Novel Phage Effectively Inhibits Antimicrobial-Resistant Salmonella, Biofilms on Food, Surfaces
Researchers at Gansu Agricultural University have identified a novel lytic bacteriophage, W5, that effectively targets antimicrobial‑resistant Salmonella across multiple food matrices. The phage remains stable at temperatures up to 50 °C and across a pH range of 3‑13, achieving 98% host adsorption within 13 minutes. In milk, eggs and pork, W5 markedly reduces Salmonella growth and both prevents and eradicates biofilms on common processing surfaces. Whole‑genome sequencing confirmed the absence of virulence, antibiotic‑resistance and lysogenic genes, supporting its food‑grade status.
Are the Bees Still Dying? The Scary Truth Behind the Continuing ‘Beepocalypse’
After two decades of alarm over honeybee die‑offs, the crisis has not vanished. Nationwide data show commercial beekeepers lost 62 % of their colonies this past winter, while average winter losses over the last 20 years hover between 30 % and 40 %. Colony...
Precision Medicine in Early Oncology Trials: Biomarkers as Strategic Drivers
Oncology drug development is shifting toward precision immunotherapies, with biomarkers driving patient selection and trial efficiency. Experts at a Caidya webinar highlighted two trends: novel combination regimens and early integration of biomarker strategies, including companion diagnostics. Early biomarker adoption can...
Repeated Identification of Two Novel Poleroviruses in the Virome of French Grain Cereals
A five‑year metagenomic survey of French wheat and barley identified two novel poleroviruses, including barley virus H (BVH), which appears in 2.3 % of samples. BVH shares typical polerovirus genome organization but lacks ORF6 and ORF7, distinguishing it from known species. The...
Addressing Pain Points in Organoid Sorting: The Orgadroid
Visienco, a Swiss life‑sciences startup, unveiled the Orgadroid—an automated platform that combines precision robotics with AI‑driven microscopy to sort and classify organoids. The organoid market is forecast to reach $15.01 billion by 2031, growing at a 22.43% CAGR, but manual handling...
Amgen’s Lung Cancer Drug Tarlatamab Wins China Approval
Amgen’s bispecific antibody tarlatamab, marketed in the U.S. as Imdelltra, has received approval from China’s National Medical Products Administration. The drug is designed for adults with extensive‑stage small cell lung cancer that has progressed despite chemotherapy. Amgen will commercialize the...
Why Fundamental Research in Photovoltaics Remains Critical for an Established Technology
A new paper led by Professor Rebecca Saive of the University of Twente warns that fundamental research in photovoltaics is losing traction as scientists drift toward other fields. The authors cite a 15% drop in dedicated funding over the past...
Artemis Astronauts to Shed Light on Space Health Risks
NASA's Artemis II mission sent four astronauts on a lunar flyby, exposing them to deep‑space radiation levels far beyond those in low‑Earth orbit. The agency equipped Orion with radiation sensors, collected blood, saliva, and smartwatch health data, and installed bio‑mimetic chips...
The Sky Today on Friday, April 10: Ganymede Shadow Crossing
Early Friday morning, the large shadow of Jupiter’s moon Ganymede began crossing the planet’s cloud tops, becoming visible across the western two‑thirds of the United States at 12:57 A.M. CDT. The dark notch takes about eight to ten minutes to fully...
Multi-Agent AI Delivers Reliable and Scalable Insights for Single-Cell Omics
Nygen Analytics, a Lund‑based startup founded by computational genomics expert Parashar Dhapola, is deploying multi‑agent AI to streamline single‑cell omics analysis. The platform automates cell‑type annotation, handling millions of cells while reducing error rates that can misguide drug discovery. By...
How Do You Replace 40 Million Dead Vultures?
India has lost an estimated 40 million vultures over the past two decades, crippling a critical public‑health service. The Jatayu Conservation Breeding Centre, the world’s largest vulture‑breeding facility, is attempting to restore populations by raising thousands of birds each year. However,...
Europe and China Are Running a Joint Space Mission in an Era When They Agree on Almost Nothing
Europe’s ESA and China’s Academy of Sciences are set to launch the 2.3‑tonne Smile satellite from French Guiana on a Vega‑C rocket later this month. The spacecraft will travel to an elliptical orbit with a 121,000 km apogee over the North...
Iron‐Based Metal‐Organic Framework MIL‐100(Fe) Regulates Keloid Scarring in a Humanized Keloid Model
The study shows iron‑based metal‑organic framework MIL‑100(Fe) nanoparticles are highly biocompatible, rapidly taken up by keloid fibroblasts, and selectively inhibit the TGF‑β/SMAD pathway, reducing collagen I, collagen III, and P4HA1 expression. In vitro experiments maintained >90% cell viability and curtailed...
