Know What's Happening in Biohacking
Know What's Happening in Biohacking
Creatine emerges as brain‑fuel supplement that counters sleep loss and stress
Creatine monohydrate, long known for muscle growth, is gaining scientific backing as a brain‑fueling supplement. Recent studies show that daily doses of 10‑25 g raise brain creatine levels and mitigate cognitive deficits caused by sleep deprivation and stress, improving processing speed and working memory.
Researchers at Drexel University analyzed food logs from 112 overweight adults in a 12‑week weight‑loss program and found that participants who ate the same meals daily lost 5.9% of body weight, compared with 4.3% for those with varied diets. The findings suggest that dietary consistency may be a powerful lever for weight‑loss success.
Researchers tracking more than 11,000 older adults for a decade found that those who held a positive view of aging were significantly more likely to improve cognitive test scores and walking speed. The findings give concrete evidence that mindset matters...
A team from Kochi University of Technology identified a distinct surge in brain activity an hour after acute stress, overturning the conventional view that stress responses peak within minutes. The finding, published in PNAS, highlights a 60‑minute window where the...
GARM, operating as Longevity Advanced, announced the addition of the anti‑aging protein Klotho to its gene‑therapy portfolio at its Roatán clinic. The move broadens a suite that already includes Follistatin and VEGF, positioning the center as a hub for high‑end...
Australian psychologist Millie Hardie launched a self‑talk hack on March 8, 2026, arguing that purposeful internal dialogue can rewire neural pathways and lift mental‑health outcomes. The claim, shared via an Instagram video, taps into neuroplasticity research and is quickly gaining...
IIT Madras has inaugurated the Center for Advanced Research on Spirituality, Science and Society, backed by a ₹5 crore ($600,000) donation from alumnus Sant Rajinder Singh Ji Maharaj. The hub will unite scholars across medicine, humanities and architecture to examine how...
New Paper - Evidence suggests regeneration may be a natural and achievable biological process worth prioritizing over merely slowing aging—ideally beginning in midlife (around 40–60) to postpone decline, with the potential to reverse aging later in older individuals. Insights from...
The systematic review and multilevel meta‑analysis of 17 randomized controlled trials involving 293 healthy participants found that chronic β‑alanine supplementation does not improve repeated sprint ability (RSA). Pooled standardized mean differences for mean RSA performance, peak performance, and fatigue decrement...
New research shows that the low‑FODMAP diet’s effectiveness for irritable bowel syndrome (IBS) depends as much on gut‑brain interactions as on food restriction. In a six‑month study of 112 adults, researchers tracked symptom changes across the diet’s restriction, reintroduction and...
In this episode, host Molly Eastman talks with Dr. Matt Bernstein, a psychiatrist and CEO of Accord, about metabolic psychiatry and how diet—particularly ketogenic nutrition—affects mental health, anxiety, and sleep. Dr. Bernstein explains the science behind ketosis, its impact on...
This isn't about judgment. It's about physiology. If 3 or more of these describe you, your nervous system is trying to tell you something. Comment Sleep Fix and I'll send you my 7-day sleep Reset. Save this so you remember you're not...
Just 3 all-out sprints for 20 sec repeated 3x a week can result in the same VO2 max gains (+19%) as 45 min of steady cardio once a week. The difference: 20 min less time spent on training. Caveat: done on sedentary...
An international team led by Zhejiang University and USC researchers has released the first region‑by‑region genetic map of brain aging, while a separate study of 1,647 adults finds the MIND diet can delay brain aging by roughly 2.5 years. The...
Scientists at Baylor College of Medicine identified a brain pathway that enables metformin to lower blood sugar, a discovery that could expand the drug’s use beyond diabetes and fuel new longevity protocols among biohackers.
Cellular senescence has become a focal point for longevity medicine, prompting a surge of senolytic and senomorphic drug development. Pioneering studies showed that clearing senescent cells can extend healthspan, leading biotech firms like Rubedo, SENISCA, Deciduous Therapeutics, and Arda Therapeutics...
