Today's Science Pulse
UK-led study reveals hidden massive star clusters deep within nearby galaxies
Astronomers using the VLA and ALMA uncovered previously unseen giant star clusters embedded deep inside nearby galaxies. The findings show that young stellar activity drives the evolution of these galaxies, reshaping their interstellar environments. Multiple observations confirm the clusters act as hidden “ring factories” of star formation.
Also developing:
By the numbers: Foundation Alloy raises $22M Series A
To Restore an Island Paradise, Add Fungi
Palmyra Atoll, a U.S. Pacific territory, has removed 1.5 million invasive coconut palms and eradicated black rats to enable native forest recovery. A new study in *Current Biology* finds rare mycorrhizal fungi living under native Pisonia trees, species unique to the atoll. Researchers suggest transplanting these fungi to boost Pisonia seedling survival, completing a restoration chain that links trees, seabirds, and coral reefs. The work highlights the critical role of underground microbes in island ecosystem resilience.
Study: Pavement Covers 40% of Phoenix
A new Arizona State University study finds that 40% of Phoenix’s land area is covered by pavement, an amount comparable to four times the size of San Francisco. Researchers highlight that asphalt emits volatile organic compounds (VOCs) that form ultrafine...
Where Brains Process Smell
Scientists have produced the first comprehensive map of smell receptors in mice, sequencing roughly 5.5 million olfactory neurons from over 300 animals. The data reveal that odor‑detecting cells are arranged in horizontal stripes across the nasal epithelium, mirroring a topographic map...
Ashvattha Therapeutics Announces Presentations Highlighting Mechanism of Action for Migaldendranib in Diabetic Macular Edema and Neovascular Age-Related Macular Degeneration
Ashvattha Therapeutics presented Phase 2 data on its subcutaneous nanomedicine migaldendranib (MGB) for diabetic macular edema and neovascular age‑related macular degeneration at ARVO. The two‑stage trial showed stable central subfield thickness for up to 12 weeks and maintained visual acuity without...
“Sidewall Symphony”
Researchers visualized the turbulent separation bubble that forms over a backward‑facing ramp—an aerodynamic feature common on aircraft—by seeding the flow with helium‑filled soap bubbles. Bright illumination caused each bubble to leave a luminous streak, producing high‑resolution images of the unsteady...
BPL-003
Great piece from @Shea_ARK "AtaiBeckley is advancing BPL-003—an intra-nasal formulation derived from 5-MeO-DMT—in treatment-resistant depression, with positive Phase 2b results supporting a Phase 3 initiation in the second quarter of 2026.[11] With FDA Breakthrough Therapy designation, BPL-003 has the potential...
Bouncing Droplet “Quantum Mechanics”
Physicists are using cheap tabletop experiments where droplets bounce on a vibrating oil bath to create macroscopic analogues of quantum phenomena. The droplets generate surface waves that act as pilot waves, reproducing effects such as quantized bound states, double‑slit interference,...
Science in Space
NASA astronaut Chris Williams and ESA astronaut Sophie Adenot conducted the DNA Nano Therapeutics‑3 experiment in the Kibo laboratory’s Life Science Glovebox aboard the International Space Station. The study explores DNA‑inspired assembly techniques to fabricate nanostructured cancer therapies such as chemotherapy and...
AIAA Public Review
The American Institute of Aeronautics and Astronautics (AIAA) has issued draft S‑159, a standard for power and data interfaces between servicing spacecraft and client space objects, and opened it for public review until 30 June 2026. The document outlines functional requirements, best‑practice...
Clinical Utility of the AITIS Model for Test-Free Identification of Sarcopenia in Patients with Stage IV–V Non-Dialysis-Dependent Chronic Kidney Disease
The study validates the Artificial Intelligence to Identify Sarcopenia (AITIS) model as a test‑free screening tool for sarcopenia in 236 patients with stage IV–V non‑dialysis chronic kidney disease. Using only age, sex, height, weight and 20 self‑reported functional items, AITIS achieved...
Gut Microbiota and Pediatric Eye Diseases: Current Insights, Mechanistic Underpinnings, and Future Outlook
A 2026 Frontiers in Nutrition review links early‑life gut microbiota dysbiosis to several common pediatric eye disorders, including allergic conjunctivitis, myopia, retinopathy of prematurity (ROP) and postoperative inflammation after congenital cataract surgery. The authors synthesize evidence that immune imbalance, microbial...
Association Between the Non-High-Density Lipoprotein Cholesterol to High-Density Lipoprotein Cholesterol Ratio and Carotid Plaque: A Retrospective Cohort Study
A retrospective cohort of 5,985 Chinese adults followed for an average of 2.2 years found that a higher non‑HDL‑C to HDL‑C ratio (NHHR) independently predicts incident carotid plaque. Participants in the top NHHR quartile experienced a 64% greater hazard of...
