Abemaciclib May Be New Standard for Sarcoma Subtype
Abemaciclib dramatically extended progression‑free survival in a phase‑3 SARC041 trial for patients with advanced dedifferentiated liposarcoma, achieving a median PFS of 9.7 months versus 1.5 months on placebo. The study, the first positive phase‑3 effort in this sarcoma subtype, also showed a trend toward longer overall survival, though crossover diluted the signal. Safety was manageable, with hematologic toxicities comparable to its breast‑cancer use. These data position the CDK4‑selective inhibitor as a potential new standard of care for a disease with limited therapeutic options.
Oncolytics Biotech® Announces Positive Initial Preclinical Findings Supporting Further Evaluation of Pelareorep in Combination with RAS-Targeted Approaches
Oncolytics Biotech reported that its oncolytic virus pelareorep, when paired with RAS‑targeted inhibitors, produced markedly stronger anti‑tumor effects in a solid‑tumor preclinical model. The company will extend this work to pancreatic ductal adenocarcinoma and colorectal cancer, testing KRAS G12C, pan‑RAS and...
A Tiny Part of Your Brain May Still Listen Under Anesthesia
Scientists used high‑density Neuropixels probes to record hippocampal activity in seven patients undergoing surgery for epilepsy while they were under general anesthesia. More than 70% of the monitored neurons responded to auditory tones and could differentiate rare oddball sounds from...
Forever Chemicals May Change when They Enter Your Body. Here's What We Know.
Researchers are mapping how per‑ and polyfluoroalkyl substances (PFAS) – the so‑called forever chemicals – change once they enter the human body, creating a distinctive "fingerprint" in blood and tissue. The work reveals that many diverse PFAS compounds ultimately convert...
ASCO26: Verzenio Gives Hope of Liposarcoma Treatment Advance
An investigator‑initiated phase 3 SARCO41 trial showed Eli Lilly’s CDK4/6 inhibitor Verzenio (abemaciclib) significantly prolonged progression‑free survival in patients with advanced dedifferentiated liposarcoma, achieving a median PFS of 9.7 months versus 1.5 months on placebo. Overall survival also trended higher, with more than...
ASCO: Biopharma Has Pancreatic Cancer ‘Surrounded’ as Immuneering’s Drug Adds 9 Quality Months
Immuneering reported that its MEK inhibitor atebimetinib combined with modified gemcitabine/nab‑paclitaxel (mGnP) produced a 17.3‑month median overall survival in a Phase 2a trial of 55 first‑line metastatic pancreatic‑cancer patients, nearly doubling the 8.5‑month benchmark from the historic MPACT study. The regimen...
EU Research Project StoRIES: Roadmap for Hybrid Energy Storage Strengthens Europe's Energy Independence
The EU‑funded StoRIES project, coordinated by the Karlsruhe Institute of Technology, wrapped up after four years of work linking 250 research institutions across Europe. It produced a technology roadmap that promotes hybrid energy storage—combining batteries, thermal storage and hydrogen—to meet...
"You Get One Crop Failure and There Go Your Profits for the Year"
Bruce Bugbee, professor and Apogee Instruments CEO, presented a decades‑old model that translates incoming photon flux into a photon conversion efficacy (PCE) of one gram of edible biomass per mole of photons. The framework adjusts for carbon use efficiency and harvest...
Nanoengineered Materials Can Store and Release Hydrogen at Room Temperature
Researchers at Zhejiang and Fudan Universities have engineered a nanocomposite that couples ultrafine lithium borohydride (LiBH₄) particles with 3 nm nickel clusters, enabling hydrogen uptake at room temperature. The material leverages highly reactive B‑spike atoms and nickel‑catalyzed H₂ dissociation to regenerate...
The "Public" In Public Space Agency
Artemis 2 returned after a ten‑day lunar flyby, marking the farthest human travel since Apollo and capturing unprecedented public attention. The mission’s splashdown became a shared moment in living rooms, kitchens and group chats, drawing doctors, teachers and children into the...
What to Know About Rubisco, the Most Abundant Protein on Earth
Rubisco, the most abundant protein on Earth, is gaining attention as a sustainable protein source. Companies such as New Zealand‑based Leaft and U.S. firm Plantible are scaling extraction from alfalfa and duckweed to create consumer‑ready powders and drinks. While the...
The Forgotten Organ that Could Predict How Long You Live
Researchers at Mass General Brigham used AI to analyze CT scans of more than 27,500 adults and found that a healthier thymus—a small organ traditionally thought to shrink out of relevance after puberty—correlates with markedly lower mortality and disease risk....