What You Would See and Feel While Traveling Near the Speed of Light
The ScienceClic animation illustrates how a spacecraft would look when accelerating toward light speed, emphasizing that only the acceleration phase poses a physiological risk. As velocity climbs, relativistic aberration squeezes the star field into a bright forward cone while the...
Impact of Zn and Te Vacancies on the Electronic and Magnetic Properties of ZnTe Nanosheet
The study uses first‑principles density‑functional theory to explore how intrinsic zinc (Zn) and tellurium (Te) vacancies alter the structural, electronic, and magnetic behavior of two‑dimensional ZnTe nanosheets. Introducing a Zn vacancy converts the nanosheet into a half‑metallic state with 100 %...
ISRO Successfully Conducts Second Integrated Air Drop Test for Gaganyaan Mission
India’s space agency ISRO completed its second integrated air‑drop test (IADT‑02) for the Gaganyaan crewed mission at the Satish Dhawan Space Centre in Sriharikota. The test dropped a 4.8‑tonne dummy capsule from three kilometres using a Chinook helicopter, validating the...
PH‐Controlled Synthesis of SnO2 Electron Transport Layers for High‐Efficiency and Stable Perovskite Solar Cells
Researchers demonstrated that the pH used during SnO₂ synthesis dramatically shapes its surface chemistry and, consequently, perovskite solar‑cell performance. Acidic SnO₂ (AC‑SnO₂) bears carboxyl groups that form strong hydrogen bonds with FA⁺ but accelerate iodide oxidation, while alkaline SnO₂ (AL‑SnO₂)...
Synergistic Enhancement of Optical Anisotropy in Nitrate Sulfamate for UV Applications: Role of Functional Group Alignment and Hydrogen Bond Network
Researchers synthesized four novel nitrate sulfamate crystals using a design strategy that orders cation sites and creates a three‑dimensional hydrogen‑bond network. This structural control aligns NO3 and SO3NH2 groups in parallel, boosting birefringence to >0.1 at 546 nm for K2(NO3)(SO3NH2), Rb2(NO3)(SO3NH2)...
Design and Application of a Photo‐Thermal Dual‐Curable Resin for Architected Microwave Absorbers in the X‐Band via DLP Printing
Researchers have engineered a photo‑thermal dual‑curable resin that can be shaped by DLP 3D printing and then thermally post‑cured, delivering a low dielectric constant (ε′<3.0), ultra‑low loss (tan δ<0.01), glass transition above 200 °C and tensile strength over 80 MPa. The resin was...
Bidirectional All‐Optical Synapses for Neuromorphic Computing and Vision
Researchers have created a bidirectional all‑optical synapse using a carbon‑dot hybrid (CDH) that responds to both ultraviolet and infrared light. The dual‑photon approach enables controllable exciton release and phosphorescent emission, delivering true optical potentiation and depression. Leveraging this capability, the...
![[Perspectives] Mammography Should Include Artificial Intelligence Support](https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/a8b50d033d7e546335a6ec09b92b1dc2.webp)
[Perspectives] Mammography Should Include Artificial Intelligence Support
The Mammography Screening with Artificial Intelligence (MASAI) randomised trial showed that a single radiologist assisted by an AI algorithm achieved higher sensitivity than the traditional double‑reading approach, while preserving specificity. Complementary studies from 2025‑2026 confirm AI’s scalability and equitable performance...
![[Correspondence] Contemporary Non-Invasive Imaging for Coronary Artery Disease](https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/e5f5d89f21057c303d0efa1bf29145af.webp)
[Correspondence] Contemporary Non-Invasive Imaging for Coronary Artery Disease
The correspondence highlights three critical clarifications to a recent review on non‑invasive cardiac imaging. First, it stresses that patients with non‑obstructive coronary arteries can still experience angina and ischemia due to microvascular dysfunction or vasospasm. Second, it reinterprets the role...
![[Obituary] John Bertrand Gurdon](https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/5811bed8c2fa1ae7323ccc02f30cf842.webp)
[Obituary] John Bertrand Gurdon
Sir John Gurdon, a pioneering developmental biologist and 2012 Nobel laureate, died at 92. He proved that mature cells retain the full genetic blueprint by cloning a frog from an adult intestinal cell, overturning the belief that differentiation was irreversible....
