
High‑altitude hypoxia curbs blood‑sugar spikes in mice
A mouse study found that low‑oxygen (hypoxic) conditions cause red blood cells to absorb far more glucose and convert it into a molecule that eases oxygen release, acting as a glucose sink. Mice exposed to 8% oxygen showed markedly smaller blood‑sugar spikes after glucose injections, and the effect persisted after they returned to normal air.

Kodiak Sciences announced that its experimental eye drug Zenkuda (tarcocimab tedromer) achieved positive topline results in the GLow2 Phase 3 trial for diabetic retinopathy, outperforming sham treatment. The study met its primary endpoint, delivering a statistically significant gain in visual acuity and a favorable safety profile. This marks the first late‑stage validation of a non‑VEGF‑targeted approach in the disease. The news arrived alongside other pipeline updates from Astellas and Anavex, underscoring a busy week for ophthalmic biotech.

A new interdisciplinary study explains how Pele’s hair, the ultra‑thin volcanic glass strands named after the Hawaiian fire goddess, forms when bubbly magma is stretched by high‑velocity gas jets. Researchers observed strands up to two feet long that can be...

Ten Johns Hopkins University researchers have been elected to the 2025 class of American Association for the Advancement of Science (AAAS) Fellows, joining 449 distinguished scholars across 24 scientific disciplines. The fellows—spanning physics, biological sciences, medical sciences, and engineering—will be...

Researchers at Israel's Volcani Center used CRISPR/Cas9 to inactivate the 1,2RhaT gene in Citrus paradisi, effectively halting production of bitter compounds such as naringin, neohesperidin, and poncirin in leaf tissue. The gene edit eliminates the bitter taste pathway, and the...

Denmark’s LUNA consortium—Aalborg University, Pri‑Dana Elektronik and GomSpace—has launched a three‑year effort to create low‑loss, multiband nanosatellite antennas with mechanical beam steering. Backed by Innovation Fund Denmark, the project receives roughly $3 million in funding, with GomSpace contributing about $1.1 million. The...

A recent Belgian study published in the Journal of Physiology examined exogenous ketone supplementation around training. Researchers found that consuming ketones during exercise did not improve performance metrics. However, taking ketone esters after a workout appeared to accelerate metabolic recovery...

OrbitsIQ Global announced the validation of its Enhanced Spread Spectrum Aloha (E‑SSA) waveform, co‑developed with Wrocław Tech and backed by ESA. The new protocol lets up to 500 devices share a single 4 MHz channel, processing roughly 30,000 frames per second...

Researchers in Buenos Aires discovered that multidrug‑resistant bacteria from Argentine hospitals are also highly resistant to glyphosate, a widely used herbicide. Comparative testing showed similar resistance in environmental strains from the glyphosate‑free Paraná Delta, suggesting a genetic link via efflux‑pump...

As a medical school professor, I've spent decades writing papers and reviewing studies. Now AI can do it all -- start to finish. Researchers from Sakana AI, Oxford, and UBC just published in Nature: "The AI Scientist" -- a system that...

Dr. Emanuela Offidani, Tris Pharma’s Medical Director of Digital Health Strategy, highlighted that ADHD is increasingly recognized as a lifelong condition that often goes undiagnosed in women because symptoms are less overt. She explained that Tris Pharma’s proprietary LiquiXR delivery...

I have a story today about the quest to turn eggs into low-cost factories for medicines. Gift link: https://nyti.ms/4bzSabB

XRISM’s Resolve spectrometer has measured the hot core of starburst galaxy M82, revealing gas at ~20 million K and a velocity dispersion of about 595 km s⁻¹. These conditions correspond to a mass outflow of roughly seven solar masses per year and an energy...
A joint study by the American Psychological Association, Harvard Health Publishing and the National Institute on Aging released data showing an unprecedented stress surge among women aged 35‑54. The findings link chronic pressure to fatigue, anxiety, sleep problems and heightened...
NASA announced a new catalogue of 45 rocky exoplanets that lie within their stars' habitable zones. Compiled by Professor Lisa Kaltenegger's team, the list is intended to focus upcoming observations with JWST and the Roman Space Telescope on the most...
Corcept Therapeutics saw its shares climb almost 20% after the U.S. FDA approved its lead drug Lifyorli in combination with nab‑paclitaxel for platinum‑resistant ovarian, fallopian tube and primary peritoneal cancer. The approval, based on a 381‑patient trial, validates the company's...

