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Small (Wiley)

Small (Wiley)

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International peer-reviewed journal from Wiley focusing on nano- and microscale science and technology, highlighting innovative research in nanoscience.

Recent Posts

Spatiotemporal Co‐Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi‐Modal In Vivo...
News•Feb 16, 2026

Spatiotemporal Co‐Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi‐Modal In Vivo...

Researchers introduced a microneedle patch (MN‑Mg) that simultaneously delivers hydrogen gas and magnesium ions directly into the injured spinal cord. The hydrogen component rapidly scavenges reactive oxygen species, cutting oxidative stress by roughly 55%, while the magnesium release sustains microglial polarization toward a reparative M2 phenotype and boosts axonal growth. In a rat model, this spatiotemporal dual‑engine approach lifted locomotor scores from 5.5 to 14.8 within eight weeks, demonstrating functional recovery beyond conventional treatments. The platform merges mechanical penetration, controlled chemistry, and immunomodulation into a single implantable device.

By Small (Wiley)
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration
News•Feb 16, 2026

Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration

Researchers have created piezoelectric nerve guidance conduits (NGCs) that incorporate zinc oxide nanoparticles and multidimensional oriented structures. The conduits are fabricated by merging digital light processing (DLP) 3D printing with directional freezing, producing channels and micropores that align regenerating axons....

By Small (Wiley)
A Facile Magnetically‐Confined Plasma Strategy for Distinct Phase Modulation of Iron Nitride Nano‐Frameworks
News•Feb 16, 2026

A Facile Magnetically‐Confined Plasma Strategy for Distinct Phase Modulation of Iron Nitride Nano‐Frameworks

Researchers have introduced a magnetically‑confined plasma technique that precisely modulates the crystal phase of iron nitride nano‑frameworks on iron substrates. By tuning the magnetic field strength, the process switches the nitride from orthorhombic Fe2N to trigonal Fe2N, while conventional plasma...

By Small (Wiley)
Large‐Scale Cooperative Sulfur Vacancy Dynamics in Two‐Dimensional Mos2 From Machine Learning Interatomic Potentials
News•Feb 16, 2026

Large‐Scale Cooperative Sulfur Vacancy Dynamics in Two‐Dimensional Mos2 From Machine Learning Interatomic Potentials

Researchers applied two machine‑learning interatomic potentials to monolayer MoS2, achieving nanosecond‑scale molecular dynamics that accurately capture sulfur vacancy migration. The study demonstrates cooperative vacancy transport, cluster incorporation, and the emergence of line defects spanning tens of nanometres. Results align closely...

By Small (Wiley)
Blue‐Light‐Excited Cyan‐Emitting Carbon‐Dot‐Ormosil Gel for Blue‐Overshoot Mitigation and Cyan‐Gap Bridging in WLEDs
News•Feb 16, 2026

Blue‐Light‐Excited Cyan‐Emitting Carbon‐Dot‐Ormosil Gel for Blue‐Overshoot Mitigation and Cyan‐Gap Bridging in WLEDs

Researchers have created a carbon‑dot (CD)‑Ormosil gel that absorbs strongly at 450 nm and emits cyan light at 485 nm and 520 nm. The gel can be integrated with existing yellow phosphors in white LEDs to suppress the problematic blue‑overshoot and fill the...

By Small (Wiley)
Polarization‐Dependent Elliptical and Rectangular Mie Voids
News•Feb 16, 2026

Polarization‐Dependent Elliptical and Rectangular Mie Voids

Researchers have introduced anisotropic low‑index voids—elliptical and rectangular—into high‑index materials to create polarization‑dependent Mie resonances. By varying void geometry, they achieve controlled spectral shifts and distinct optical modes for each polarization state. The effect is demonstrated through nanoscale color printing...