![[Comment] Liver Disease: Screening for the Elusive Adversary](https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/78ddd2d9226c22494f867b221566624c.webp)
[Comment] Liver Disease: Screening for the Elusive Adversary
The Lancet commentary revisits the classic Wilson‑Jungner criteria to evaluate whether population‑wide liver disease screening is justified. It highlights the disease’s long asymptomatic phase and dismal outcomes for late presenters, but points out the lack of consensus on diagnostic thresholds...
Imagene AI Partners with Daiichi Sankyo to Advance Multimodal Biomarker Discovery in Oncology
Imagene AI has teamed up with Daiichi Sankyo to use its OI Suite, powered by the CanvOI foundation model, for multimodal biomarker discovery in oncology. The collaboration will integrate H&E and IHC whole‑slide images with molecular and clinical data to...
Oklahoma Just Released a Captive Whitetail Deer Into the Wild...On Purpose
Oklahoma has released its first captive‑raised whitetail deer into the wild as part of a 2024 legislative program aimed at slowing chronic wasting disease (CWD). The animal meets genetic criteria for CWD resistance but was not tested for the disease...
NASA Managers Outline Artemis 2 Reentry and Address Propulsion Issue Ahead of Splashdown
NASA mission managers held a final status briefing ahead of Artemis 2’s splashdown, confirming the Orion crew capsule will reenter Earth’s atmosphere at roughly 40,233 kph (25,000 mph) and endure heat comparable to the Sun’s surface. The briefing detailed a tight reentry timeline,...
Blastoff — a Moment of Hope, From Space
NASA’s Artemis II mission completed a historic 10‑day lunar flyby, marking the farthest human spaceflight to date. The Orion crew, including pilot Victor Glover, reported a unifying view of Earth from the spacecraft’s windows. The flight tested critical launch and navigation...
Laser Firm 'over the Moon' To Play a Part in Artemis II Space Mission
Welsh laser specialist Spectrum Technologies supplied laser‑marked wiring for NASA’s Artemis II Orion capsule, the first Welsh‑made component on a crewed lunar fly‑by. The company’s machines printed unique alphanumeric codes on 32 km of wiring, enabling reliable identification of thousands of wires....
This Alzheimer's Risk Gene Rewires Your Brain Long Before Symptoms – and One Surprising Habit Could Blunt Its Impact
Scientists have identified that the APOE4 allele, which raises Alzheimer’s risk three‑ to four‑fold per copy, rewires hippocampal memory circuits in mice decades before any cognitive symptoms appear. Young APOE4 mice exhibit smaller, hyper‑excitable neurons, a pattern not seen in...
More than Half of the US in Drought After Near-Record March Temperatures
A near‑record heat wave in March pushed more than half of the contiguous United States into drought, according to the U.S. Drought Monitor. Roughly 55% of the country now faces moderate to severe dryness, with the Southwest and Great Plains...
Error Equation Predicts Brain’s Ability to Generalize
The study published in Nature Neuroscience proposes a single error equation that links the geometry of neural population activity to the brain’s capacity to generalize across tasks. By extracting four geometric metrics—task‑related correlation, dimensionality, signal‑to‑noise factorization and signal‑signal factorization—the authors...
Debris or Destiny: How Megaconstellation Operators Are Rewriting the Rules of Orbital Sustainability
Megaconstellation operators are reshaping orbital sustainability as low‑Earth‑orbit congestion surges. In 2025 Starlink alone executed roughly 300,000 collision‑avoidance maneuvers, while the CRASH Clock metric indicates close‑encounters are now 100 times more frequent than in 2018. SpaceX plans to lower 4,400 satellites...
Scientists Develop Three-in-One Diode
Researchers at the University of Science and Technology of China have unveiled a GaN‑based PN junction photodiode that simultaneously handles photosensing, memory storage, and processing. By inserting an n‑AlGaN charge‑storage layer, the device can switch among three functional modes using...
Marktech Launches High Power 280nm UVC LEDs
Marktech Optoelectronics has introduced a family of high‑power 280 nm UVC LEDs available in single‑, two‑ and four‑chip formats. The devices deliver wall‑plug efficiencies up to 7% and are rated for more than 15,000 hours at the L70 degradation point. By...
Japanese Team Achieves 2 Μm-Band PCSEL Laser Oscillation
Asahi Kasei Microdevices (AKM) and Kyoto University have demonstrated laser oscillation in a 2 μm-band photonic crystal surface‑emitting laser (PCSEL). The breakthrough showcases PCSEL’s ability to deliver high directionality and ultra‑narrow linewidth in a compact infrared source. By operating at 2 μm,...
QuinAs Links Memory Device Physics to AI Performance
QuInAs Technology has published research linking its ULTRARAM compound‑semiconductor memory device directly to AI system performance. The paper introduces a physics‑based compact modelling framework that captures resonant tunnelling and floating‑gate dynamics, enabling hardware‑aware benchmarking of ULTRARAM as a synaptic element...
