
Artemis II crew prepares for historic lunar flyby
NASA’s Artemis II astronauts have passed the mission’s halfway point and are gearing up for a five‑hour lunar flyby on April 6, during which they will photograph the Moon’s far side. Orion has completed the trans‑lunar injection burn, placing the crew on a free‑return trajectory for the flyby.

Researchers have identified that a surface‑defensive molecule on cancer cells not only sends a “don’t‑eat‑me” signal but also conceals an “eat‑me” cue that would normally trigger immune clearance. A newly engineered antibody can disrupt this masking interaction, making tumors visible to immune patrol cells without fully blocking the molecule. The approach synergizes with existing checkpoint inhibitors and may avoid the anemia side effects seen with broad CD47 blockade. This discovery opens a fresh avenue for immunotherapy against cancers that resist current treatments.

The asteroids we should actually be worried about, the city killers… #space #asteroid #nasa #science #astrokobi
NASA's Artemis II mission, slated for early April, will send four astronauts on a ten‑day lunar flyby, becoming the first humans to view the Moon’s far side since Apollo. The crew will operate within 6,400‑9,000 km of the surface, capturing wide‑angle imagery,...

Artificial intelligence is moving from data analysis to hypothesis generation, fundamentally altering the scientific method. Recent work such as DeepMind’s GNoME system has generated millions of candidate materials, while neural networks have rediscovered physical laws without prior equations. These advances...

Over the past three years, global temperatures have risen faster than most climate models predicted, confirming a consensus that warming is accelerating. Some researchers argue the surge reflects systematic model underestimation, while others attribute it to short‑term natural variability that...
Researchers at Sanford Burnham Prebys unveiled TLPath, a machine‑learning model that infers telomere length from routine histopathology slides. The system was trained on 5,263 whole‑slide images covering 18 organs from 919 individuals and can predict telomere shortening in 11 tissue...

The First Proof initiative, a benchmark for large language models in research‑level mathematics, has launched its second round, mandating full transparency from participating AI firms. In the inaugural test, OpenAI and Google DeepMind’s models collectively solved about eight of ten...

Researchers investigated how bubble caps thin and burst, focusing on the buoyant plumes that rise from the foot of the cap where fluid exchange occurs. In still air, these plumes appear as dark‑blue vertical columns, leading to localized thinning. Introducing...
100 years since someone had a crazy idea and believed in it. Only Goddard, his wife Esther, and a couple of assistants witnessed it. It didn't even make the local newspapers, and Goddard kept details secret for years afterward due to...

San Francisco startup Eon Systems announced the first digital simulation of a fruit‑fly brain that can drive a virtual body and produce recognizable behaviors. The model integrates the Flywire whole‑brain connectome—125,000 neurons and 50 million synapses—from an adult female Drosophila, runs...

A multi‑country study of 3,567 participants found riboflavin (vitamin B2) deficiency to be widespread, especially among women and children. Using the erythrocyte glutathione reductase activation coefficient (EGRac) assay, researchers documented deficiency rates of 45%‑90% in high‑ and low‑income nations. In Ireland...
Dutch research institute TNO has spun off Perovion Technologies to industrialise lightweight, flexible perovskite solar cells. The company aims to construct the first roll‑to‑roll perovskite manufacturing line in the Netherlands by 2030, targeting applications where glass panels are impractical. A...
Actually yes. The placenta has been used in medicine for over 100 years. The amniotic membrane is used in eye surgery for corneal reconstruction. It's used as a graft for burn treatment and wound healing. It's used in dental and orthopedic...

Astronauts Zhang Lu and Wu Fei made a spacewalk from the Chinese Space Station from about 0430 UTC until 1135 UTC Mar 16, continuing installation of external debris protection panels https://t.co/GKPg66uFEF

L3Harris Technologies commemorated Robert Goddard’s 100‑year rocket milestone by accelerating next‑generation propulsion, including 3D‑printed RS‑25 engines, advanced electric thrusters, and nuclear thermal concepts. The company is hot‑fire testing new RS‑25 units that cut production costs by 30 percent while delivering...