By Small (Wiley)
Mechanistic Insights Into Cathode Degradation During Startup‐Shutdown of PEM Water Electrolysis and Mitigation via Semi‐Embedded Pt/CeOx
News•Feb 16, 2026

Mechanistic Insights Into Cathode Degradation During Startup‐Shutdown of PEM Water Electrolysis and Mitigation via Semi‐Embedded Pt/CeOx

Researchers identified cathode degradation in PEM water electrolyzers during startup‑shutdown cycles, where cathode potential spikes to ~1.0 V causing carbon corrosion and Pt agglomeration. They demonstrated that commercial Pt/C suffers rapid performance loss under realistic cycling. A semi‑embedded Pt/CeOx catalyst was...

By Small (Wiley)
Defect‐Morphology Dual Strategy to Achieve Coral‐Like La1‐xNi0.5‐yFe0.5O3‐δ/NiO Bifunctional Catalysts for High‐Performance Li‐O2 Batteries
News•Feb 16, 2026

Defect‐Morphology Dual Strategy to Achieve Coral‐Like La1‐xNi0.5‐yFe0.5O3‐δ/NiO Bifunctional Catalysts for High‐Performance Li‐O2 Batteries

Researchers introduced a dual‑strategy design—La‑site deficiency and EDTA‑driven morphological control—to synthesize coral‑like La1‑xNi0.5‑yFe0.5O3‑δ/NiO composites for Li‑O2 batteries. The deficiency generates in‑situ NiO phases and tunes oxygen‑vacancy concentrations, while the chelating agent creates a three‑dimensional porous network that accelerates ion diffusion....

By Small (Wiley)
Natural Green Antioxidant Proanthocyanidin Enhances the UV/Oxidation Resistance of Perovskite Solar Cells Through Buried Interface Modification Strategy
News•Feb 15, 2026

Natural Green Antioxidant Proanthocyanidin Enhances the UV/Oxidation Resistance of Perovskite Solar Cells Through Buried Interface Modification Strategy

Researchers introduced natural grape‑seed proanthocyanidins (OPC) at the TiO₂/perovskite buried interface of perovskite solar cells, employing a combined antioxidant, passivation, and UV‑protection strategy. The hydrogen‑bond network created by OPC reduces defect states on the electron‑transport layer, suppresses carrier recombination, and...

By Small (Wiley)
Record‐Low Compressibility in [N(C2H5)3CH3]FeCl4 Expands Phase Engineering Horizons in Hybrid Molecular Ferroelectrics
News•Feb 9, 2026

Record‐Low Compressibility in [N(C2H5)3CH3]FeCl4 Expands Phase Engineering Horizons in Hybrid Molecular Ferroelectrics

Researchers report that the lead‑free hybrid ferroelectric [N(C2H5)3CH3]FeCl4 (EMAFC) exhibits a bulk modulus of 42 GPa, the lowest compressibility recorded for any molecular ferroelectric. The material remains structurally stable and mechano‑chromic up to 51.5 GPa, undergoing a reversible P63mc‑to‑P1 phase transition at...

By Small (Wiley)
A Perspective on Commercializing Perovskite Solar Cells: Unlocking Opportunities in Niche Applications
News•Feb 9, 2026

A Perspective on Commercializing Perovskite Solar Cells: Unlocking Opportunities in Niche Applications

Perovskite solar cells have reached certified efficiencies above 25 percent, rivaling silicon panels, but commercialization remains constrained by scaling, stability, and cost challenges. The article outlines strategies such as tandem architectures and targeting niche markets—like building‑integrated photovoltaics and aerospace—to leverage perovskite’s...

By Small (Wiley)
Incoherent‐Light‐Excitable Lanthanide Upconversion Enabled by Highly Hydrophilic and Photostable Dye Sensitization
News•Feb 9, 2026

Incoherent‐Light‐Excitable Lanthanide Upconversion Enabled by Highly Hydrophilic and Photostable Dye Sensitization

Researchers introduced a one‑step coating method that transforms dye‑sensitized lanthanide upconversion nanoparticles (dsUCNPs) from hydrophobic, photolabile probes into highly hydrophilic, photostable agents. By applying unsaturated fatty acid salts—particularly sodium linolenate—the particles gain superior water dispersibility and a photobleaching half‑life 87...

