Know What's Happening in Science
Know What's Happening in Science
High‑altitude hypoxia curbs blood‑sugar spikes in mice
A mouse study found that low‑oxygen (hypoxic) conditions cause red blood cells to absorb far more glucose and convert it into a molecule that eases oxygen release, acting as a glucose sink. Mice exposed to 8% oxygen showed markedly smaller blood‑sugar spikes after glucose injections, and the effect persisted after they returned to normal air.
Researchers from USC’s CLEAN Waters project report that, a year after the 2025 Palisades and Eaton fires, lead and other heavy metals in Los Angeles coastal waters and sand remain well below EPA and California safety limits. Initial spikes recorded by Heal the Bay have subsided, with peak seawater lead at just over 1 µg/L and sand lead never exceeding 14 ppm. The study confirms no observable harm to marine life or human health, though it calls for ongoing monitoring due to future rain‑driven runoff. State agencies echo the conclusion, noting localized metal elevations but no lasting threat.
Shionogi announced the first patient enrollment in its global Phase II Esprit trial, evaluating the oral substrate‑reduction therapy S‑606001 in adults with late‑onset Pompe disease. The 52‑week, double‑blind, placebo‑controlled study will run across the EU, the UK and the United States,...
Researchers have identified a new spider species in Ecuador’s Amazon that mimics the appearance of the parasitic fungus Gibellula, a relative of the cordyceps made famous by “The Last of Us.” The spider, belonging to the rarely seen genus Taczanowskia,...
Researchers at Technion’s Levenberg Laboratory have created a first‑of‑its‑kind three‑dimensional implant that merges muscle, fat, a hierarchical blood vessel network and, uniquely, a lymphatic system. The construct is printed with a custom extracellular‑matrix bio‑ink and matured in a flow‑controlled bioreactor....
Psychedelic research has surged, but recent psilocybin trials reveal modest benefits that fail to outpace placebo. A German study with 144 treatment‑resistant depression patients found no statistically significant advantage for high‑dose psilocybin. An open‑label review of 24 trials concluded psychedelics...
An interesting episode to add to your podcast list 👇 (There are many unintuitive parts when trying to understand quantum mechanics. This excellent episode explains one of them.)
Donut Labs announced a solid‑state battery that it says reaches 400 Wh/kg, a level far above the 250‑300 Wh/kg typical of today’s lithium‑ion cells. The company also touts thermal stability and fast‑charging, but it has not released voltage profiles or third‑party test...
An estimated 7‑ton meteoroid exploded over Ohio on March 17, producing a bright fireball and a sonic boom heard across the Midwest. The rock, roughly 6 feet in diameter, fragmented on impact, scattering black, fusion‑crusted pieces that residents and professional meteorite...
The European Space Agency announced it will purchase a dedicated SpaceX Crew Dragon flight to the International Space Station, creating the ESA Provided Institutional Crew (EPIC) mission. The EPIC flight is planned as a medium‑duration stay of roughly one month,...
Researchers have created a volatile memristor using the natural superlattice 2D material BiTiS3, which exploits interlayer coupling and sulfur‑vacancy‑induced lattice distortions to lower ion migration barriers. The device switches at low voltage within nanoseconds, as visualized by in‑situ conductive atomic...
The study introduces a bioinspired multifunctional flexible sensor (BMF) that mimics ant, spider, mosquito and lotus leaf structures. Built from MXene‑coated melamine foam and CNT/PVDF nanofiber membrane, it delivers ultra‑high pressure sensitivity of 986.51 kPa⁻¹ across 0–200 kPa and temperature sensitivity of...
Researchers introduced a succinonitrile (SN) coating on Li₅FeO₄ (LFO) particles, creating an air‑stable prelithiation additive (LFO@SN). The SN layer suppresses surface alkalization, preserving a high initial charge capacity of 623.8 mAh g⁻¹ after one hour of ambient exposure. In electrolyte, the coating...
The review surveys porous‑framework‑based triplet‑triplet annihilation upconversion (TTA‑UC) materials, emphasizing metal‑organic frameworks (MOFs) and porous aromatic frameworks (PAFs). It explains how these scaffolds improve oxygen resistance and enable solid‑state upconversion. The article details structure‑performance relationships, recent efficiency breakthroughs, and applications...
Ask Ethan: Does nature need to obey laws at all? One of the most profound facts about the Universe is that it obeys the same laws in all places and at all times. But why are there laws that govern it...
