Know What's Happening in Science
Know What's Happening in Science
High‑altitude hypoxia curbs blood‑sugar spikes in mice
A mouse study found that low‑oxygen (hypoxic) conditions cause red blood cells to absorb far more glucose and convert it into a molecule that eases oxygen release, acting as a glucose sink. Mice exposed to 8% oxygen showed markedly smaller blood‑sugar spikes after glucose injections, and the effect persisted after they returned to normal air.
Researchers at Japan’s National Agriculture and Food Research Organization engineered an anhydrobiotic Pv11 cell line to express the fruit‑fly odorant receptor Or47a and calcium‑sensitive reporter GCaMP6f. The resulting Pv11‑00443‑Or47a cells kept the insect’s extreme desiccation tolerance, enabling dry storage at room temperature for up to three years. After rehydration, they showed dose‑dependent fluorescence to pentyl acetate with EC50 values of 3‑8 µM, matching fresh‑cell performance. This proves that long‑term, refrigeration‑free, cell‑based odor sensors are feasible for portable use.
New computer simulations suggest the Small Magellanic Cloud (SMC) passed directly through the Large Magellanic Cloud (LMC) about 200 million years ago, explaining the chaotic stellar motions observed in the SMC. Measurements from Hubble and Gaia showed the SMC’s stars lack...
A new Cochrane review claims intermittent fasting "doesn't work." But it only measured weight loss - not insulin sensitivity, autophagy, inflammation, or gene expression. Here's what the science actually shows. The 2026 Cochrane systematic review analyzed 22 randomized controlled trials and...
NASA is gearing up for the X‑59 quiet‑supersonic research aircraft's second flight, slated for this week from the Armstrong Flight Research Center at Edwards, California. The one‑hour mission will cruise at roughly 230 mph at 12,000 ft before climbing to 20,000 ft and...
Thomas Eugene Johnson The field of aging genetics lost one of its pioneers. Tom Johnson's identification of the age-1 mutant allele in C. elegans was a landmark moment, showing that a single genetic change could dramatically extend lifespan. That discovery helped...
Avian influenza has been confirmed in a common murre that died at Point Reyes National Seashore, marking the disease’s arrival in the park. The incident is linked to a larger seabird mortality event across the San Francisco Bay Area. Park biologists...
Sanofi unveiled pre‑clinical data for an in‑vivo CAR‑T platform that delivers mRNA via lipid nanoparticles (LNPs) and a CD8‑targeting VHH nanobody, eliminating the weeks‑long ex‑vivo manufacturing step. The approach achieved tumor suppression in mice with less than 5% liver uptake...
A study in Cell Reports identifies Munc13‑1 as a calcium‑sensing molecular sensor that drives short‑term synaptic strengthening essential for working memory. Using knock‑in mice, researchers showed that disrupting calcium‑phospholipid or calcium‑calmodulin pathways in Munc13‑1 impairs post‑tetanic potentiation and short‑term facilitation...
Researchers at National Taiwan University have unveiled a hybrid nanocomposite that merges graphene oxide, biochar, and titanium dioxide to tackle antibiotic residues in wastewater. The material leverages both adsorption and UV‑activated photocatalysis, achieving over 95% removal of veterinary antibiotics such...
GIP preferentially enhances glucose storage and triglyceride deposition in healthier subcutaneous fat, particularly under conditions of hyperinsulinemia and hyperglycemia. Tirzepatide contains a GIP agonist. https://doi.org/10.2337/db10-0098 https://www.gatlan.com/ @GatlanHealth
NASA is reconsidering the south‑pole for Artemis’s first crewed landing, exploring alternative sites to reduce risk and accelerate timelines. Associate Administrator Amit Kshatriya said performance specs are being opened to allow different lunar orbits and constraints. Administrator Jared Isaacman pushes...
ISPTech, a German spin‑off from the DLR, announced a €5.5 million seed round led by Join Capital and backed by several European venture funds. The capital will fund expanded manufacturing, critical‑infrastructure testing, and the commercial rollout of its non‑toxic propulsion suites,...
Researchers analyzing NASA nighttime satellite data found that 44 major U.S. cities exhibit higher cloud cover than surrounding rural areas, with increases ranging from under 1% to about 15%. The study linked these differences to urban design, showing that taller...
Researchers at Humboldt‑Universität and the Ferdinand‑Braun‑Institut have demonstrated the SUPER (Swing‑UP of the quantum EmitteR population) method for generating single photons from diamond tin‑vacancy (SnV) centers. The technique employs two precisely timed femtosecond laser pulses to excite the qubits while...