By Small (Wiley)
Spontaneously Formed Orientation Polarization Thin Films for Engineering Organic‐Organic Interfaces
News•Feb 9, 2026

Spontaneously Formed Orientation Polarization Thin Films for Engineering Organic‐Organic Interfaces

Researchers have demonstrated that vacuum‑deposited thin films of specially designed polar molecules can spontaneously develop orientation polarization (SOP) by tilting their permanent dipoles against the substrate. By incorporating multiple fluoroalkyl substituents, the molecules achieve extreme structural asymmetry, producing a record‑high...

By Small (Wiley)
Structure‐Property‐Application Correlations of Early Transition Metal Chalcogenides: A Dichalcogenide‐Centered Perspective
News•Feb 9, 2026

Structure‐Property‐Application Correlations of Early Transition Metal Chalcogenides: A Dichalcogenide‐Centered Perspective

Early transition metal (ETM) chalcogenides display a broad structural palette, from disulfides to polychalcogenides, enabling tunable electronic, catalytic, and memory functionalities. The review adopts a dichalcogenide‑centered lens to link crystal polymorphism with performance in 2‑D devices, phase‑change memory, and energy...

By Small (Wiley)
Hierarchically Structured Artificial SEI with Interlayer Electronic Coupling for High‐Performance Aqueous Zinc Batteries
News•Feb 9, 2026

Hierarchically Structured Artificial SEI with Interlayer Electronic Coupling for High‐Performance Aqueous Zinc Batteries

Researchers introduced a hierarchically structured artificial solid‑electrolyte interphase (SEI) called ZnO@MX‑DE for aqueous zinc‑ion batteries. The engineered petalosphere heterostructure creates interlayer electron coupling that directs Zn²⁺ transport while repelling SO₄²⁻, dramatically improving ionic conductivity and Zn²⁺ transference. Laboratory tests showed...

By Small (Wiley)
Colloidal Quasi‐2D Cs2AgBiBr6 Double Perovskite Nanosheets: Synthesis and Application as High‐Performance Photodetectors
News•Feb 9, 2026

Colloidal Quasi‐2D Cs2AgBiBr6 Double Perovskite Nanosheets: Synthesis and Application as High‐Performance Photodetectors

Researchers have developed a colloidal synthesis route for quasi‑2D Cs2AgBiBr6 double‑perovskite nanosheets, achieving lateral dimensions up to 1.4 µm and thickness of only a few nanometers. By fine‑tuning ligand chemistry and reaction temperature, they obtained high‑purity nanosheets suitable for optoelectronic integration....

By Small (Wiley)
Orbital‐Hybridization‐Driven N‐Fe‐Mo Interatomic Charge Bridges at Amorphous FeMoOx/Porous Carbon Nitride Interface Boosting Peroxymonosulfate Activation in Fenton‐like Reaction
News•Feb 9, 2026

Orbital‐Hybridization‐Driven N‐Fe‐Mo Interatomic Charge Bridges at Amorphous FeMoOx/Porous Carbon Nitride Interface Boosting Peroxymonosulfate Activation in Fenton‐like Reaction

Researchers engineered an amorphous FeMoOx/porous carbon nitride interface featuring N‑Fe‑Mo interatomic charge bridges via orbital hybridization. This design accelerates electron transfer to peroxymonosulfate, dramatically lowering the Fe(III)→Fe(II) reduction barrier and favoring singlet oxygen generation. In a continuous‑flow test, the catalyst...

By Small (Wiley)
Separation of Magnetic Microparticles With Different Molecular Surface Functionalizations by Close‐to‐Surface Traveling‐Wave Magnetophoresis
News•Feb 9, 2026

Separation of Magnetic Microparticles With Different Molecular Surface Functionalizations by Close‐to‐Surface Traveling‐Wave Magnetophoresis

Researchers demonstrated that magnetic microparticles (MPs) driven by traveling‑wave magnetophoresis exhibit velocity differences when transported close to a substrate. The velocity disparity arises from surface‑functionalization‑dependent drag forces, as distinct polymer coatings (COOH vs COOH/NH2) change the average particle‑wall separation. Experiments...

