
High‑altitude hypoxia curbs blood‑sugar spikes in mice
A mouse study found that low‑oxygen (hypoxic) conditions cause red blood cells to absorb far more glucose and convert it into a molecule that eases oxygen release, acting as a glucose sink. Mice exposed to 8% oxygen showed markedly smaller blood‑sugar spikes after glucose injections, and the effect persisted after they returned to normal air.

CERN physicists using the upgraded LHCb detector have identified a new particle, Xi‑cc‑plus, that is four times heavier than a proton. The particle replaces the proton’s two up quarks with charm quarks and decays within a trillionth of a second. Its discovery validates the enhanced detection capabilities of the LHCb upgrade, which spotted the particle after just one year of data. The finding offers a fresh probe of the strong nuclear force that binds atomic nuclei.
The open cluster M29 in Cygnus reaches about 35° altitude in the east around 5 A.M. on March 17, making it a prime early‑morning target for sky‑watchers. Spanning roughly 7 arcminutes and shining at 7th magnitude, it is easily captured with binoculars or...
Io, Jupiter’s innermost Galilean moon, remains the solar system’s most volcanically active world, its eruptions powered by intense tidal heating. A new image captured on March 3, 2026 shows Io transiting Jupiter’s disk, complete with its shadow at the planet’s center. The...
In this episode Chris Kresser reviews a new American Journal of Clinical Nutrition study of over 5,000 Chinese adults aged 80+, which found vegetarians and especially vegans were 19‑29% less likely to become centenarians than omnivores, with the effect driven...

Astronomers have confirmed that interstellar comet 3I/ATLAS carries water and carbon compounds with a deuterium abundance at least ten times higher than any comet observed in our solar system. The comet also shows unusually high carbon‑dioxide levels and is estimated...
Researchers fabricated a novel p‑Ag‑WO3/n‑WO3 nanocomposite diode using chemically synthesized WO3 nanoparticles and a dip‑coating process to create a stable p‑n junction. Electrical characterization—including I‑V, C‑V, and impedance analyses—demonstrated rectifying behavior and effective UV photodetection. The device exhibited space‑charge‑limited current...
UK Atomic Energy Authority (UKAEA) has installed Sunrise, a new supercomputer built on AMD EPYC CPUs and MI 355X GPUs, delivering roughly 6 exaflops at 8‑bit precision and 50 petaflops at 64‑bit. Designed specifically for nuclear‑fusion research, Sunrise merges AI and high‑performance computing...
If you haven’t watched this before, you should. The brilliant Carl Sagan testifying before the United States Congress in 1985 on #ClimateChange. We should have listened then. Will we now? Climate change isn’t an on & off switch. It’s an exponential dial....

Nvidia announces Vera Rubin Space-1 chip system for orbital AI data centers “Orbital data centers have been an increasingly popular proposition as AI demand tests Earth's energy constraints.” https://t.co/fWrKyLiAij #SpaceEconomy https://t.co/SBqD6vmYbz
Temporal interference (TI) stimulation uses two high‑frequency electrical currents that intersect to generate a low‑frequency envelope capable of modulating deep‑brain activity without surgery. Early human pilots have reported seizure suppression and better sleep in epilepsy, improved motor learning after stroke,...
looking forward to concluding next week's NAD for Health conference in Copenhagen with a talk on Known Knowns and Known Unknowns in NAD Coenzyme Research.... see you there https://t.co/hLAnAq7Fay

Injectable peptides such as BPC‑157, GHK‑Cu and TB‑500 have surged in popularity among biohackers despite lacking regulatory approval. The Guardian podcast explores why these grey‑market compounds have become mainstream, featuring insights from journalist Adrienne Matei and Imperial College peptide researcher...
🧪⚛️ A brief write-up of random highlights from Day 1 of the big annual APS Global Physics Summit (formerly known as the March Meeting). https://t.co/tO5dvFZm3Q
The APS March Meeting Day 1 showcased cutting‑edge research on quantum excitations and emergent materials. Highlights included Hanyu Zhu’s demonstration of chiral phonons producing intense local magnetic fields, and talks on cavity‑magnon control using surface acoustic waves for nonreciprocal devices. Longji...
Pakistan’s rapid adoption of solar power in the past few years is helping cushion the impact of a surge in fossil fuel prices due to the Middle East war https://t.co/4eyTCuM5KW
Early‑stage breast cancer patients face a lingering concern about recurrence, which can be local, regional, or distant. Dr. Margaret Thompson explains that recurrence rates have fallen over the past two decades thanks to improved surgery, radiation, and systemic therapies. Individual...