The International Probiotic Conference (IPC) 2026 in Kraków is now accepting oral and poster abstracts, with deadlines of April 24 and May 1, 2026 respectively. Selected presenters will share cutting‑edge research on probiotics, prebiotics, microbiome modulators and related therapies to an international audience....
In this episode, host Volime Vesela, a physician‑scientist and CEO of Bexerg, discusses his startup’s groundbreaking work reviving dead human brains to create an intact human brain lab for drug testing. He explains how his Croatian co‑founder, Dr. Josep "Joe"...
SpaceX completed two Starlink missions within 24 hours, launching 25 satellites from Vandenberg and 29 from Cape Canaveral. Both Falcon 9 first stages were recovered, marking the 14th and 11th flights of the boosters after turn‑arounds of 32 and 27 days....
Jihyeon Park and colleagues introduced CANOE, a Classically Assisted Non‑Orthogonal Eigensolver that distributes the computational load between quantum and classical hardware. By combining a few highly entangled quantum basis states with a large pool of classical determinants, the method reaches...
The New York Times reports that the Thwaites Glacier in Antarctica is destabilizing faster than anticipated, raising the specter of a multi‑foot sea‑level rise. Scientists warn that a full collapse could add up to three feet to global oceans by...
Quantum Design Oxford and the National High Magnetic Field Laboratory have announced a strategic partnership to co‑develop superconducting magnets that reach 20‑30 Tesla. The collaboration leverages MagLab’s Bi‑2212 high‑temperature superconductor wire and a high‑pressure reaction technique with Quantum Design Oxford’s commercial...
Cycling aerodynamics research reveals that certain bike frames and wheels generate a "sail effect" in cross‑winds, reducing drag and even producing forward thrust. Tests by Cyclingnews Labs showed deep‑tube frames like the Factor ONE and disc wheels achieve lower drag...
A study asserts lack of disproportionate loss of muscle mass or strength cf weight loss from GLP-1 drug treatment, in mice and a small short term (12 weeks) trial in men The issue remains unsettled and counters the efforts by companies...
It is honestly scary that microplastics are now being found in human placentas, amniotic fluid, breast milk, and even testicular tissue. A 2024 study found microplastics in every single one of the 62 placentas they tested. The plastics in your...
South Korean rocket startup Innospace released its investigation into the Hanbit‑Nano maiden‑flight failure on December 22, 2025. The probe identified a rupture in the first‑stage combustion‑chamber assembly 33 seconds after liftoff, caused by a leakage from improperly sealed components. The leakage stemmed...
From Prof Jin and my colleagues @scrippsresearch the largest in vivo CRISPR data engine, nearly 8 million cells, in collaboration with @nvidia and featured at GTC
Pfizer’s Ibrance successor moves forward with new study data https://t.co/ozXAZYmc3M by Kristin Jensen $PFE $LLY $NVS $RHHBY $ONC
More than five decades after the ariel toucan was reintroduced to Rio de Janeiro’s Tijuca National Park, a year‑long study shows the bird has largely resumed its historic ecological role. Researchers documented toucans feeding on 76 % of the 101 native...
An international expert panel has recommended that the intrathecal kappa free light chain (κ‑FLC) index be added to the next revision of multiple sclerosis (MS) diagnostic criteria as a quantitative, cost‑effective alternative to oligoclonal bands (OCBs). κ‑FLC can be measured...
Scientists at Sanford Burnham Prebys and UCLA unveiled metapipeline‑DNA, a new computational tool that automates quality control, variant calling, and reporting for large‑scale genome sequencing. The pipeline processes roughly 100 GB per human genome and can scale to hundreds of samples,...
When ice forms in salty water it initially creates a mushy, porous matrix as brine becomes trapped between crystal lattices. Over roughly sixteen days, the denser brine convects downward, expelling itself and leaving a thinner yet more solid ice layer...
Biodegradable polymers are emerging as versatile carriers for immunotherapeutic agents, offering tunable degradation, enhanced antigen presentation, and intrinsic immunomodulatory properties. The review evaluates synthetic and natural polymers such as PLGA, PBAEs, Ace‑DEX, chitosan, alginate, and hyaluronic acid, highlighting their formulation...
Researchers have engineered biomimetic nanocarriers that combine liposomal structures with Myxobacteria outer‑membrane vesicles (OMVs) to deliver antibiotics. The hybrid carriers achieve higher drug loading and can penetrate intracellular Gram‑negative pathogens, while native OMVs avoid immune clearance and sustain extracellular exposure....
