
Artemis II crew prepares for historic lunar flyby
NASA’s Artemis II astronauts have passed the mission’s halfway point and are gearing up for a five‑hour lunar flyby on April 6, during which they will photograph the Moon’s far side. Orion has completed the trans‑lunar injection burn, placing the crew on a free‑return trajectory for the flyby.
South Korean researchers from Seoul National University and Chosun University published a paper showing no scientific link between genetically modified (GM) crops and chronic diseases, confirming earlier findings from the 2016 National Academies report. Their analysis of PubMed literature and epidemiological data across countries with and without GM cultivation found no increase in cancer, preterm birth, allergies, or other health issues. Despite this consensus, public skepticism remains high, driven by media amplification, social‑media echo chambers, and lingering concerns about glyphosate. The study underscores a persistent gap between scientific evidence and consumer perception.

Low-dose rapamycin alleviates clinical symptoms of fatigue and PEM in ME/CFS patients via improvement of autophagy: a pilot study Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem disorder characterized by profound fatigue… 👉 “Low-dose rapamycin effectively reduced PEM and other key...

Researchers mapped the transcriptomes of motor‑cortex neurons from roughly 80 post‑mortem brains and identified five excitatory neuron subgroups that are uniquely vulnerable to TDP‑43 protein aggregates in ALS and frontotemporal dementia. The study shows that TDP‑43 clumps disproportionately target excitatory...

Alzheimer’s is affecting younger adults, with an estimated 200,000 Americans aged 30‑64 diagnosed. A University of California‑San Francisco mouse study found that regular exercise triggers the liver to release the enzyme GPLD1, which clears the harmful protein TNAP and fortifies...

Researchers led by Matthew O’Connor have published a comprehensive review of 7‑ketocholesterol (7KC), an oxidized cholesterol formed by reactive oxygen species. The paper details how 7KC accumulates in atherosclerotic plaques, transforms macrophages into inflammatory foam cells, and exerts neurotoxic effects...
Platelet‑rich plasma (PRP) is increasingly used to accelerate healing of acute hamstring strains, a common cause of missed competition. A 2026 systematic review and meta‑analysis of six randomized controlled trials involving 277 athletes evaluated PRP’s impact on return‑to‑play (RTP). The...
The editorial challenges the long‑standing view that intervertebral discs inevitably degenerate, arguing that discs are mechano‑responsive tissues capable of structural and metabolic adaptation. It highlights how dynamic loading during physical activity facilitates nutrient exchange, counteracting the disc’s avascular nature. By...
A retrospective study of 388 female athletes shows that a dual‑energy X‑ray absorptiometry (DXA) derived % fat Z‑score predicts menstrual status more accurately than traditional BMI or percent expected body weight (% EBW). Using a cutoff of < −1.0, sensitivity for detecting amenorrhoea rose...
The CONCUSS randomized trial compared immediate versus delayed office‑based vergence/accommodative therapy with movement (OBVAM) for concussion‑related convergence insufficiency in patients aged 11‑25. After six weeks, 88% of the immediate group achieved success on near point of convergence and positive fusional...
Propanc Biopharma announced that its proenzyme therapy PRP is moving toward a Phase Ib first‑in‑human study for advanced pancreatic cancer. The company highlighted preclinical data showing more than 85 % tumor‑growth inhibition and secured FDA orphan‑drug designation. A validated pharmacokinetic assay developed...

Researchers in the VIVID trial, one of the largest randomized studies on vitamin D and COVID‑19, found that a high‑dose vitamin D3 regimen (3,200 IU/day after a loading dose) did not lower acute disease severity, hospitalizations, or death. However, among participants...
AI is starting to expand the frontier of theoretical physics. Researchers are now using AI not just as a computational tool, but as something closer to a collaborator helping uncover patterns, generate hypotheses and explore mathematical landscapes that were previously impossible...

A 96‑centimetre tibia from New Mexico's Kirtland Formation has been re‑examined and identified as a massive tyrannosaurid, potentially predating the classic T. rex by several million years. The bone’s dimensions imply a 4.5‑tonne animal, larger than earlier North American tyrannosaurids but...
When you're pregnant, your baby is floating in its own pee. Sort of. By the third trimester, the majority of amniotic fluid comes from fetal urine. The baby swallows it, their kidneys filter it, and they pee it back out....