Space Sector to Become Key Component of India's Overall Economy: Jitendra Singh
India’s space economy, now valued at roughly $8.5 billion, is projected to reach $40‑45 billion within the next ten years, according to Minister Jitendra Singur. The surge follows liberalisation measures that opened the sector to 100% foreign direct investment and created a single‑window...
Nova Graphene Advances Graphene-Enhanced Marine Coatings Through New ITB Collaboration with Salt Separation Services
Nova Graphene has entered an R&D partnership with UK‑based Salt Separation Services, supported by Memorial University testing, under Canada’s Industrial and Technological Benefits (ITB) program and in collaboration with Seaspan Shipyards. The joint effort will advance Nova’s CarbonEra™ graphene‑enhanced marine...
Scientists Are Racing to Stop a Type of Ebola We Have No Vaccine For
The Democratic Republic of the Congo and neighboring Uganda are facing an outbreak of the Bundibugyo strain of Ebola, a virus for which no approved vaccine or targeted treatment exists. The World Health Organization declared the situation a public‑health emergency...
There Are About 20 Quadrillion Ants Alive on Earth at Any Moment — Enough that Their Combined Biomass Outweighs Every...
Researchers from the University of Hong Kong and Würzburg published a PNAS study estimating that roughly 20 quadrillion ants inhabit Earth at any moment, translating to about 2.5 million ants per person. Their analysis puts global ant biomass at 12 megatonnes of...
China Has Approved the World’s First Invasive Brain-Computer Chip—Here’s What’s Next
Chinese startup Neuracle’s NEO invasive brain‑computer interface received the world’s first regulatory approval for commercial use, allowing patients with spinal‑cord paralysis to regain hand function. The coin‑size device, placed on the dura mater, enabled patient Dong Hui to write and...
Student Astronomer Discovers 'Rosetta Stone' For Mysterious Cosmic Signals
An international team led by University of Sydney astronomers has identified the white dwarf binary ASKAP J1745‑5051 as the source of long‑period radio transients, a class of mysterious cosmic pulses previously without a confirmed origin. Using CSIRO’s ASKAP radio telescope, they...
Study Suggests Sweetener May Contribute to Liver Disease
A study from Washington University in St. Louis reveals that sorbitol, a common low‑calorie sweetener, can be converted into fructose in the liver when gut bacteria that normally break it down are absent or overwhelmed. Using zebrafish models, researchers showed...
Parent-Rated Improvement Is Not Enough to Establish Clinical Scalability
A multicentre, sham‑controlled trial examined accelerated continuous theta burst stimulation (a‑cTBS) targeting the left primary motor cortex in children with autism spectrum disorder, including many with co‑occurring intellectual disability. The study reported modest improvements on the caregiver‑rated Social Responsiveness Scale...
MiR-146a Is a Pleiotropic Regulator of Motor Neuron Degeneration
Researchers profiled motor‑neuron microRNAs in the SOD1^G93A mouse model of amyotrophic lateral sclerosis and identified miR‑146a as a key regulator. Deleting miR‑146a prolonged survival and reduced spinal gliosis, especially in heterozygous knockouts, though motor‑neuron loss remained unchanged. Paradoxically, aged miR‑146a‑null...
Causal Interplay Between Lactose Intolerance and Gut Microbiota: A Combined Bidirectional Mendelian Randomization and in Vivo Validation Study
A bidirectional Mendelian randomization study combined with a lactose‑intolerant rat model uncovers causal links between gut microbiota and lactose intolerance (LI). The analysis identifies Deltaproteobacteria and Bilophila as risk‑enhancing taxa, while Paraprevotella and Blautia appear protective. Reverse MR suggests that...
Vitamin D Status and Helicobacter Pylori Infection: Clinical Associations and Lipid Pathway Differences in an Exploratory Metabolomics Sub-Study
A cross‑sectional study of 502 Lebanese adults found vitamin D deficiency strongly associated with Helicobacter pylori infection, with deficiency conferring roughly 98 % higher odds compared with sufficient levels. Multivariable analysis showed that both insufficiency and normal vitamin D status reduced infection odds by...
Desperate to Fight Ebola Outbreak, Congo Weighs Using Longshot Vaccine Options
The Democratic Republic of the Congo is battling a fast‑spreading Bundibugyo Ebola outbreak that has produced 291 confirmed cases and 43 deaths in two weeks. With no licensed vaccine for the rare BDBV strain, health officials are debating the emergency...
