purification, and...
SpaceX Debris Inadvertently Heads Toward the Moon
SpaceX rocket set for unintentional Moon landing – well, a piece of it anyway https://t.co/9zF8XZYo8x https://t.co/1en6op55tq
What’s Next in the Evolution of Standards for Biologics Development
The United States Pharmacopeia (USP) is redefining how documentary standards support biologics, moving from product‑specific monographs toward a hybrid model that blends platform‑based chapters, emerging standards, and analytical reference materials. This shift addresses the growing complexity of monoclonal antibodies, ADCs,...
American Heart Association Unveils Lifelong Brain Health Strategy to Combat Cognitive Decline
The American Heart Association has published a comprehensive scientific statement outlining a lifelong brain‑health strategy that expands beyond vascular risk factors. The framework, released in the journal Stroke, highlights six modifiable domains—from pollution to gut health—aimed at reducing cognitive decline...
Great Lakes Cruises Blend Luxury with Science, Boost Inland Travel
Viking Cruises and American Cruise Lines have launched new Great Lakes itineraries that pair upscale amenities with hands‑on scientific programs and all‑U.S. itineraries. Viking’s 378‑guest ship offers expedition‑style voyages where passengers collect water samples, while American Cruise Lines’ 130‑guest American...
Chinese Team Sustains Tokamak Plasma for Over One Minute, a Fusion Milestone
A research team led by Prof. Xu Guosheng at the Hefei Institute of Physical Science sustained plasma for more than one minute in the EAST tokamak, demonstrating a new regime that controls divertor heat while maintaining high‑performance H‑mode without edge‑localized...
We Are Preparing to Transform the Moon and Mars. The Public Must Have a Say in This Future | Ben...
Artemis II’s successful deep‑space splashdown proved humans can travel farther than ever before and set the stage for Artemis III, which aims to land astronauts on the lunar surface for the first time in over 50 years. NASA, its international partners, and private...
How Do Close Binary Stars Form?
Roughly half of Sun‑like stars exist in binary or higher‑order systems, prompting a long‑standing debate over their origin. A new preprint by Ryan Sponzilli et al. argues that disk fragmentation—where a massive protostellar disk becomes unstable and splits—dominates the formation of...
Episode 154: Visual Navigation in Insects and Robots - Andrew Philippides
In this episode, Professor Andrew Philippides explains how studying the visual learning behaviors of ants and bees—such as learning walks and flights—can inspire efficient navigation algorithms for robots. He outlines a research pipeline that moves from field observations and panoramic...
DARPA Selects Three Companies for Lunar Orbiter Studies
DARPA has awarded Phase 1 contracts to Benchmark Space Systems, Quantum Space and Revolution Space for its Lunar Assay via Small Satellite Orbiter (LASSO) program. The mission will search for lunar water ice concentrations above 5% while operating in an ultra‑low...
New Theory Says Imagination Works by Quieting Brain Activity
A paper in Psychological Review argues that imagination sculpts mental images by silencing the brain's ongoing internal activity rather than generating new signals. The theory challenges the long‑standing feedforward model of visual processing and could reshape approaches to creativity, learning,...
Decoding Ovarian Aging to Extend Reproductive Lifespan
Ovarian aging: Mechanisms and strategies to extend reproductive lifespan Core mechanisms include genomic instability, epigenetic noise, mitochondria, inflammation, senescence & fibrosis PhD student Maria Lopez @sinclarfriends is working on it https://t.co/tuJbQb2Xcu https://t.co/K1GlXY4KsY
What Is the Kardashev Scale, and Can We Climb It?
The article revisits the Kardashev scale—a 1964 framework that ranks civilizations by their energy use—and examines why Elon Musk’s ambition to reach a Type II status may be more hype than feasible. It notes humanity is currently around Type 0.7, far from...
Study Shows Omega‑3 Supplements Boost Strength Gains in Active Adults
Researchers from the University of Greenwich and Anglia Ruskin University reported that several weeks of EPA and DHA supplementation enhanced muscle strength gains and recovery in resistance‑trained adults, highlighting a practical nutrition tool for athletes and gym‑goers.
Berkeley Scientists Pinpoint Early‑Night ‘Recovery Switch’ Driving Growth Hormone Surge
UC Berkeley neuroscientists have identified a hypothalamic circuit that ignites the nightly growth‑hormone surge during the first two‑to‑three hours of sleep. The discovery, reported in Cell, could give biohackers a new physiological window to time interventions for muscle repair, fat...
Identifying the Ages when Alzheimer’s Biomarkers Sharply Change
A Mayo Clinic Study of Aging analysis identified specific ages when Alzheimer’s disease biomarkers change sharply, using breakpoint regression on plasma proteins, PET imaging, hippocampal volume and cognition across 45‑90‑year‑olds. The most consistent inflection points clustered between 62 and 71...
Fecal Microbiota Transplantation Reduces MDM2 Expression and Risk of Liver Cancer
Researchers demonstrated that fecal microbiota transplantation (FMT) from young to old mice suppresses age‑related MDM2 overexpression and prevents liver cancer development. In the study, none of the FMT‑treated older mice developed tumors, whereas two of eight control mice did. Treated...
Deep-Earth Map Reveals a Lost U.S. Continent
The 20‑million‑dollar Magnetotelluric (MT) Array has released its final 3‑D conductivity map of the United States, revealing a massive, previously hidden crustal slab dubbed the Piedmont Resistor that stretches from Maine to Georgia. The slab, formed by volcanic activity during...