Scientists at the University of Padova synthesized fluorinated psilocin derivatives, identifying compound 4e as a lead that retains serotonergic activity while markedly reducing hallucinogenic effects in mice. In vitro assays showed 4e is a selective partial agonist at 5‑HT2A and...
Researchers at China’s Shenyang Institute of Automation have created magnetically controlled microrobots from diatom frustules for glioblastoma photodynamic therapy. The robots retain natural chlorophyll, serving as a built‑in photosensitizer, and can be steered via external magnetic fields to tumor sites....

The Stanley Family Foundation has renewed its support for the Stanley Center for Psychiatric Research at the Broad Institute, bringing its cumulative investment to over $1 billion, including a fresh $280 million pledge. The funding fuels large‑scale genetic studies aimed at uncovering...

Researchers have identified a streamlined DNA construct that could replace viral carriers in gene‑therapy applications. The study demonstrates that this minimalist DNA format delivers therapeutic genes with efficiency comparable to adeno‑associated viruses while eliciting a weaker immune response. Production of...
South Dakota Mines scientists led the first measurement of neutrino‑induced kaon production on an argon target, using three years of MicroBooNE data. The analysis identified eight kaon candidates from just ten potential events, providing the inaugural empirical cross‑section for this...

A recent study demonstrates that sending a shock wave through a magnetized plasma triggers the Richtmyer‑Meshkov instability, which manifests as mixed Kelvin‑Helmholtz roll‑ups and Rayleigh‑Taylor‑like plumes. Researchers used a two‑fluid model—separating ion and electron fluids—to capture these structures, which are...

Industry experts highlight three intersecting forces reshaping emerging biotech: the persistent funding and regulatory hurdles faced by early‑stage startups, the rapid migration of AI from a supportive tool to an operational backbone, and breakthrough computational methods—including quantum chemistry—that are redefining...
Imec announced a European university consortium of 26 institutions to develop CMOS 2.0, a post‑CMOS scaling paradigm that leverages fine‑grain wafer stacking and heterogeneous integration. The partnership will fund 26 PhD researchers who will remain at their home universities while accessing...

NASA recorded “the sound” of the Sun in space and it’s actually freaky… #space #astronomy #nasa #physics #astrokobi
RFK Jr is trying to get 14 peptides, without data on safety or efficacy, licensed and approved by FDA. His favorite is BPC-157. "Only three small human studies of BPC-157 exist, for instance, the largest of which is a telephone...

Swift Solar, a California start‑up, is buying key assets and patents from the bankrupt Meyer Burger to launch a production line for perovskite‑silicon tandem solar cells. The company claims its hybrid cells could reach 45 percent efficiency, far above the 30 percent ceiling...

New research reveals Brazil’s cerrado savanna stores roughly 1,300 tons of carbon per hectare in peat‑rich wetlands—about six times more than the Amazon’s above‑ground biomass. The peat formed over millennia under water‑logged conditions, sustained by groundwater that keeps the soil...

Researchers discovered that the Agouti gene acts as a molecular switch governing paternal behavior in African striped mice. Males housed together displayed aggression toward pups, while solitary males became attentive fathers, a shift linked to reduced Agouti activity in the...
Baseimmune announced a new fibrosis‑focused pipeline leveraging its computational protein design platform to create multi‑pathway immunotherapies, starting with idiopathic pulmonary fibrosis (IPF). The company aims to deliver proof‑of‑concept efficacy data for its lead IPF program in 2026‑2027, addressing the limitations...

Speaking at and attending @DellTech Symposium in Washington DC. The day kicked off with @MichaelDell, Dario Gil @ScienceUnderSec and Dell Federal VP @Surid. They’re framing how Dell and the U.S. Department of Energy aim to use AI, high‑performance computing, and...
The article critiques Nick Bostrom’s “cosmic host” hypothesis, which posits that the preferences of advanced civilizations or superintelligent AIs could become universal norms that humanity and its own ASI should follow. It dissects Bostrom’s six‑rung assumption ladder, outlines three possible...