Johns Hopkins scientists have assembled the most detailed cellular atlas of the human neocortex, merging data from nearly 200 studies and over 30 million cells. The open‑access web portal makes the high‑resolution map available to researchers worldwide, facilitating exploration of gene‑expression...

Today we're introducing TRIBE v2 (Trimodal Brain Encoder), a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings...

Interlune, a lunar‑resource startup, announced that its first customers are ready to purchase helium‑3 extracted from the Moon. Helium‑3 is touted as a fuel for next‑generation nuclear fusion reactors that produce no long‑lived radioactive waste. The company highlights the technical...
The Canadian Centre for Electron Microscopy (CCEM) has been awarded a $15.5 million grant from the Canada Foundation for Innovation. The funding will expand national nano‑characterisation capabilities, linking atomic‑scale insights to Canada’s critical‑minerals strategy, semiconductor supply chain and electronic‑waste recycling efforts.

In 1997 NOAA’s hydrophone network captured an ultra‑low‑frequency, extremely loud underwater sound dubbed the “Bloop,” heard across sensors spaced over 3,000 miles. Initial speculation ranged from a giant sea creature to shifting ice, but acoustic analysis later matched the signature...

Scientists at Vrije Universiteit Brussel discovered that the acidic environment of sourdough activates wheat enzymes, breaking down arabinoxylan fibers. The conversion turns water‑extractable arabinoxylans into water‑unextractable forms, altering dough texture and digestibility. Specific bacteria, such as Lactococcus lactis and Limosilactobacillus...
Precigen (PGEN) reported fiscal Q4 2025 revenue of $9.7 million, up 149% year‑over‑year, and projected first‑quarter 2026 sales to exceed $18 million. The surge stems from the rapid commercial rollout of its FDA‑approved gene‑therapy Papzimius and broader payer coverage across the United...
Biotech start‑up Neion Bio is pioneering a method to turn chicken embryos into miniature drug factories. Scientists micro‑inject genetic constructs into three‑day‑old embryos, reprogramming the developing bird to synthesize pharmaceutical compounds within the egg. The approach promises faster, cheaper production...

In June 2013 a coordinated occultation campaign across South America captured the centaur Chariklo passing in front of star UCAC4 248‑108672, revealing two brief dimming events that indicated the presence of rings. The finding, published in *Nature* and announced on March 26 2014,...

Researchers have identified a new giant DNA virus, ushikuvirus, isolated from a freshwater pond near Tokyo. The virus infects the amoeba Vermamoeba vermiformis and carries a full complement of eukaryote‑like histone genes. Unlike its relative medusavirus, ushikuvirus destroys the host...

Researchers at Nanjing University found that adding manure‑derived hydrochar or thermoplastic polyurethane microplastics to rice‑paddy soils significantly boosts labile phosphorus—by 21.1% and 14.2% respectively. Hydrochar supplies readily degradable carbon, spurring fast‑growing copiotrophic bacteria that rapidly solubilize phosphorus. In contrast, the...

As a medical school professor, I can tell you: the textbooks got this one wrong. We taught that once you have prostate cancer, exercise is nice but optional. New data says it may be the most powerful tool in your arsenal. 828...

IBM announced that its 127‑qubit quantum processor successfully simulated the magnetic properties of real‑world materials, achieving 99% fidelity compared with laboratory measurements. The experiment reproduced the behavior of iron oxide at room temperature, a benchmark previously out of reach for...