David Sussillo’s memoir recounts how a chance email linked him to Larry Abbott, whose mentorship at Columbia’s Center for Theoretical Neuroscience led to the development of FORCE learning. The method trains chaotic recurrent neural networks by harnessing their intrinsic dynamics...

Leucovorin prescriptions for autistic children jumped 71% after a White House briefing promoted the drug, yet the FDA only approved it for cerebral folate deficiency and withdrew any autism claim. A 2024 autism trial supporting leucovorin was retracted, casting doubt...

Recent research links chronic high‑fat consumption to elevated cortisol and gut‑derived serotonin, which together compromise the intestinal barrier and spark systemic inflammation. The studies show that excess dietary fat disrupts gut microbiota, increasing pro‑inflammatory Firmicutes and endotoxin‑producing Gram‑negative bacteria while...

Recent research published in Molecular Psychiatry and related journals shows that gut dysbiosis can weaken dopamine‑reward circuits and reduce synaptic connectivity in the medial prefrontal cortex of mice receiving microbiota from bipolar‑depressed patients. The same studies report distinct microbial signatures...

A bright fireball streaked across the sky over Hawke’s Bay early Thursday morning, prompting witnesses to think it was a plane or meteor. Observers from Wairoa to Napier reported a slow‑moving white object leaving a lingering contrail lasting up to...
Jo Marchant’s new book explores how the brain constructs the present moment by constantly predicting future sensory input. Neurological cases like akinetopsia and schizophrenia illustrate how disrupted predictive processing warps time perception. The author links these mechanisms to Bayesian inference,...

Astronomers have identified a planet 35 light‑years away that does not fit existing small‑planet categories. The world, L 98‑59 d, was first discovered in 2019 and observed by JWST in 2024 and ground facilities in 2025. Researchers used computer models to simulate...
NeuroScientific Biopharmaceuticals has begun its first manufacturing run of the StemSmart mesenchymal stem cell therapy at Q‑Gen Cell Therapeutics in Brisbane, initiating a critical technology transfer. The engineering run will validate quality, potency and regulatory compliance ahead of a Phase 2...

Why do women account for nearly 2/3rd of all cases of Alzheimer's disease? A new, thorough review @jclinicalinvest, open-access, on its origins in midlife. https://t.co/obITwhEiYG https://t.co/RXBffM9jKV
A Nature paper published March 17, 2026 presents the first cryo‑electron microscopy structure of the mammalian oocyte cytoplasmic lattice (CPL). The study identifies fourteen constitutive protein subunits and describes a repeating architecture built from U‑shaped basket (UB) and adapter ring...
Researchers built a whole‑brain atlas of 38 neuropeptide‑receptor genes, mapping their expression across 455 cortical, subcortical and hypothalamic regions. The receptors display a clear cortical‑subcortical gradient and two principal axes within hypothalamic nuclei that reflect developmental organization. Spatial overlap analysis...
Ionis Pharmaceuticals announced that its Phase 1/2a PrProfile trial of ION717, the first PrP‑lowering antisense oligonucleotide for symptomatic prion disease, has reopened with a third dosing regimen. The study, which enrolled 56 patients in 2024, will now recruit at three...
Researchers at Westlake University have demonstrated an anode‑free lithium‑metal pouch cell that reaches 508 Wh kg⁻¹ energy density by using a crossover‑coupled electrolyte. The electrolyte creates a boron‑fluorine polymer‑rich solid‑electrolyte interphase (SEI) that is sub‑nanometer homogeneous, flexible, and enables uniform planar lithium...
Researchers have demonstrated a perovskite‑perovskite‑silicon triple‑junction solar cell that reaches a certified 30.02 % power conversion efficiency on a 1 cm² substrate. The breakthrough combines a non‑volatile additive, 4‑hydroxybenzylamine, which aligns crystal growth and suppresses non‑radiative recombination in the wide‑bandgap top cell,...
China’s Shenzhou‑21 crew completed a second seven‑hour EVA, installing a new space‑debris protection device on the Tiangong station. Astronauts Zhang Lu and Wu Fei performed the walk with assistance from the station’s robotic arm and fellow crew member Zhang Hongzhan. The mission also...