Gut Microbiota-Liver-Kidney Axis in Diabetic Kidney Disease: Mechanistic Insights Into Amino Acid Metabolism and Nutritional Intervention Strategies Targeting Natural Bioactive...
Diabetic kidney disease (DKD) is accelerating as diabetes prevalence climbs, now affecting up to 40% of diabetics and driving a surge in end‑stage renal disease. Recent research highlights a gut‑microbiota‑liver‑kidney axis that links dietary nutrients to kidney injury through metabolites...
Mechanisms by Which Complex Carbohydrates Influence Immune Imbalance in COPD via the Gut–Lung Axis: From Colonic Fermentation to Pulmonary Immune...
Recent research highlights how the structural characteristics of dietary complex carbohydrates steer colonic fermentation, shaping the production of short‑chain fatty acids (SCFAs) and tryptophan metabolites that travel to the lungs. Faster‑degrading, low‑polymerization carbs generate SCFAs mainly in the proximal colon,...
Prognostic Value of the Triglyceride-Glucose (TyG) Index for Renal Function Progression in Patients with CKD Stages 3–4
A multicenter retrospective cohort of 53,607 Chinese patients with chronic kidney disease (CKD) stages 3‑4 found the triglyceride‑glucose (TyG) index to be an independent predictor of renal function progression. Each 1‑unit increase in TyG was linked to a 10% higher hazard,...
Negative Impact of Reduced Exocrine Pancreatic Function on Sarcopenia Risk in the Asymptomatic General Population
Researchers analyzed data from 5,598 asymptomatic German adults to assess whether reduced exocrine pancreatic function, measured by fecal elastase ≤200 µg/g, is linked to sarcopenia. They found a 9.1% prevalence of exocrine insufficiency and a 4.1% prevalence of sarcopenia, with a...
Early Combined Parenteral and Enteral Nutrition Support for Patients over 80 Years Old with Non-Operative Intestinal Obstruction
A retrospective study of 191 patients over 80 with non‑operative intestinal obstruction compared early combined parenteral and enteral nutrition (ECPEN) to delayed combined nutrition (DCPEN). After 1:1 propensity score matching, 79 pairs showed that ECPEN led to shorter total parenteral...
BeOne Medicines Licenses Trispecific Antibody Targeting PD-1, CTLA-4 and VEGF
BeOne Medicines, the rebranded former BeiGene, announced a licensing and option agreement to acquire a trispecific antibody that simultaneously targets PD‑1, CTLA‑4, and VEGF. The experimental biologic originates from a Chinese biotech and is positioned for development in solid‑tumor indications....
The Reason Nanoscale Gaps Can Produce Terahertz Radiation
Researchers have demonstrated a nano‑plasma device that generates 2 W peak terahertz power at 0.4 THz using a 100‑500 nm air gap. The breakthrough relies on a secondary electron emission avalanche (SEEA) on the substrate, which creates an ultra‑dense electron sheet that seeds...
Sandwiching Ligands Finally Make Iron(I) Stable in Air
Researchers at Karlsruhe Institute of Technology have synthesized a new iron(I) complex where two durene ligands sandwich the metal, rendering it stable enough to handle in air. The purple‑crystalline reagent avoids the spontaneous ignition that plagues traditional iron(I) compounds and...
Boehringer, Zealand’s Obesity Drug ‘More Akin’ to Novo’s Wegovy in Phase 3
Boehringer Ingelheim and Zealand Pharma reported that their glucagon/GLP‑1 dual agonist survodutide achieved a 13.4% (39.2 lb) average weight loss after 76 weeks in the Phase 3 SYNCHRONIZE‑1 trial, meeting primary endpoints and reducing waist circumference. Analysts compared the outcome to Novo...
Why Stars Spin Down, or up, Before They Die
Researchers at Kyoto University used 3‑D magnetohydrodynamic simulations to explore how convection, rotation, and magnetic fields interact in massive stars nearing core collapse. The study shows that magnetic field geometry can both spin down and, unexpectedly, spin up stellar cores,...
AACR 2026: Combo Therapies by Moderna, Marengo Show Promise in Skin, Breast Cancer
Combination regimens dominated AACR 2026, with biotech firms showcasing new cocktail data across multiple tumor types. Marengo Therapeutics reported that its dual‑T‑cell agonist invikafusp alfa combined with Gilead’s ADC Trodelvy produced complete or partial responses in 40% of heavily pretreated...