By Small (Wiley)
High‐Density Co and N Dual‐Doping in Self‐Supporting 3D Graphene Aerogel for Synergistically Enhanced Supercapacitor Performance
News•Feb 9, 2026

High‐Density Co and N Dual‐Doping in Self‐Supporting 3D Graphene Aerogel for Synergistically Enhanced Supercapacitor Performance

Researchers introduced a one‑step hydrothermal method to co‑dope cobalt and nitrogen into a three‑dimensional graphene aerogel, creating a self‑supporting Co‑NGA electrode. The dual‑doping and porous architecture deliver a record specific capacitance of 2092 F/g at 1 A/g, far surpassing undoped graphene aerogels....

By Small (Wiley)
Hybrid Cryomicroneedles Enhance DC Vaccine Efficacy and Function as Non‐Typical Artificial Tertiary Lymphoid Structures to Provide Neuroprotective Immunity in Spinal...
News•Feb 9, 2026

Hybrid Cryomicroneedles Enhance DC Vaccine Efficacy and Function as Non‐Typical Artificial Tertiary Lymphoid Structures to Provide Neuroprotective Immunity in Spinal...

Researchers have engineered hybrid cryomicroneedle patches (pG/DL@npDC‑cryoMNs) that embed a neuroprotective dendritic cell vaccine within a methacrylated decellularized lymph‑node matrix and porous GelMA hydrogel. The device rapidly releases viable npDCs, triggers a strong CD4⁺ T‑cell response, and forms a non‑typical...

By Small (Wiley)
Designing a Silicon/Iron Selenide Heterojunction as Liquid and All‐Solid‐State Lithium‐Ion Battery Anodes Displaying Excellent Performances
News•Feb 9, 2026

Designing a Silicon/Iron Selenide Heterojunction as Liquid and All‐Solid‐State Lithium‐Ion Battery Anodes Displaying Excellent Performances

Researchers have engineered a silicon‑iron selenide heterojunction anode (Si@FeSe@C) featuring a robust Fe–Se–Si interfacial bond and an external carbon coating. The material delivers 1,092.8 mAh g⁻¹ after 100 cycles at 0.2 A g⁻¹ and sustains Coulombic efficiencies above 99.6% for 500 cycles at 1.0 A g⁻¹....

By Small (Wiley)
Ionic Polyimine Nanocomposite Membranes with Bidirectionally Tunable Mechanics for Flexible Electronics
News•Feb 9, 2026

Ionic Polyimine Nanocomposite Membranes with Bidirectionally Tunable Mechanics for Flexible Electronics

Researchers have created ionic polyimine nanocomposite membranes reinforced with inorganic conductive nanofillers (iCONs) via in‑situ polymerization. By varying iCONs loading, the membranes’ mechanics can be tuned bidirectionally—from highly flexible (76 % elongation) to rigid (8.56 MPa tensile strength). A wearable sensor built...

By Small (Wiley)
Inverse High‐Entropy Design Enables Superior Energy Storage in Moderate and High Electric Fields
News•Feb 9, 2026

Inverse High‐Entropy Design Enables Superior Energy Storage in Moderate and High Electric Fields

Researchers introduced an inverse high‑entropy design by embedding ferroelectric BaTiO3 into the quasi‑linear ceramic Bi1/6Na1/6Sr1/6Ca1/6Li1/6La1/6TiO3 matrix. This approach creates a weakly polar tetragonal phase that boosts polarization while maintaining breakdown strength. The resulting composites achieve recoverable energy densities up to...

By Small (Wiley)
Atomically Dispersed Co Anchored Into Highly Nitrogen‐Doped One‐Dimensional Mesoporous Carbon with Large Pore Size for Ultra‐Stable Potassium‐Ion Storage
News•Feb 9, 2026

Atomically Dispersed Co Anchored Into Highly Nitrogen‐Doped One‐Dimensional Mesoporous Carbon with Large Pore Size for Ultra‐Stable Potassium‐Ion Storage

Researchers introduced a cobalt single‑atom‑doped, nitrogen‑rich mesoporous carbon anchored on carbon nanotubes (Co‑NMC@CNTs) using a tetraethyl orthosilicate‑mediated co‑assembly route. The composite exhibits a large 23.7 nm mesopore size, robust one‑dimensional structure, and 13.6 at% nitrogen doping, which together lower potassium‑ion diffusion barriers....