On March 20, 2026, the Moon will pass five degrees north of Venus, an alignment that coincides with the vernal equinox. While the conjunction occurs at 9 A.M. EDT, the two bodies become visible together in the evening sky, with Venus shining at...
#compchem #machinelearning #quantumcomputing New preprint: "The Convergence Frontier: Integrating Machine Learning and High Performance Quantum Computing for Next-Generation Drug Discovery". @qubit_pharma https://t.co/4D23DV0uAk
The John Bell Institute announces its 2026 Summer School on Space and Time, scheduled for August 17‑28 at the MEDLIS campus in Split, Croatia. It targets advanced master’s students, PhD candidates, and early‑career researchers, offering lectures, tutorials, and interactive discussions on...
Researchers Yuan Qiao and Ali Reza Kamali introduced a green, scalable polyimide binder modified with terephthalic acid for silicon anodes in lithium‑ion batteries. The binder reinforces electrode integrity, accelerates lithium‑ion kinetics, and boosts both capacity and long‑term cycling stability. Full‑cell...
Researchers used machine‑learning potentials and density‑functional theory to evaluate six dopants—Mg2+, Al3+, Ti4+, Zr4+, Nb5+ and Mo6+—in the P2‑type, cobalt‑free Na0.67Ni0.33Mn0.67O2 (NNMO) cathode. The study shows that high‑valence dopants (Zr, Nb, Mo) mainly reinforce bulk structural stability while preserving energy...
Researchers from the University of East Anglia and NHS Norfolk and Suffolk examined 5,057 social‑media posts and found high rates of misinformation about ADHD and autism, especially on TikTok. The study reported 52% of ADHD‑related TikTok videos and 41% of...
Not all impactful science is obvious at the start. Some begins as risky, collaborative experiments. This is one of those stories 👇 https://t.co/y3uhAYmXgB #INPST https://t.co/7Hruocwxb2
![[Comment] Physiologically Guided CABG in Valve Surgery](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/3fd1de683d722a591ac21ac5870e845d.webp)
Fractional flow reserve (FFR) provides a more precise physiological assessment of coronary lesions than angiography alone, and its wire‑based use has improved PCI outcomes. Angiography‑derived FFR extends this functional insight without pressure wires, showing strong correlation with invasive measurements. In...
![[Comment] Should We Keep Pushing a High Fluid Intake in Kidney Stones?](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/71728300caabf9cdd7e72489bb93c7ec.webp)
High fluid intake remains the cornerstone for preventing kidney stones, yet patient adherence is consistently low. Systematic reviews and a recent 2026 randomized trial confirm that adequate hydration reduces stone recurrence, but practical, behavioral, and environmental barriers limit real‑world effectiveness....
![[Editorial] Making Treatment for Obesity More Equitable](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/9ad50868737552068254155c5d608c4d.webp)
2026 could be a watershed year for obesity treatment as GLP‑1 receptor agonists cement their role after a decade of clinical success. The global market for weight‑loss drugs is forecast to hit US$150 billion by 2035, reflecting soaring demand. More than...
Single-cell aging clocks: A precision tool for dissecting and targeting the aging process https://t.co/5e47qWtZwH https://t.co/ImfBb45luO
A two‑year analysis of 656 overweight adults aged 55‑75 in the PREDIMED‑Plus trial found that participants who regularly consumed virgin olive oil exhibited better preservation of cognitive function and greater gut‑microbiome diversity than those who used refined olive oil. The...
A two‑year pilot trial published in JAMA Neurology found that low‑dose oral lithium (150‑300 mg daily) slowed verbal memory decline in older adults with mild cognitive impairment. The neuroprotective benefit was most pronounced in participants who tested positive for amyloid‑beta, a...
The National Institutes of Health announced a $150 million investment in the new Complement‑ARIE program to develop and standardize human‑focused research tools, known as new approach methodologies (NAMs). The initiative will fund technology development centers, a data hub, and a validation...
It was just 7 years ago… Glad to see the spread across the country & globe. #Nanofertilizer https://t.co/owi5grwnCS
A consortium of astronomers has announced the identification of 45 Earth‑like exoplanets that reside within the habitable zones of their host stars. The planets were selected from data gathered by space‑based missions such as Kepler, TESS, and ground‑based surveys, focusing...
Researchers from Denmark and collaborators reported that the hormone GDF15, known for causing nausea in early pregnancy, appears to rise in response to chronic alcohol consumption and may act as a feedback signal limiting intake. Small human studies at Oktoberfest...