A polygenic risk score that predicts Type 2 diabetes, obesity, and likelihood for requiring a GLP-1 drug. Across 6 ancestries. https://t.co/5hTVv8kqlK https://t.co/IgXhx8vFA6
Hormesis in action if this study proves correct - a little bit of cell phone radiation may be good for you.
CIEMAT has launched a large‑area multispectral solar simulator designed for precise electrical characterization of full‑size photovoltaic modules. The system delivers better than 0.4% spatial irradiance uniformity, 500 ms LED illumination pulses and dynamic I‑V acquisition, enabling single‑pulse testing of high‑capacitance modules....
The era of digital biology, exemplified by making a bespoke and effective vaccine for cancer in a dog, is taking off. Access to the AI-Coscientist. A new feature @NatureMedicine https://t.co/AR9lqne7E1
Opinions or Facts in Textbooks 💥 See full video here: https://t.co/VXWXNHRiyO #abiogenesis #chemistry #education https://t.co/lKzo8AldPs

The central limit theorem (CLT) explains why bell‑shaped normal distributions appear in everything from rainfall measurements to SAT scores. Originating with Abraham de Moivre’s 18th‑century gambling calculations, the theorem was formalized by Pierre‑Simon Laplace and now underpins modern statistical inference. By...
The Progress MS-31 cargo ship undocked from the ISS Poisk module at about 1324:12 UTC Mar 16

Just weeks ago we didn't know that mutant clones of our aged blood stem cells could be linked to expansion of an aortic aneurysm. No less how. And so much more https://t.co/YuEmJPkdg2 https://t.co/qQq2dgAfWf
The LHCb Collaboration announced the observation of a new baryon made of two charm quarks and one down quark, a particle whose mass is about four times that of a proton. The discovery, presented at the Moriond conference, achieved a...
RIP Paul Ehrlich who made a string of famously apocalyptic predictions in the 1960s and 70s (mass starvation, etc). In 1980, Ehrlich bet Julian Simon that five key metals would rise in price. They didn't. https://t.co/xxFt2N6ptJ
Sarepta tests new Elevidys safeguards; Sana advances diabetes cell therapy https://t.co/hkixuANCCV $SRPT $SANA $INO $BAYRY #biotech
Recent FDA approvals of resmetirom and semaglutide have shifted MASH care from a treatment‑void to a therapeutic reality, prompting sponsors to redesign trial endpoints and enrollment strategies. Non‑invasive diagnostic tools are emerging as potential primary endpoints, reducing reliance on liver...

Association between Low-carbohydrate Diets and 10-year Atherosclerosis Cardiovascular Disease Risk: Data from the National Health and Nutrition Examination Survey https://t.co/NavY2Ldwip https://t.co/Is80ZwaTXu
Researchers at the Cleveland Clinic pursued fragment‑based inhibitors of SARS‑CoV‑2 NSP14, a viral exonuclease essential for replication and immune evasion. Initial crystal‑guided merges appeared active in a biochemical assay, prompting optimism about fragment linking. Subsequent resynthesis and rigorous purification revealed...
Interesting. I wonder if decreased motility is associated with other abnormalities? Could decreased motility be "nature's way" of limiting conception?

Australian researchers have uncovered a previously unknown sulfur‑sulfur rearrangement reaction that proceeds with minimal external input. The finding highlights the versatility of disulfide bonds, which can break and reform in response to diverse stimuli, opening new pathways for peptide, polymer...
Natera announced two peer‑reviewed studies demonstrating the clinical utility of its personalized ctDNA assay, Signatera, in anal squamous cell carcinoma and locally advanced rectal cancer. In the ASCC cohort of 84 patients, baseline negativity or clearance of ctDNA during chemoradiotherapy...
On March 16, 1485 a solar eclipse traced a path from the Pacific across the Atlantic, where it lingered for a maximum of 4 minutes 53 seconds, before moving into Eastern Europe. England experienced only a partial obscuration, but the event coincided with the death...
Elevara Medicines has dosed the first patient in its phase 2b START‑SYNERGY trial, testing the oral CDK4/6 inhibitor ELV001 in rheumatoid arthritis patients who have failed methotrexate and TNF inhibitors. The randomized, placebo‑controlled study will enroll about 180 participants across nine...
Researchers at the University of Illinois Urbana‑Champaign have engineered a photonic‑nanomaterial platform that senses microRNA and DNA signatures linked to cancer up to five to eight years before conventional diagnostics can. The system leverages photonic crystal grating resonance and nano‑assemblies...
A multicenter retrospective cohort of nearly 15,000 low‑risk adults showed that 80% of patients with Lipoprotein(a) above 50 mg/dL did not start any lipid‑lowering medication within 90 days of testing. Initiation of statins was modest, while use of PCSK9 inhibitors and...