A Shape No Engineer Would Dream up Makes Thermoelectric Generators 8 Times Better
Researchers at POSTECH and UNIST used topology optimization to create a thermoelectric generator with a computer‑designed geometry that outperforms conventional rectangular devices by more than eight times. The method evaluates heat flow, electrical resistance, contact losses and load conditions to...
Crafting Flavor in Hydroponically Grown Lettuce with CRISPR
Researchers used CRISPR/Cas9 to knock out the DFR gene in red‑leaf lettuce, producing a green‑pigmented line without compromising growth. The edited plants lost anthocyanin coloration, while some lines showed a rise in total flavonoids. Metabolite profiling confirmed a sharp drop...
Microplastics Found in Most Human Brains, Concentrated Near Tumors
Microplastics and nanoplastics have been detected in nearly all human brain samples, including healthy tissue, with higher concentrations observed near tumors, raising new questions about their potential impact on brain health. microplastics
Another One: Ariane 6 Flies with Four Boosters Once More
Europe’s Ariane 6 rocket is set for its seventh flight, VA268, on 30 April 2026, this time using four P120C solid boosters. The launch will deliver 32 Amazon Leo satellites to low‑Earth orbit, employing a 20‑metre fairing and a 114‑minute mission timeline. Four...
Milestone for Crispr: First-of-Its-Kind Gene Editing Treatment Successfully Passes Clinical Trial
Intellia Therapeutics announced that its CRISPR‑based, one‑time gene‑editing therapy Lonzo‑z cleared a Phase 3 trial for hereditary angioedema, cutting swelling attacks by 87%. The double‑blind, placebo‑controlled study treated 52 of 80 patients and left 62% attack‑free without ongoing medication. Results represent...
STAT+: Boehringer’s Obesity Drug Shows 16.6% Weight Loss; More Data Needed
Boehringer Ingelheim reported that its experimental obesity drug produced an average 16.6% weight loss in a mid‑stage trial, signaling strong efficacy against a disease affecting over 100 million Americans. The study involved roughly 300 participants over 68 weeks and showed improvements...
Scientists Catch Antimatter “Atom” Acting Like a Wave for the First Time
A team from Tokyo University of Science has, for the first time, observed matter‑wave diffraction in a beam of positronium, the electron‑positron bound atom. By generating a high‑energy (up to 3.3 keV), coherent positronium stream and directing it through a few‑layer...
Probiotic Candidate Shows Potential to Suppress UTIs
Researchers reported that the probiotic strain Limosilactobacillus reuteri 3613‑1, which produces the antimicrobial compound reuterin, can inhibit key urinary and vaginal pathogens. In a randomized, double‑blind, placebo‑controlled trial of 130 healthy women taking the probiotic daily for 24 weeks, the...
Fasting Mimetic May Improve Cardiometabolic Health Markers: RCT
A randomized, double‑blind, placebo‑controlled trial found that an eight‑week regimen of Mimio, a fasting‑mimetic supplement, significantly improved cholesterol fractions, oxidized LDL, and fasting glucose in older adults with elevated BMI and HbA1c. The formulation delivers nicotinamide, PEA, OEA and spermidine...
French Team Directly Images Cooper‑Pair “Dance” In Superconductor Mimic
Researchers at France’s CNRS, led by Tarik Yefsah, captured the first direct images of paired atoms moving in a coordinated pattern inside a Fermi‑gas superconductor analog. The observation, published in Physical Review Letters, reveals interactions missing from the 70‑year‑old BCS...
Daily Multivitamin Slows Biological Aging Up to Five Months, Study Finds
Researchers led by Howard Sesso published a peer‑reviewed trial showing that a daily Centrum Silver‑type multivitamin slowed two epigenetic aging clocks by 2.7–5.1 months over two years. The finding, based on 958 participants from the COSMOS study, marks the first...
NVIDIA Constructs Full Quantum Stack Without Building Qubits
Fifteen months ago, Jensen wiped $8B off the quantum sector in an afternoon by saying useful quantum computers were 20 years away. Two months later, NVIDIA opened a quantum research center. Eight months after that, they shipped NVQLink. Last week, the AI model...