Researchers from UCLA, Stanford, Utah, and Columbia have engineered T cell receptors to strengthen catch‑bond interactions with prostate cancer antigens, improving cytotoxic function. By altering just one or two amino acids in the TCR, the modified cells exhibit longer bond...
🧪⚛️ Quick thoughts on my last morning at the 2026 APS Global Summit and some wrap-up. https://t.co/LEhMpyK5fp
If you've had a kidney stone, you've been advised that the most important thing to prevent another bout is to increase hydration. Now a randomized trial of hydration in over 1600 participants showed no benefit, despite evidence of increase...
The authors of the Nature paper on the PP1‑PP2A phosphatase relay have issued a correction after a reader spotted a duplicated anti‑HA blot in Extended Data Fig. 7c. The duplicated image, originally a copy of panel e, has been replaced with the...
Physicists are nearing the first functional nuclear clock, which would keep time by measuring energy transitions in the nucleus of thorium‑229. A 2024 experiment finally pinpointed the elusive nuclear transition, unlocking the key to the device. Researchers worldwide are now...
Scientists at University College London have engineered bio‑grown oesophageal segments using patient‑derived stem cells and implanted them into minipigs, restoring normal swallowing. The grafts were seeded onto decellularized scaffolds, covered with a biodegradable mesh, and integrated functional muscle, nerves, and...
Ando Rabearisoa left a French PhD in 2009 to launch locally managed marine areas (LMMAs) across Madagascar, expanding them from 33 to 177 sites by 2019. The pilot LMMA recorded a 189% increase in fish biomass over six years, and...
New research presented at the American Heart Association’s EPI|Lifestyle Scientific Sessions 2026 shows that waist‑circumference and other measures of central obesity are stronger predictors of heart failure than body‑mass index, even among individuals with normal BMI. In a cohort of...
China’s biotech sector is experiencing a rapid surge, now hosting more CAR‑T cell trials than the United States. The growth is driven by a dual‑track regulatory framework that enables fast‑track, investigator‑initiated trials with minimal red tape. U.S. experts warn that...
Researchers at the Institute of Physical Chemistry (IPC PAS) and the University of Warsaw have created a magnetic‑field‑driven system that arranges endothelial‑cell‑coated microparticles into predefined lattices, prompting the growth of microvascular networks with precise architecture. By using super‑paramagnetic beads and micromagnets,...
Geroscience is for healthy life extension. We should stop pretending that lifespan and healthspan compete.👨⚕️
GTC 2026 was mind blowing and we’re covering the biggest takeaways on today’s Moonshots recording. Stay tuned https://t.co/whC6w6uYH3
Senator Sheldon Whitehouse announced a Senate Environment Committee probe into the Permian Basin after MethaneSAT satellite data revealed methane emissions four times higher than EPA estimates. The inquiry targets eight major oil and gas producers, demanding details on monitoring practices...
UCLA researchers have introduced a contact‑induced charge‑transfer doping technique that uses silver‑oxide nanoclusters to dramatically thin the metal‑perovskite interface from roughly 250 nm to under 25 nm, enabling quantum‑mechanical tunneling of electrons. Published in Nature Materials, the method replaces traditional bulk doping,...
Polish researchers have created a sub‑wavelength grating from molybdenum diselenide (MoSe₂) that confines infrared light within a 40‑nanometer‑thick layer. The high refractive index of MoSe₂ (≈4.5×) allows the grating to act as a perfect mirror despite its extreme thinness, a...
UCLA researchers published in Nature Neuroscience that the dorsomedial prefrontal cortex not only guides an individual mouse’s choices but continuously simulates the behavior of its peers during cold stress. Mice form huddles using four distinct social moves, and when the...
Research presented by Bourgault agronomist Curtis De Gooijer shows that placing nitrogen in the side band can cut canola emergence by up to 17% without a consistent impact on yield. Over nine years, side‑band and mid‑row nitrogen placements produced statistically...
Global surface air temperature anomalies have reached lowest value in several years, as weak La Nina conditions (following 23/24 El Nino) begin to dissipate. It will be interesting to see what happens if the forecast El Nino takes hold later this...
But one set of trials (TAD) were open label and other set of trials (psychedelic) included impt elements of experimental control, procedures like randomization and blinding. Does functional unblinding mid-session justify treating these trials as procedurally equivalent? No.