Oxidative Stress Impairs Deubiquitylase Activity in the Aging Brain
Researchers used activity‑based proteomics in mouse and killifish brains to map cysteine deubiquitylases (DUBs) across the lifespan. They found a subset of DUBs that progressively lose catalytic activity with age, despite unchanged protein levels, due to oxidative thiol modification. Antioxidant...
AI Model Outperforms ER Doctors in Emergency Diagnosis, Study Shows
OpenAI's o1 reasoning model outperformed human emergency‑room physicians in a Science‑published study, delivering more accurate diagnoses across simulated and real‑world cases. Researchers say the result underscores the power of large‑scale clinical data and advanced analytics, while warning against replacing doctors...
Park Systems Unveils NX1, First Ambient‑Condition Atomic‑Resolution AFM
Park Systems Corp. has released the NX1, a compact atomic force microscope that achieves true atomic‑resolution imaging in ambient conditions. Developed with Prof. Franz J. Giessibl, the instrument lowers the noise floor by roughly ten‑fold, bringing ultra‑high‑vacuum performance to everyday...
7 Ways To Naturally Boost GLP-1 Production & Improve Metabolism
A new review in Toxicology Reports compiles evidence that several foods and plant compounds can naturally boost glucagon‑like peptide‑1 (GLP‑1) activity, the hormone targeted by prescription drugs such as Ozempic. The analysis highlights berberine, cinnamon extract, ginger, green tea, curcumin,...
Genomics Pioneer J. Craig Venter Dies at 79, Sparking Reflection on Synthetic Biology’s Future
J. Craig Venter, the genomics visionary who helped decode the human genome and built the first synthetic bacterial cell, died on April 29, 2026, after a brief hospitalization for cancer‑treatment complications. His death, announced by the J. Craig Venter Institute,...
Fascinating New Research Suggests Artificial Neurodivergence Could Help Solve the AI Alignment Problem
A new PNAS Nexus study proposes artificial neurodivergence—deliberately designing AI agents with differing reasoning styles—as a pragmatic way to address the AI alignment problem. Researchers pitted proprietary models such as ChatGPT‑4 and Claude 3.5 against open‑source models like Mistral and...
UCI Paper Reveals How Nutrition Drives WorldTour Cycling Performance
The UCI Sports Nutrition Project paper provides one of the most comprehensive overviews of race nutrition in professional road cycling to date. This blog summarises the key insights and how nutrition science is applied in WorldTour cycling: https://t.co/xmL5ZhgcwM https://t.co/dBgaLhy5cI
Researchers Measure Overlooked Stratospheric Aerosols
In 2023, NASA’s WB‑57 high‑altitude aircraft, equipped with a custom instrument, measured aerosol particles smaller than 150 nm in the lower stratosphere for the first time. The data revealed that these ultra‑fine, organic‑rich particles dominate the surface area available for stratospheric...
How One Startup Turned Extinction Into a Multi-Billion-Dollar Science Movement
Serial entrepreneur Ben Lamm’s Colossal Biosciences, a Texas‑based de‑extinction startup, announced progress reviving the extinct Blue Buck, adding another mammal to its portfolio that already includes woolly mammoths, dire wolves and the Tasmanian tiger. The effort now spans nearly every...
Inexpensive Seafloor-Hopping Submersibles Could Stoke Deep-Sea Science—And Mining
The NOAA research vessel Rainier is deploying two neon‑lit Orpheus Ocean submersibles to map over 8,000 sq nm of Pacific seafloor at depths up to 6,000 m. Orpheus’s AUVs cost roughly $200,000 each—far cheaper than the $5‑10 million legacy vehicles—and can hop onto the mud,...
People Who Are Blind From Birth Never Develop Schizophrenia – What This Tells Us About the Psychiatric Condition
Researchers have found that individuals born blind with cortical blindness never develop schizophrenia, a pattern confirmed by a 2018 Western Australian study of half a million births where none of the 66 congenitally blind children developed the disorder. The protective...
New Genetic Discovery Could Spell This Aggressive Cancer’s Downfall
UCLA researchers uncovered a genetic weakness in small cell neuroendocrine carcinoma (SCNC) by creating prostate‑derived organoid models and running genome‑wide CRISPR screens. The screens identified the transcription factor E2F3 as a synthetic‑lethal partner of RB loss, and inhibiting E2F3 halted...
This Treatment Could Reverse Osteoarthritis Joint Damage With a Single Injection
Researchers at the University of Colorado Boulder have secured a $33.5 million ARPA‑H grant to develop a regenerative osteoarthritis therapy that could reverse joint damage with a single injection. The approach uses a controlled‑release particle system to deliver an approved drug...
Marigold Flowers Could Become a Viable Protein Ingredient, New Study Finds
University of Georgia researchers have shown that dried marigold (Calendula officinalis) flowers retain over 92% of their protein when extracted, with the albumin fraction performing on par with pea protein in water‑holding, oil‑holding, emulsification and antioxidant tests. The proteins also...
Study: Emissions and Cattle Numbers Decline at England's Farms
A Rothamsted Research modelling study finds that England’s intensively‑farmed areas cut greenhouse‑gas emissions by 18% between 2010 and 2021, alongside a measurable decline in cattle numbers. The analysis attributes the drop to tighter environmental regulations, adoption of precision farming, and...
Google Deepmind's "AI Co-Clinician" Beats GPT-5.4 in Blind Doctor Tests but Still Trails Experienced Physicians
Google DeepMind unveiled an "AI co‑clinician" that assists doctors while keeping clinicians in charge. In blind trials it beat an existing clinical AI system 67‑26 and OpenAI's GPT‑5.4‑thinking‑with‑search 63‑30 on 98 primary‑care queries, and scored 73.3% on the RxQA drug‑knowledge...