Wockhardt Marks Research Milestone with USFDA Approval for Novel Antibiotic Zaynich
Wockhardt has secured US FDA approval for Zaynich, an intravenous antibiotic combining cefepime and zidebactam, to treat complicated urinary tract infections in adults. The drug earned Qualified Infectious Disease Product and Fast Track designations and follows recent clearance by India’s...
New Imaging Method Distinguishes Inflammation From Lung Fibrosis
A new SPECT/CT imaging technique using the tracer 99mTc‑maraciclatide can reliably differentiate inflammation from fibrosis in patients with interstitial lung disease (ILD). In a pilot study of 15 participants—including idiopathic pulmonary fibrosis, fibrotic hypersensitivity pneumonitis, and healthy controls—the method showed...
University of Cincinnati Opens New Research Facility Aimed at Advancing MRI Innovation
The University of Cincinnati, together with GE HealthCare, UC Health, Cincinnati Children’s Hospital and JobsOhio, opened the Imaging Research & Development Center on its medical campus. The facility houses a state‑of‑the‑art 3‑tesla wide‑bore MRI scanner that will support AI‑enhanced imaging...
Controversial Gene Therapy for Alzheimer’s Disease
Advanced Science News highlighted three breakthrough biotech applications. An AI‑powered wearable headband uses a brain‑computer interface and mindfulness cues to alleviate car sickness, reporting up to 60% symptom reduction. Researchers demonstrated vitrification techniques that preserve Anopheles gambiae mosquito larvae for...
Biodegradable Brain Probes Eliminate the Need for Risky Surgical Removal
A new AI‑driven wearable headband that combines motion sensing with mindfulness techniques has shown up to a 40% reduction in car‑sickness symptoms during pilot trials. Researchers have issued a call for a standardized testing framework for triboelectric nanogenerators (TENGs) to...
India Achieves AI Breakthrough in Cancer Care with Mask-Free, Simulationless Radiotherapy
Sir HN Reliance Foundation Hospital in India successfully treated a head‑and‑neck cancer patient using a mask‑free, simulation‑less radiotherapy protocol that combines Surface Guided Radiotherapy (SGRT) and adaptive radiotherapy. The approach eliminated the need for immobilisation masks and simulation CT scans,...
Sweden’s Esrange Space Center Launches Suborbital Rocket
On 28 May SSC Space launched SubOrbital Express‑5 from Sweden’s Esrange Space Center, marking the 17th MASER rocket mission since 1987. The flight delivered twelve scientific experiments from nine countries, using four modules that studied metals, medical fluids, blood behavior, and...
Intense Heat During Mecca’s Spring Threatens Millions of Hajj Pilgrims
A World Weather Attribution report warns that rising temperatures are shrinking the safe window for the Hajj pilgrimage in Mecca. Average May temperatures have risen about 3.5 °C since pre‑industrial times, pushing peak heat into the 40 °C range every two to...
Daily Pill Doubles Survival Time for Pancreatic Cancer Patients
A phase III trial of the oral KRAS inhibitor daraxonrasib showed median overall survival of 13.2 months for advanced pancreatic cancer patients, roughly double the 6.6 months achieved with standard chemotherapy. The study enrolled 500 participants across North America, Europe...
Something Made Earth's Molten Core Reverse Direction In 2010
In 2010, satellite measurements of Earth’s magnetic field revealed a localized eastward flow reversal in the outer core beneath the Pacific Ocean, contradicting the planet’s usual westward convection. The anomaly appeared as a wave‑like structure, suggesting a bulk shift in...
Biopolymer-Based Hydrogel Formulations for Improved Seed Coating Performance
Researchers at Nazarbayev University have created biodegradable hydrogels from starch and carboxymethyl cellulose that can absorb up to 17.5 g of water per gram and degrade about 67 % in soil. When applied as seed coatings, the formulations doubled sugar beet seedling...
In a First, This Animal Hijacks the Power of Bioluminescence From Its Victims
Researchers at Tohoku University sequenced the genome of the golden sweeper fish (Parapriacanthus ransonneti) and confirmed it lacks the luciferase gene needed for bioluminescence. Instead, the 7‑cm fish sequesters fully formed luciferase protein from its luminous ostracod prey, Vargula hilgendorfii,...
Passive Heart-Rate Monitoring During Smartphone Use in Everyday Life
Researchers unveiled a smartphone‑based deep‑learning system, PHRM, that passively measures heart rate and daily resting heart rate during routine phone use. The platform was validated on over 162,000 videos from diverse participants, meeting industry accuracy standards with mean absolute percentage...