One large psilocybin dose beat nicotine patches by 6x odds for smoking cessation. 82 otherwise-healthy cigarette smokers, 42 received a single high-dose 30mg/70kg psilocybin session, and 40 initiated an 8- to 10-week course of nicotine patch treatment. At 6 months; participants were 6x...
There is strong evidence that similar hypertrophy can be achieved across a wide range of loading schemes (~5 to 30+ repetitions), provided sets are performed close to muscular failure. That said, some data suggest fiber type–specific differences, with heavier loads...
A NutraIngredients webinar highlighted how GLP‑1 agonists, wearables, and at‑home diagnostics are reshaping personalized health. Over 25‑30 million people are currently on GLP‑1 drugs, a figure expected to double by 2030, while roughly 100 million U.S. consumers now wear devices that generate...
Cyclists often overlook the diaphragm, yet it powers the breath that fuels every pedal stroke. Research and expert insight reveal that many riders habitually breathe shallowly, using chest muscles instead of the diaphragm, which limits oxygen intake and hampers performance....
A recent Belgian study published in the Journal of Physiology examined exogenous ketone supplementation around training. Researchers found that consuming ketones during exercise did not improve performance metrics. However, taking ketone esters after a workout appeared to accelerate metabolic recovery...
Jen Smiley introduces the "Wake Up Shot," a two‑minute, ten‑second morning drink that blends fresh ginger, lemon juice, turmeric with black pepper, and water. The recipe claims to improve digestion, lower inflammation, boost energy, and support immunity when taken first...
Gyms are evolving to integrate services that are looking beyond near-future fitness and into longer-term benefits. The concept of longevity has gained traction in recent years, and gyms are tapping into this trend. In this article, by analysing real-life trends and examples,...
A joint study by the American Psychological Association, Harvard Health Publishing and the National Institute on Aging released data showing an unprecedented stress surge among women aged 35‑54. The findings link chronic pressure to fatigue, anxiety, sleep problems and heightened...
As a medical school professor, I can tell you: the textbooks got this one wrong. We taught that once you have prostate cancer, exercise is nice but optional. New data says it may be the most powerful tool in your arsenal. 828...
“These findings challenge the assumption that lifespan extension necessarily compresses morbidity, highlighting the need to consider lifespan, healthspan, and CoM as endpoints when evaluating anti-aging interventions. We do not claim that life-extending interventions categorically fail to achieve CoM; rather, we demonstrate...
A recent Lithuanian Sports University study examined short‑term broccoli powder supplementation in 17 healthy men performing an incremental bike‑ergometer test. Participants consumed 10 g of broccoli powder (0.5 % mustard seed) for 14 days, which significantly increased urinary sulforaphane, confirming absorption. However,...
A Nestlé‑backed randomized trial gave healthy men 714 mg nicotinamide and 19 mg pyridoxine daily for nine days after intense eccentric exercise. The B‑vitamin combo boosted muscle stem cell numbers by 29% and accelerated differentiation markers—MyoD+ cells rose 67%, myogenin+ cells 34%,...
Researchers published in Brain Communications found that just 20 minutes of moderate‑intensity cardio can increase hippocampal ripple activity, a brain rhythm linked to memory consolidation. The study monitored 14 drug‑resistant epilepsy patients with implanted electrodes before and after cycling, observing...
The International Breathwork Foundation (IBF) announced the global rollout of World Breathing Day on April 11, 2026, under the theme “Pause, Breathe, Unite.” The initiative will combine in‑person gatherings, Zoom workshops and a social‑media challenge to promote conscious breathing as...
Eli Lilly announced top‑line results from the Phase III TRANSCEND‑T2D‑1 trial, showing its investigational triple‑hormone agonist retatrutide reduced HbA1c by up to 2 percentage points and produced an average 16.8 % weight loss over 40 weeks. The data position retatrutide as a potential...