Researchers at the University of Western Ontario tested 13 photovoltaic modules, including semi‑transparent cadmium telluride (CdTe) and low‑transparency crystalline silicon (c‑Si), in field‑scale agrivoltaic trials with turnips. The 60 % transparent CdTe panel delivered the highest fresh root weight (176.5 g) and...

Researchers are investigating vagus nerve stimulation (VNS) as a way to preserve the health of the locus coeruleus, a tiny brainstem region where tau protein first accumulates and predicts Alzheimer’s disease. The locus coeruleus produces norepinephrine, essential for sleep, attention,...

Union Minister Jyotiraditya Scindia told Parliament that India is accelerating toward global 6G leadership under Prime Minister Narendra Modi. The newly operational Anusandhan National Research Foundation (ANRF) will mobilise roughly $6 billion in funding through 2028, including a $1.7 billion central budget...
“These findings challenge the assumption that lifespan extension necessarily compresses morbidity, highlighting the need to consider lifespan, healthspan, and CoM as endpoints when evaluating anti-aging interventions. We do not claim that life-extending interventions categorically fail to achieve CoM; rather, we demonstrate...

NASA Administrator Jared Isaacman unveiled a new plan to transition from the International Space Station to Commercial LEO Destinations (CLDs) by adding a core module that can power and support up to two commercial segments before detaching. Lawmakers on the...

Agnikul Cosmos successfully hot‑fired its Agnite booster engine, a one‑metre, single‑piece Inconel rocket engine printed in just seven days. The monolithic design eliminates welding, machining and assembly, cutting manufacturing cost to roughly one‑tenth of conventional methods. The engine uses electric‑motor‑driven...

How does the menstrual cycle affect gastrointestinal symptoms during exercise? 🩸 This new study recruited 12 eumenorrheic females to complete 2 x 45-min bouts of a simulated football match on a treadmill ⚽️ Simulations were completed in… 1️⃣ Phase 1 (P1, days...
Parental age effects on offspring fitness in a wild population of a short-lived reptile G "adds to the growing literature suggesting that negative effects of parental age on offspring fitness may not be as prevalent as once thought, particularly in wild...

A recent Lithuanian Sports University study examined short‑term broccoli powder supplementation in 17 healthy men performing an incremental bike‑ergometer test. Participants consumed 10 g of broccoli powder (0.5 % mustard seed) for 14 days, which significantly increased urinary sulforaphane, confirming absorption. However,...

The rollout of the first Soyuz-5 rocket to launch pad Site 45 in Baikonur, Kazakhstan, was postponed from today to March 29, in turn, pushing its inaugural flight to April 2, at the earliest, according to Kazakh media. Context: https://t.co/DBcHRiQe36 https://t.co/S8p6AAE3IL
This week's Biotech Scorecard: Allogene $ALLO: A preview of its April interim analysis. Very interesting (to me, at least) There just might be a path forward for off-the-shelf CAR-T therapy in B-cell lymphoma. Frontline consolidation. Read all about it: https://t.co/tcPFelUH3C
Gene therapy isn't just targeting diseases anymore—it's targeting aging itself. The hallmarks of aging are becoming editable code. Longevity Escape Velocity isn't a fantasy. It's an engineering problem. And we're solving it.

Harvard’s twistable light chip could give drug developers a new tool for sorting mirror-image molecules https://t.co/WkjjD38exo https://t.co/5kr4d9f6sa

I almost sent a figure with wrong cluster labels to my collaborators. The R code ran perfectly. No errors, no warnings. I caught it because cluster 2 showed upregulated genes in RNAseq but reduced chromatin accessibility in ATACseq. Biologically, that's backwards....
Meager new emissions reduction plans from New Delhi limit the prospects of major progress through 2035 from the three biggest polluting nations https://t.co/H7X2IWuZRQ