By Small (Wiley)
Exposure to Grilled Lamb‐Borne Carbon Quantum Dots Induces Intrahepatic Cholestasis by Activating the Intestinal Microbial‐Derived Lipopolysaccharide‐TLR4 Pathway
News•Feb 7, 2026

Exposure to Grilled Lamb‐Borne Carbon Quantum Dots Induces Intrahepatic Cholestasis by Activating the Intestinal Microbial‐Derived Lipopolysaccharide‐TLR4 Pathway

Researchers discovered that carbon quantum dots (CQDs) released from grilled lamb accumulate in mice after nine weeks of oral exposure at 25 mg kg⁻¹, damaging liver and intestinal barriers. The CQDs elevate gut‑derived lipopolysaccharide, triggering the intestinal LPS‑TLR4‑MyD88 signaling cascade and hepatic...

By Small (Wiley)
Advanced Photoporation: Micro‐Nanostructures for Size‐Specific Highly Efficient Biomolecular Delivery
News•Feb 7, 2026

Advanced Photoporation: Micro‐Nanostructures for Size‐Specific Highly Efficient Biomolecular Delivery

Photoporation is emerging as a versatile, non‑viral platform for intracellular delivery, and a new review proposes a size‑centric framework that categorises strategies by cargo dimensions rather than by laser or material type. The authors analyse how micro‑ and nanostructured substrates...

By Small (Wiley)
Biocompatible Glue‐Enabled Drug Localization and Mechanical Reinforcement of Lyophilized Microneedle Systems
News•Feb 7, 2026

Biocompatible Glue‐Enabled Drug Localization and Mechanical Reinforcement of Lyophilized Microneedle Systems

The Lyophilized Microneedle System with Biocompatible Glue (LMS‑BG) integrates a porous, drug‑loaded microneedle tip with a biodegradable ethanol‑based glue to create a mechanically robust, ultra‑fast dissolving transdermal platform. In tests using lidocaine, the system dissolved 11‑times faster than conventional dissolving...

By Small (Wiley)
Cu–O–In Bridge Engineering in Cu2O/In2O3 Nanowires for Efficient CO2‐to‐CO Electroreduction
News•Feb 7, 2026

Cu–O–In Bridge Engineering in Cu2O/In2O3 Nanowires for Efficient CO2‐to‐CO Electroreduction

Researchers have engineered a Cu2O/In2O3 heterointerface within three‑dimensional copper foam nanowires, creating Cu–O–In bridges that precisely tune the d‑band centers of Cu and In sites. This electronic modulation boosts CO2‑to‑CO electroreduction, achieving over 90% Faradaic efficiency across a wide potential...

By Small (Wiley)
Microstructure‐Interface Modulation Boosts Sodium Storage Capacity and Stability of Hard Carbon
News•Feb 7, 2026

Microstructure‐Interface Modulation Boosts Sodium Storage Capacity and Stability of Hard Carbon

The researchers applied a synergistic microstructure‑interface modulation to resin‑derived hard carbon, introducing carbonyl groups for reversible Na⁺ adsorption and using carboxyl/phenolic hydroxyl groups to anchor Zn²⁺ ions that template a hierarchical pore network. Expanded interlayer spacing further speeds Na⁺ intercalation,...

By Small (Wiley)
Bioinspired and Engineered Ion‐Selective Membranes Toward High‐Flux and High‐Selectivity Energy Devices
News•Feb 7, 2026

Bioinspired and Engineered Ion‐Selective Membranes Toward High‐Flux and High‐Selectivity Energy Devices

The review examines recent advances in ion‑selective membranes that aim to break the longstanding permeability‑selectivity trade‑off. By drawing inspiration from biological ion channels, researchers are engineering nanofluidic architectures, hybrid polymer‑nanomaterial composites, and AI‑assisted design tools to boost both ion flux...