A new Lancet Global Health study links rising temperatures to a measurable decline in physical activity worldwide. Each additional month with average temperatures above 27.8 °C raises inactivity by 1.5 percentage points globally, and 1.85 points in low‑ and middle‑income nations. By...
A systematic review published in Lancet Psychiatry, analysing 54 randomized controlled trials from 1980‑2025, found no evidence that medicinal cannabis treats depression, anxiety or PTSD. The paper highlights modest benefits for conditions such as epilepsy, multiple sclerosis spasticity, pain and...

A UCLA Health study links long‑term residential exposure to the pesticide chlorpyrifos with a more than 2.5‑fold increase in Parkinson's disease risk. Researchers analyzed 829 Parkinson's patients and 824 controls, estimating exposure through California pesticide records, and corroborated findings with...
Science just explained what's actually happening in your body during a great conversation. When two people are truly in sync, their bodies and brains are literally starting to function alike, and that's exactly what great communication is designed to do....
Air conditioning is an energy hog, right? Right. But there are also incredibly low-energy ways to cool buildings - by literally sending their waste heat into space.
The latest seasonal outlooks for Canada’s Prairies show a patchwork of temperature and precipitation signals across March‑May. While the Old Farmer’s Almanac and NOAA suggest near‑average warmth and rain, the CFS model leans toward a warm end‑March, cooler April, and...
The aged amygdala’s unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis https://t.co/0eVLV5Kual
Brazil's revised climate plan focuses on stopping deforestation as the key to driving down emissions https://t.co/Zvg9D2XifC
Researchers at the University of Colorado Boulder have created a light‑controlled hydrogel that closely replicates the softness and viscoelastic behavior of human tissue. The material can be solidified or softened on demand using photopolymerization, allowing precise spatial control during 3‑D...

Since some of the most horrid individuals on this medium are working hard to smear Paul Ehrlich on his passing, here's some relevant background on Paul and his legacy from "The Hockey Stick & the Climate Wars" (https://t.co/y6lplWKpsL) https://t.co/Zu3kNa9C0E
Researchers at Cardiff University found that severe DNA mutations called chromoanasynthesis happen when broken chromosomes are repaired using small DNA fragments, causing chaotic duplications that can drive cancer and genetic diseases. 🧬https://t.co/Q9j2hRezTs
Researchers at the Wyss Institute have created the first “neurobots,” living robots built from frog embryonic cells that incorporate neuronal precursor cells to form self‑organizing nervous systems. The neurobots develop mature neurons that connect internally and extend processes to surface...
German startup Isar Aerospace is set for the second flight of its Spectrum launch vehicle, dubbed “Onward and Upward,” from Andøya Space in Norway on March 19. The mission marks the rocket’s first customer payload flight, carrying five CubeSats and a...

The CARPOOL observational study compared radial‑to‑peripheral (R2P) and femoral access for peripheral artery disease (PAD) interventions and found comparable 30‑day major adverse limb event (MALE) rates. While radial access achieved a technical success of 87.2% versus 94.9% for femoral, it...

A joint effort by EMBL‑EBI, Google DeepMind, NVIDIA and Seoul National University has added millions of AI‑predicted protein complex structures to the AlphaFold Database, marking the largest collection of such data to date. The release focuses on high‑confidence homodimers, delivering...
Illumina unveiled Illumina Connected Multiomics, a cloud‑based platform that unifies single‑cell, spatial transcriptomics, proteomics, and methylation data for large‑scale analysis. The system aggregates thousands of samples from Illumina and third‑party assays, delivering reproducible results through DRAGEN secondary analysis. AI‑driven tools...

Researchers found that women who experienced an adverse pregnancy outcome (APO) and reported high psychosocial stress had significantly higher diastolic blood pressure 2–7 years postpartum, whereas stress alone did not affect blood pressure in uncomplicated pregnancies. The analysis of 3,322...
A study in Alzheimer's & Dementia found that late-life methionine restriction reduces Alzheimer’s pathology and neuroinflammation in mice by activating the liver–brain FGF21–FGFR1 signaling pathway, independent of metabolic improvements. 🧠 https://t.co/A9kEqNv8pO
Researchers at KRICT, Hanyang University and Sejong University have unveiled the world’s first 4D‑printing platform that uses sulfur‑rich polymers derived from petroleum‑refining waste. By engineering a loosely cross‑linked sulfur polymer network, the material can be extruded, printed, and programmed to...