University of Minnesota scientists pinpointed structural features of the Marburg virus entry protein that make it up to 300 times more efficient at infiltrating human cells than Ebola’s. By creating a tightly controlled assay, they showed the protein binds the...

Cir‑Code Bio‑med, a Chinese biotech focused on circular RNA medicines, has secured an Investigational New Drug (IND) approval from the U.S. Food and Drug Administration to commence its first human trial. The therapy targets a rare genetic disorder using a...
A Nature Microbiology study reveals that specific Clostridia strains isolated from preterm infants can efficiently metabolize human milk oligosaccharides (HMOs). The bacterial conversion produces short‑chain fatty acids and other bioactive metabolites that suppress pathogenic bacteria and enhance intestinal barrier gene...

Researchers have identified the mathematical rules that enable male fireflies in South Carolina swamps to synchronize their mating flashes. Field experiments using 3D tracking and LED cues revealed that groups larger than fifteen individuals coordinate over several meters via a...
Researchers at DGIST unveiled a dual-modulated vertically stacked transistor featuring a graphene top gate and a micro‑hole bottom gate, achieving off‑state leakage as low as 10⁻¹² A. The design eliminates the need for expensive ultra‑precision alignment and operates at low temperatures,...
Researchers have shown that crystal dislocations in antiferroelectric PbZrO₃ thin films act as nucleation sites for ordered polar anti‑hedgehog lattices. Using atomic‑resolution TEM and phase‑field modeling, they demonstrated that electrostrictive and flexoelectric coupling at dislocation cores generates local electric fields...
A team from Monash and Deakin Universities demonstrated that silicon nanotube arrays can deliver functional mRNA into human induced pluripotent stem cells (hiPSCs) with transfection efficiencies between 55% and 64%. By redesigning nanotube geometry, using low‑molecular‑weight poly‑D‑lysine, and adjusting the...
Researchers at DGIST have demonstrated the first AI semiconductor that uses electrically controlled hydrogen‑ion migration to perform both computation and memory in a vertical two‑terminal device. The hydrogen‑based resistive switching replaces traditional oxygen‑vacancy mechanisms, delivering uniform, stable operation over more...
Researchers at University Medical Center Göttingen employed cryo‑electron tomography to capture near‑atomic structural remodeling of the mitochondrial heat‑shock protein 60 (mHsp60) under proteostatic stress. The protein reconfigures its barrel‑shaped complex, boosting folding activity and preserving mitochondrial function in stressed human...
Researchers at Pacific Northwest National Laboratory used the machine‑learning tool AtomAI to analyze atomic force microscopy images of designed protein nanoribbons on mica. The study discovered that a thin water layer on the mineral surface, not the underlying potassium lattice,...
Pretty impressive data from $gpcr, which remains my favorite ticker. Structure's obesity pill shows weight loss promise in Phase 2 trial https://t.co/T0JU2UuftY

A new ancient‑DNA study of Gothic burial sites reveals that the Goths were a genetically heterogeneous population, drawing ancestry from Scandinavia, the Near East and North Africa. The findings overturn the long‑held view that the Goths originated solely as a...
The Starmus Festival will return to the Canary Islands from October 17‑22, 2026, under the theme “The Search for Truth.” The event, founded by astronomers Garik Israelian and Brian May, will celebrate the 10th anniversary of the Stephen Hawking Medal...
China is targeting a crewed lunar landing by 2030, positioning itself to be the first nation on the Moon since Apollo. The United States, under the Artemis program, has pledged to beat that deadline but still lacks an operational lander...