The post recounts John Calhoun’s 1968 “Universe 25” mouse experiment, where abundant food, water and shelter failed to stop a colony’s collapse once social roles became saturated. Mice entered a “beautiful” phase, losing reproductive drive and social behavior, leading to extinction...
In this episode, Dr. Paola Sebastiani explains how the genetics of extreme longevity are far more complex than a single "longevity gene," highlighting the growing list of genetic variants—such as APOE, chromosome 9 loci, and inflammation‑related regions on chromosome 6—that...
Exercise, especially resistance training and high‑intensity interval work, has been shown to raise testosterone levels in men both acutely and over the long term. Declining hormone levels are linked to obesity, stress, and sedentary lifestyles, prompting a shift toward natural,...
A 19‑year Swedish cohort study of 20,811 adults aged 35‑64 found that mentally passive sedentary activities, such as TV watching, increase dementia risk, while mentally active sitting—reading or desk work—significantly lowers it. Substituting equal amounts of passive with active sedentary...
Chris Froome, the four‑time Tour de France winner, has been appointed chief innovation officer at sport‑technology company Vekta. The hire places a celebrated athlete at the helm of product strategy for AI‑driven training tools, underscoring a growing trend of athletes...
In a fresh interview, neuroscientist Julia Rodríguez Teba warned that mental noise fuels stress, decision‑making blocks and emotional overload. She launched the Brain Star Training system and her new book ‘Sin Ruido’ (‘Without Noise’) to make applied neuroscience tools available...
Benefits of Raw Honey: 🍯 Contains polyphenols, which help protect cells from damage and reduce inflammation. 🍯Studies show it can be as effective as some over-the-counter cough medications for reducing cough frequency and severity. 🍯 Its antibacterial properties make it effective for treating...
Apparently aging isn’t a disease because it’s “natural,” therefore it should be managed, not treated I disagree. Aging has causes, biomarkers, clear pathology, and is modifiable If something can be measured & treated, it should be considered a disease https://t.co/a2a2cNdobC
The conversation between Gabrielle Lyon and Dr. Tommy Wood reframes brain health as a dynamic process driven by stress management, cognitive demand, and social engagement rather than a static disease‑prevention checklist. Research shows that interpreting stress as a challenge, maintaining...
NAD⁺ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence https://t.co/au5YIC11Hw https://t.co/fMsAOSQF6f
24 hours of the 96 hour water fast are now complete. Been super easy so far. Shocked at how I’m not hungry. Good workout this morning still + a long walk after. LMNT, sparkling water, & black coffee have helped for...
The Working Scientist podcast with neuroscientist Joseph Jebelli reveals that true rest—naps, day‑dreaming, and time in nature—activates the brain’s default network, sharpening intelligence, creativity and decision‑making. He warns that overwork now kills roughly 750,000 people annually, a 20% increase since...
Can you improve sleep with nutrition? Learn how to optimise sleep for better recovery, adaptation and performance. https://t.co/SabVAOeY5n https://t.co/cASn0WvTvT
Prioritize training over protein count obsession (yes nutrition still matters but putting training first anchors the nutrition aspect). @foundmyfitness on the Huberman Lab podcast out now https://t.co/vQ9eIWHyF8
Gene therapy isn't just targeting diseases anymore—it's targeting aging itself. The hallmarks of aging are becoming editable code. Longevity Escape Velocity isn't a fantasy. It's an engineering problem. And we're solving it.
The fitness industry misunderstands post-workout CNS fatigue more than any other physiological concept. Learn how it actually works in this week's free Patreon article. https://t.co/L5B5n6Ltt0
I'd still rather measure the actual biomarkers, but the best epigenetic clocks (PhenoAge, GrimAge, DunedinPACE) are consistently associated with all-cause mortality risk Another study was just published showing this: https://t.co/RZntDTn02c
Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations 🐒"These results parallel recent findings from humans in demonstrating that chronic inflammation is not a natural consequence of aging but may rather be driven by environmental contexts that are mismatched to the evolutionary...