By Small (Wiley)
Optimizing HostGuest Interaction Sites in Metal‐Organic Frameworks for Benchmark One‐Step Ethylene Purification
News•Feb 7, 2026

Optimizing HostGuest Interaction Sites in Metal‐Organic Frameworks for Benchmark One‐Step Ethylene Purification

Researchers introduced three conformational isomeric Fe3‑based metal‑organic frameworks (SNNU‑705‑α/β/γ) that strategically combine open metal sites, aromatic rings, and amino Lewis basic sites to preferentially adsorb acetylene and ethane while weakly binding ethylene. This host‑guest interaction design enables a benchmark one‑step...

By Small (Wiley)
Synthesis of Zirconium Boron‐Oxo Clusters With Tunable Third‐Order Nonlinear Optical Response
News•Feb 7, 2026

Synthesis of Zirconium Boron‐Oxo Clusters With Tunable Third‐Order Nonlinear Optical Response

Researchers have developed a modular synthesis route for zirconium boron‑oxo clusters (Zr‑BOCs) using in‑situ condensation of boron sources with dioxime ligands under pyrazole‑thermal conditions. The resulting planar Zr₂B₈O₁₀ cores feature d‑p‑π delocalization, and systematic ligand exchange with aromatic acids tunes...

By Small (Wiley)
Self‐Lubricating Nanofiber/Hollow Microsphere All‐Ceramic Architecture for Robust Flexible Thermal Insulation
News•Feb 7, 2026

Self‐Lubricating Nanofiber/Hollow Microsphere All‐Ceramic Architecture for Robust Flexible Thermal Insulation

Researchers have created an all‑inorganic SiO2 composite membrane by electrospinning nanofibers embedded with hollow silica microspheres. The resulting self‑lubricating 3D architecture delivers an ultralow thermal conductivity of 31.39 mW m⁻¹ K⁻¹ while maintaining exceptional flexibility, surviving over 100 000 bending cycles at 99 % strain....

By Small (Wiley)
Dynamically Reprograms Mitochondrial Respiration to Augment Cuproptosis in Cancer Therapy
News•Feb 7, 2026

Dynamically Reprograms Mitochondrial Respiration to Augment Cuproptosis in Cancer Therapy

Researchers engineered a copper‑coordinated polymer that transports lactate oxidase into cancer cells, converting intracellular lactate to pyruvate. This metabolic shift elevates mitochondrial respiration, sensitizing tumors to copper‑driven cuproptosis. Simultaneously, copper triggers DLAT oligomerization and a Fenton‑like reaction, inducing ferroptosis. In...

By Small (Wiley)
Biomimetic, Hierarchical‐Porous Composite Aerogel Fiber with Spectral Selectivity and Water Microchannels for Synergistic Radiative‐Evaporative Passive Cooling Textile
News•Feb 7, 2026

Biomimetic, Hierarchical‐Porous Composite Aerogel Fiber with Spectral Selectivity and Water Microchannels for Synergistic Radiative‐Evaporative Passive Cooling Textile

Researchers have created structure‑engineered aerogel fibers (SAFs) that replicate desert animal hair, using a double‑diffusion wet‑spinning process and hollow glass microspheres. The fibers exhibit 96.1% emissivity in the atmospheric window and 92.3% solar reflectivity, while their 93.9% internal porosity enables...

By Small (Wiley)
A Metal‐Free Phthalocyanine Additive for Defect Passivation and Processing Tolerance in High‐Efficiency Perovskite Solar Cells
News•Feb 7, 2026

A Metal‐Free Phthalocyanine Additive for Defect Passivation and Processing Tolerance in High‐Efficiency Perovskite Solar Cells

Researchers have introduced CG-0, a fully substituted, metal‑free phthalocyanine, as a highly soluble additive for wide‑bandgap perovskite solar cells. The additive simultaneously promotes defect passivation, controlled crystallization, and remarkable processing tolerance, allowing ultra‑high doping levels up to 1.75 mM. Devices incorporating...