Hydrophobic Liquid Electrolyte Interphases for Efficient Aqueous Zinc Batteries
Researchers introduced a 1.8 mol % ether‑based additive, 1,2‑diethoxyethane (DEE), that self‑assembles into a hydrophobic liquid electrolyte interphase (LEI) on zinc electrodes. The LEI repels water, expanding the electrochemical stability window of aqueous zinc batteries to 3.08 V while preserving high ionic conductivity...
How Long Can Humans Live? We Simply Don’t Know
Longevity researcher Saul Newman argues that most claims of extreme human age are built on unreliable paperwork. He shows that pension fraud, clerical mistakes, and identity swaps inflate supercentenarian counts, especially in countries with weak birth‑registration systems. Statistical analyses reveal...
Enantioselective Hydrogen Atom Relay via Non-Covalent Catalyst Assembly
Researchers at EPFL have introduced a new method to generate chiral hydrogen atom transfer (HAT) catalysts through non‑covalent self‑assembly of chiral phosphoric acids with commercial 2‑mercaptopyridines. The assembled catalyst acts as a single chiral entity that both abstracts and delivers...
Intracellular Neuronal Recordings Across DNA Tiles
Researchers engineered DNA tiles that spontaneously embed into live neuronal membranes, forming nanometer‑scale ion channels with a measured conductance of about 3 nS and pore resistance near 500 MΩ. The tiles enable stable, repeatable intracellular‑like recordings and allow targeted delivery of small...
Towards a Holistic Understanding of Pain in the Biomarker Age
A new perspective paper in Nature Neuroscience argues that pain biomarkers, while unable to prove subjective experience, can still play a valuable role when embedded in a bio‑psycho‑social framework. The author emphasizes epistemic humility, ethical safeguards, and interdisciplinary collaboration to...
Why Pain Biomarkers Cannot Replace the Patient Experience
In a commentary published in Nature Neuroscience, a multinational team of pain researchers argues that neuroimaging biomarkers cannot supplant patients’ self‑reported pain ratings. While brain‑based measures illuminate pain pathways, the authors stress that the subjective experience remains the only reliable...
Telespazio Repurpose Geostationary-Focused Dish For Bouncing Radio Signals Off The Moon
On 29 May 2026 Telespazio completed an Earth‑Moon‑Earth (EME) moon‑bounce test using its 32‑meter LARIO 1 antenna, normally aimed at geostationary satellites. The 5 GHz signal was transmitted, reflected off the Moon’s surface and received by a 2.4‑meter dish, proving the dish can track...
Checks Reveal Young Women with Deadly 'Silent' Heart Risk
A voluntary UK screening program examined nearly 40,000 women aged 14‑35 and identified 175 with previously undiagnosed heart conditions, including 94 at high risk of sudden cardiac death (SCD). The study also revealed that standard ECG checks missed 92 abnormalities,...
This Blood-Sucking Fly Drastically Transforms When It Finds Its Prey
A new study in the Journal of Experimental Biology shows that deer keds dramatically reduce expression of vision‑related genes after they locate a host. Researchers collected winged keds and host‑bound keds in Tuscany, sequenced brain RNA, and found opsin gene...
A Natural Chemistry Laboratory in Protostar Shock Waves
Astronomers using NOEMA have identified three complex organic molecules—acetonitrile, acetaldehyde and deuterated methanol—in the shock‑driven outflow of the Class 0 protostar IRAS 4B1 in NGC 1333. The detections mark the first secure observation of these COMs in a protostellar jet, highlighting shock fronts...
Sarawak Builds Local Satellite Technology and AI Capabilities
Sarawak’s state government is launching a multi‑year push to develop homegrown aerospace, satellite engineering and artificial‑intelligence capabilities. The plan includes a CubeSat nano‑satellite slated for launch by 2030 to provide geolocation, forestry monitoring and disaster‑management services. A 405‑hectare AI Data...
First Comprehensive Look at Breast Cancer in Native American Women Reveals Key Genetic Differences
Researchers at the University of Notre Dame published the first detailed genetic analysis of breast cancer in Native American women, comparing 17 tumor samples with nearly 700 white‑patient cases from The Cancer Genome Atlas. The study, appearing in npj Precision...
Dual PET Imaging Detects Tumor Progression and Heart Inflammation During Cancer Treatment
Researchers unveiled a dual PET imaging method that simultaneously visualizes tumor growth and cardiac inflammation using a CCR2‑targeted radiotracer, 64Cu‑DOTA‑ECL1i. In mouse models, checkpoint inhibitor therapy slowed tumors but heightened cardiac CCR2 signals, while adding the JAK1 inhibitor itacitinib improved...