Molecular Tumor Boards Cut Costs, Reduce Recommendation Discordance
Quantifying the Value of Molecular Tumor Board: Discordance Recommendation Rate & Drug Cost Avoidance [10/20/22] Walters @JimW9200 @antonyruggeri @mullane_michael Hunt, Wilson, Ramczyk, @mtmdphd @JCOPO_ASCO https://t.co/OORXChBGjx #PrecisionMedicine #hpeonc @Aurora_Cancer https://t.co/ZUQXq4npfh
PurIST Classifier Validated for Tailored Pancreatic Cancer Therapy
Real-World Validation of the Purity Independent Subtyping of Tumors Classifier for Informing Therapy Selection [PurIST @TempusAI] in Pancreatic Ductal Adenocarcinoma [Sep 4, 2025] @stephwen et al. @JCOPO_ASCO https://t.co/R24DErvaB4 #pancsm #PrecisionMedicine https://t.co/KNJHtWovqT
Biliary Cancer Subtypes Show Distinct Immune Signatures
Clinical, Genomic, and Transcriptomic Data Profiling of Biliary Tract Cancer Reveals Subtype-Specific Immune Signatures [Jun 8, 2022] @kabir_mody et al. @MarkYarchoan @JCOPO_ASCO https://t.co/IN6UsL5jvN #hpbcsm #PrecisionMedicine https://t.co/p3BzJ82oxA
BRAF Class II/III Mutations Represent Unmet Clinical Need
Real-world clinical genomic analysis of Pts w/ BRAF mutated cancers identifies BRAF class II & III as a population of unmet medical need [3/7/22] Severson etal #ESMO2240P @TempusAI https://t.co/s5PEBEczlv @Annals_Oncology DOI: https://t.co/c3wxWyUuX0 #PrecisionMedicine #caxtx
ASCO Endorses Somatic Genomic Testing for Advanced Cancers
Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: @ASCO Provisional Clinical Opinion [Feb 17, 2022] @CDebyaniPhD et al. @JCO_ASCO https://t.co/hfHUBS3Unx #PrecisionMedicine https://t.co/GwYOMRD1hh
BRAFV600E‑mutated Pediatric Gliofibroma Shows Fleeting Therapy Response
Rare Pediatric Invasive Gliofibroma Has BRAFV600E Mutation and Transiently Responds to Targeted Therapy Before Progressive Clonal Evolution [Mar 27, 2019] @KanevaMD et al. @JCOPO_ASCO https://t.co/oNbfrK7EZr #PrecisionMedicine #btsm https://t.co/V7k9vEiqKm
KRASG12C Mutations Linked to Distinct Immuno‑oncology Biomarkers
Landscape of KRASG12C, Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in KRAS-Mutated Cancers [Mar 23, 2022] @SalemGIOncDoc et al. @JCOPO_ASCO https://t.co/iehC82lyA4 #ImmunoOnc #PrecisionMedicine @TempusAI https://t.co/wZzfdnBoXU
Real‑World Data Uncovers Unique Profile of Metastatic ILC
Molecular Characterization of Patients with Metastatic Invasive Lobular Carcinoma: Using Real-World Data to Describe This Unique Clinical Entity [Sep 10, 2025] Davis et al. @CCR_AACR https://t.co/eY0etUfQhQ #bcsm #PrecisionMedicine #camoldx @TempusAI https://t.co/WBcB4uGito
Comprehensive Genomic Panel Broadens Community Oncology Treatment Options
Unique Features of a Comprehensive Genomic Profiling Panel: Expanding Treatment Options in a Value-Based Community Oncology Network [Mar 9, 2026] La Porte et al. @DrEzraCohen @JCOPO_ASCO https://t.co/tDi3kbxdvX #PrecisionMedicine #hemeonc @TempusAI https://t.co/6QKo7c3oH2
Roman Space Telescope Launch May Shift to August
At Senate Approps CJS hrg, Isaacman just said Roman Space Telescope may perhaps launch in August instead of September.
AI Reads Retinal Images to Screen Multiple Diseases
What superhuman vision can detect from the retinal photo, which human eyes cannot, is stunning. A new foundation AI model screening for diabetes hypertension, hyperlipidemia, gout, osteoporosis, and thyroid disease @NatureMedicine https://t.co/GhKvUqz4Vy https://t.co/iKcXCbLceu
NIH Could Fund Groundbreaking Research with $2 B Annually
What could the NIH do with an extra $2 billion dollars a year from publisher fees?
Literate Programming Ensures Reproducible Bioinformatics Analyses
1/15 If your bioinformatics analysis isn't reproducible, it hurts science. Literate programming fixes this. Here's how to do it right 🧵 https://t.co/f06AXPUbpW
Turing's Halting Theorem Shows Life Has No Shortcut
Arguably the most elegant result in science belongs to Alan Turing. His theorem says that there is no way to predict if a computation will ever stop just by looking at its code means that life can’t be compressed into a...
Anthocyanins Improve Cardiometabolic and Anti‑
Anthocyanin supplementation in adults at risk for dementia: a randomized controlled trial on its cardiometabolic and anti-inflammatory biomarker effects https://t.co/tHwVYQ3yvQ https://t.co/cxiRpkIj7W