Researchers introduced an N‑methyl‑2‑pyrrolidone (NMP)‑mediated self‑assembly method that leverages π–π stacking to fabricate highly uniform polyaniline/reduced graphene oxide (PANI@RGO) composite gels with up to 85 % polyaniline loading. The resulting M‑PANI@RGO‑85 % cathode exhibits a specific surface area of 189.55 m² g⁻¹ and mesopores...
The review highlights how bacterial membrane composition critically shapes the activity of antimicrobial peptides (AMPs) and outlines experimental and computational strategies for their rational design. By examining case studies, it maps structure‑activity relationships that govern membrane disruption versus intracellular targeting....
A new review outlines recent progress in hybrid 3D bioprinting that combines inkjet, extrusion, and vat photopolymerization to fabricate multiscale tissue constructs using sustainable, renewable biomaterials. The authors highlight how integrating multiple printing modalities overcomes single‑technique limitations, enabling nano‑ to...
Researchers have engineered recombinant suckerin‑12 colloids and hydrogels that act as wet‑resistant tissue adhesives. The materials exhibit stronger adhesion than traditional mussel‑derived proteins and outperform fibrin glue in hemostasis, cell proliferation, and wound closure in animal models. Low cytotoxicity, minimal...
Horizons Podcast: Climate Science in an Age of Uncertainty | My recent conversation with @PennSAS Dean Mark Trodden https://t.co/8Ocy4Bk1Tg
You should placebo yourself into thinking you’re on steroids. Athletes given a placebo they thought was Dianabol added ~8.5 kg to their bench, ~7 kg to their military press, and ~16 kg to their squat in 4 weeks compared to when...
NASA released X‑ray computed tomography scans of asteroid Bennu samples on March 17, 2026, revealing intricate crack networks inside the material. The scans show that Bennu’s boulders are highly porous, a property that accounts for the low thermal inertia measured...
Neurodegenerative diseases at the single-cell level, a powerful tool to differentiate and better understand https://t.co/Pkz4qW0ELM @jclinicalinvest https://t.co/LiJ4FojRYZ
A University of Geneva team discovered that children with 22q11.2 deletion syndrome show reduced glymphatic clearance, a brain waste‑removal system, and that this early dysfunction predicts the emergence of psychotic symptoms in adulthood. Using longitudinal diffusion‑tensor imaging and magnetic‑spectroscopy, the...
Evolution professor Luana Maroja surveyed her undergraduate class on how many biological sexes exist in animals and plants. The majority (44%) chose four sexes—males, females, intersexes, and hermaphrodites—while only 21% correctly identified the binary gamete‑based definition. The results highlight persistent...
CEA‑Leti will present seven papers at IRPS 2026, covering device physics, process integration, RF, FD‑SOI, GaN, BEOL reliability and low‑temperature 3‑D sequential integration. The work combines advanced characterization techniques with physics‑based modeling to deliver early‑stage reliability insights for designers. Highlights include...
A great read: What we can learn from evolving proteins "A signal hidden in Mulitple Sequence Alignments (MSAs): amino acid positions that tend to co-vary in the MSA tend to interact with each other in the folded structure, often via direct...
NE Ohio just got hit with a meteorite, heard it from all over .. I think it was a truck unloading by our house. Looks like everyone's OK
The editorial challenges the long‑standing belief that increasing muscle strength is the primary driver of pain relief in exercise‑based rehabilitation for musculoskeletal conditions. It reviews systematic reviews and mediation analyses across Achilles tendinopathy, patellar tendinopathy, rotator‑cuff shoulder pain, patellofemoral pain,...
Experimental particle physicist Dave Newbold has been elected co‑spokesperson of the Deep Underground Neutrino Experiment (DUNE) for a two‑year term starting April. Newbold, currently STFC’s executive director of national laboratories, has been involved with DUNE since 2015, contributing to data...
The United States faces a transplant shortage of over 100,000 patients, prompting research into xenotransplantation using genetically engineered pig organs. Recent cases—David Bennett’s pig heart in 2022, Lawrence Faucette’s in 2023, and Tim Andrews’ pig kidney in 2025—demonstrate feasibility, with...
1/ You think the biggest danger in genomics is bad data. More than that. It's the mistakes you make—without knowing. Here are the ones I learned the hard way. 🧵 https://t.co/3oj9cseVq7
Researchers led by Abdul Sami Rao examined street networks from Islamabad and Lyari, showing that planned grid topologies dramatically improve the Approximate Optimisation Algorithm (QAOA) at shallow depth p=1. Islamabad’s layout achieved 95% reliable convergence on the minimum vertex cover...