By Small (Wiley)
Asymmetric Metal Oxide Electrodes for High‐Efficiency Evaporation‐Induced Energy Harvesting
News•Feb 7, 2026

Asymmetric Metal Oxide Electrodes for High‐Efficiency Evaporation‐Induced Energy Harvesting

Researchers have built an evaporation‑driven energy generator using a montmorillonite clay membrane and surface‑modified graphitic carbon electrodes coated with TiO₂ and Co₃O₄ nanowires. Replacing traditional copper contacts with these metal‑oxide electrodes boosted power output by roughly 8,000 times. The device...

By Small (Wiley)
NBD Integrated and Vitamin B6‐Driven Charge‐Reversible Peptide‐Based Nanocarriers for Targeted Therapeutic Delivery
News•Feb 7, 2026

NBD Integrated and Vitamin B6‐Driven Charge‐Reversible Peptide‐Based Nanocarriers for Targeted Therapeutic Delivery

Researchers have engineered a phenylalanine‑tryptophan dipeptide nanocarrier functionalized with the fluorescent probe NBD and a vitamin B6‑derived pH‑responsive unit. The self‑assembled nanospheres load doxorubicin with high efficiency and undergo charge reversal at mildly acidic pH, triggering rapid drug release and nuclear...

By Small (Wiley)
Dual Therapeutic Effects of Ultra‐Small Platinum‐Selenium Nanoparticles on Oxalate‐Induced Acute Kidney Injury
News•Feb 7, 2026

Dual Therapeutic Effects of Ultra‐Small Platinum‐Selenium Nanoparticles on Oxalate‐Induced Acute Kidney Injury

Researchers synthesized ultra‑small platinum‑selenium (Pt‑Se) nanoparticles that effectively halt calcium oxalate (CaOx) crystal nucleation and growth, reducing crystal‑cell interactions and oxidative damage. In vitro assays demonstrated strong inhibition of CaOx crystallization, while a hyperoxaluria mouse model showed markedly lower renal...

By Small (Wiley)
Fluorescently Labeled Gradient Hydrogels Reveal Matrix‐Dependent Cell Responses to Substrate Stiffness
News•Feb 7, 2026

Fluorescently Labeled Gradient Hydrogels Reveal Matrix‐Dependent Cell Responses to Substrate Stiffness

Researchers introduced a thermophoresis-based method to fabricate fluorescently labeled stiffness gradient hydrogels, enabling contactless stiffness mapping via standard microscopy. The technique leverages fluorescein isothiocyanate labeling, where fluorescence intensity reflects polymer concentration and thus stiffness. Experiments with gelatin methacryloyl (GelMA) and...

By Small (Wiley)
Synthesis of Atomically Dispersed Nickel Confined in Hierarchical MFI Zeolite
News•Feb 7, 2026

Synthesis of Atomically Dispersed Nickel Confined in Hierarchical MFI Zeolite

Researchers have developed a ligand‑protected in situ synthesis that embeds atomically dispersed nickel within hierarchical MFI zeolite. The tri‑functional template, combining quaternary ammonium heads and metal‑coordinated porphyrins, directs mesoporous architecture while suppressing nickel aggregation. The resulting catalyst displays uniformly distributed...

By Small (Wiley)
The Chemistry From Tin Iodide Molecular Inks to FASnI3 Nanocrystals
News•Feb 6, 2026

The Chemistry From Tin Iodide Molecular Inks to FASnI3 Nanocrystals

Researchers mapped how tin iodide (SnI2) complexes with two common Lewis bases—oleylamine and trioctylphosphine—affect the formation of tin halide perovskite nanostructures. In situ 119Sn NMR, UV‑Vis spectroscopy, and DFT calculations show that amine ligands bind more strongly than phosphines, and...

By Small (Wiley)
Structural Superlubricity and Triboelectric Nanogenerators in MEMS: Opportunities, Challenges, and Future Directions
News•Feb 6, 2026

Structural Superlubricity and Triboelectric Nanogenerators in MEMS: Opportunities, Challenges, and Future Directions

The review spotlights structural superlubricity (SSL) and triboelectric nanogenerators (TENGs) as dual solutions to the chronic friction, wear, and power constraints of microelectromechanical systems (MEMS). It details the underlying mechanisms, material choices, and fabrication routes that enable near‑zero friction interfaces...