Researchers at Johns Hopkins University examined how four psychoactive pharmaceuticals behave in tomatoes, carrots and lettuce irrigated with treated wastewater. In controlled experiments, the drugs and their metabolites accumulated predominantly in leaf tissue, with tomato leaves showing concentrations over 200...

A meta‑analysis of six randomized trials involving 5,924 stable CAD patients with atrial fibrillation found that oral anticoagulant (OAC) monotherapy reduced cardiovascular mortality by 31% and major bleeding by 54% compared with OAC plus a single antiplatelet. The benefit persisted...
Snakebite envenoming kills over 125,000 people each year and leaves three times as many disabled, while current horse‑derived antivenoms trigger severe allergic reactions in nearly half of patients. The high cost—up to $100,000 per course—and limited hospital access leave rural...
BridgeBio Pharma reported that its small‑molecule candidate BBP‑418 produced a 1.8‑fold increase in the α‑dystroglycan biomarker in a Phase 3 FORTIFY trial for limb‑girdle muscular dystrophy type 2I/R9, with effects sustained through 12 months. The trial enrolled 81 patients and also showed...
When Andrew Huberman asked about the root cause of aging, Dr. David Sinclair gave a surprisingly simple answer: "Aging is a loss of information in the same way you try to copy a cassette tape, or even if you send information...
The Firefly Alpha launch appears to have been fully successful. The LM-400 test satellite is being tracked in a 401 x 405 km x 123.0 deg orbit, and the Alpha second stage made a perigee lowering burn at about...

Researchers at Empa have created a stretchable polymer electrolyte based on modified silicone that conducts ions while retaining elasticity. The flexible electrolyte can suppress lithium dendrite growth and fill microscopic voids, enhancing solid‑state battery stability and energy density. Its ultra‑thin...
A quirk of relativity is the closest thing to achieving immortality Even relativity, with all the power of time dilation, won't increase the span of your lived life. But it can take you far into the future, and even to the ends...

What is the significance of microbes in tumors, a field mired in controversy? https://t.co/D5sHkLLsrT https://t.co/ntGLlke4iC

Aplagon Therapeutics has administered the first dose of its intravenous APAC candidate to a patient in a Phase 2a (HEALING) trial for peripheral arterial occlusive disease leading to chronic limb‑threatening ischemia in Finland. The study will enroll approximately 42 CLTI...

El Nino is coming in 2026. U.S. forecasters see El Nino arriving mid-year, placing 80%+ odds that it will be in place at the end of 2026. No other March forecast back to at least 2002 showed this strong of chances...
I guess the earth didn’t stop warming in the last 18 months. Sierra ski season over?
Jacobs and colleagues present a state‑of‑the‑art review of psilocybin and MDMA‑assisted therapies, highlighting their potential for treatment‑resistant depression and PTSD. The authors emphasize the distinct, session‑based paradigm that leverages acute neurobiological changes to produce lasting clinical benefits. However, they also...
psychedelics appear to facilitate the adoption or maintenance of physical activity habits, increase psychological flexibility, emotional resilience to acute stress, exercise and psychedelics have numerous potential complementary mechanisms https://t.co/gl4YK8bqaE

We know the microbiome plays an important role in health. Probiotics may play a role in the microbiome, but are they really as positive as they seem? This blog explores the potential of probiotics. Read now: https://t.co/EEXKgILfH7 https://t.co/5lwReH5Q2a
8 Resources to study Transcription factor binding, enhancers and histone modification distribution 1. ENCODE https://t.co/N5hScyoAoP
Tropic, a British gene-editing startup, has raised $105 million in new financing to expand production of bananas that don’t brown https://t.co/rHHAMO6mST
Cape Town and other areas of South Africa’s Western Cape Province saw record temperatures for March as a heat wave sears a region that’s vulnerable to both drought and wildfires https://t.co/C08EOcQMjw
US forecasters say an El Niño is favored to emerge in the Pacific Ocean by September, threatening to drive global temperatures higher and disrupt crops in the months ahead https://t.co/dk8PhPCFMQ
This does get to the question of what is a “lunar base”. Is one CLPS lander the first element of a lunar base? Two, near each other? Do they have to survive the lunar night??