Half of Seabirds Are Declining. Protecting Marine Flyways Could Help Save Them
A new study maps six global marine flyways used by 151 seabird species—about 40% of all seabirds—showing that nearly half of migratory seabirds are in decline. These routes cross the Exclusive Economic Zones of 54 countries, with France intersecting all...
Earliest Known Vomit: This Ancient Predator Clearly Wasn't Picky
Paleontologists identified a 290‑million‑year‑old fossilized vomit (regurgitalite) from the early Permian Bromacker site in Germany. The 2‑inch clump, designated MNG 17001, contains 41 tiny bones from at least three prey species, including the reptile Thuringothyris mahlendorffae, the bipedal Eudibamus cursoris, and...
Far Away Objects
Artemis II has set a new record for the farthest distance traveled by a crewed spacecraft, reaching a peak of 406,771 km from Earth. The mission demonstrates NASA’s progress toward deep‑space crewed flights beyond low‑Earth orbit. By contrast, the most distant human‑made...
Adolescent Disordered Eating and Epigenetic Age Acceleration
A new longitudinal analysis of the Australian Raine Study examined whether adolescent disordered eating predicts epigenetic age acceleration (EAA). Using DNA‑methylation data from 797 participants at ages 14 and 17, the researchers found that restrictive eating behaviors at 14 were...
Neural Sequences Underlying Directed Turning in Caenorhabditis Elegans
Researchers uncovered a novel error‑correcting turning strategy in Caenorhabditis elegans, showing that worms adjust the angle of each reorientation to improve their bearing in odor gradients. Using whole‑brain calcium imaging of freely moving animals, they mapped a stereotyped sequence of...
Analysis of Rare Coding Variants in Schizophrenia-Associated Genes and Generalised Cognition in the UK Biobank
The study examined whole‑exome data from 396,848 UK Biobank participants to test whether rare damaging coding variants in schizophrenia‑linked genes affect generalised cognitive ability (g) in individuals without psychiatric diagnoses. Rare protein‑truncating variants (PTVs) and deleterious missense mutations in loss‑of‑function...
AI-Designed Proteins Built From Scratch Can Recognize Specific Compounds
Researchers at KAIST, led by Gyu Rie Lee and David Baker, used an AI model to design artificial proteins from scratch that selectively bind specific compounds. The team experimentally validated six de novo binding proteins, including a cortisol‑responsive biosensor that functions as a chemical‑induced...
Survival of the Wittiest
Linguist Ljiljana Progovac proposes that early verb‑noun compounds such as "killjoy" were the first forms of verbal wit, giving our ancestors a non‑violent way to compete and cooperate. Brain imaging shows these compounds trigger heightened activity in the fusiform gyrus,...
Antarctic Fur Seals Now Endangered as Climate Change Reduces Krill for Pups
The IUCN Red List has reclassified the Antarctic fur seal (Arctocephalus gazella) from “least concern” to “endangered,” citing a 50% population decline over the past 25 years. Numbers dropped from roughly 2.2 million adults in 1999 to about 944 000 in 2025,...
Emperor Penguins Are Now Endangered Amid Climate Change and Melting Ice
The International Union for Conservation of Nature (IUCN) has upgraded the emperor penguin to endangered status, citing rapid sea‑ice loss across Antarctica. Recent satellite analyses reveal that nearly 10% of the species—about 24,000 mature birds—have died from habitat degradation between...
Colombian Night Monkeys: New Research Looks at These Primates, Little-Known Due to Their Nocturnal Nature
Colombian night monkeys (genus Aotus) have long evaded scientific scrutiny because their nocturnal habits make field observation difficult. Researchers like doctoral student Sebastián Montilla are now pioneering in‑situ studies in Colombia’s coffee‑growing regions, aiming to document behavior that has mostly...
Meeting Climate Targets Requires Humanity to Reorient Its Relationship With Nature, New Study Says
A new Frontiers in Science paper argues that meeting global climate targets requires a “Nature Positive” strategy that halts biodiversity loss by 2030 and embeds economies within Earth’s ecological limits. The authors, a mix of scientists, conservationists and Indigenous leaders,...
A New Memory Chip Survives 700°C and Could Enable AI in Space
Researchers at the University of Southern California have demonstrated a memristor memory chip that functions at 700 °C (1,300 °F) without degradation. The device uses a tungsten electrode, hafnium‑oxide insulator and a graphene interlayer that blocks tungsten filament formation. It retains data...