By Small (Wiley)
Sp‐Hybridized Carbon Modulates the Spin States of Ir Nanozyme for Efficient Oxygen Activation
News•Feb 6, 2026

Sp‐Hybridized Carbon Modulates the Spin States of Ir Nanozyme for Efficient Oxygen Activation

Researchers engineered an Ir/GDY/CNT nanozyme where sp‑hybridized carbon (sp‑C) modulates iridium’s spin state from low‑spin to high‑spin. This creates a unique sp‑C‑O‑O‑Ir dual active site that accelerates oxygen activation, delivering a 6.2‑fold boost in oxidase‑like activity versus pristine Ir nanoparticles...

By Small (Wiley)
Bioinspired Multifunctional Carbon Platforms Decorated with MoS2/Au Nanohybrids for Integrated Antibacterial and Electromagnetic Shielding Performance
News•Feb 6, 2026

Bioinspired Multifunctional Carbon Platforms Decorated with MoS2/Au Nanohybrids for Integrated Antibacterial and Electromagnetic Shielding Performance

The study introduces a biomimetic carbon cloth platform patterned after Oxalis leaves and functionalized with MoS2 nanosheets and gold nanoparticles. This hierarchical structure delivers three synergistic effects: mechano‑bactericidal surface killing, photocatalytic sterilization under light, and reflection‑dominant electromagnetic interference (EMI) shielding...

By Small (Wiley)
Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders
News•Feb 6, 2026

Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders

Researchers demonstrated that polystyrene nanoplastics (PS‑NPs) are internalized by gonadotropin‑releasing hormone (GnRH) neurons and disrupt their function. In hormone‑secreting GT1‑7 cells, PS‑NP exposure lowered GnRH release, while in migrating GN11 progenitors it impaired cell movement. Transcriptomic profiling identified altered expression...

By Small (Wiley)
Graphene Oxide Nanosheets as Direct Photosensitizers for Photodynamic Therapy in a Size‐Dependent Manner
News•Feb 6, 2026

Graphene Oxide Nanosheets as Direct Photosensitizers for Photodynamic Therapy in a Size‐Dependent Manner

Researchers discovered that graphene oxide (GO) nanosheets act as direct photosensitizers for photodynamic therapy (PDT) when their lateral size exceeds ~3.5 µm. Under near‑infrared (NIR) irradiation, large GO generates abundant reactive oxygen species (ROS), driving oral squamous cell carcinoma viability down...

By Small (Wiley)
Short‐Range‐Engineered Nd‐Doped IrOx Enables Oxide Path Mechanism for High‐Performance PEM Water Electrolysis
News•Feb 6, 2026

Short‐Range‐Engineered Nd‐Doped IrOx Enables Oxide Path Mechanism for High‐Performance PEM Water Electrolysis

Researchers have developed a neodymium‑doped amorphous IrOx catalyst that restructures the short‑range lattice to enable the oxide‑path mechanism for oxygen evolution. This design lowers the OER overpotential to 254 mV at 10 mA cm⁻² and sustains activity for 520 hours. In PEM water electrolyzers,...

By Small (Wiley)
Unveiling a Tetrahedrally Coordinated Cobalt‐Nucleotide Hydrogel as an Efficient Bifunctional Electrocatalyst for Alkaline Water Electrolysis
News•Feb 6, 2026

Unveiling a Tetrahedrally Coordinated Cobalt‐Nucleotide Hydrogel as an Efficient Bifunctional Electrocatalyst for Alkaline Water Electrolysis

Researchers have created a cobalt‑adenosine monophosphate (CAH) hydrogel that functions as a bifunctional electrocatalyst for alkaline water electrolysis. The hydrogel delivers a cell voltage of 1.56 V at 10 mA cm⁻², outperforming the conventional IrO₂||Pt/C benchmark. Its performance stems from phosphate coordination, a...

By Small (Wiley)

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