The study applied UHPLC‑Q‑TOF‑MS/MS to profile resin glycosides (RGs) in leaves of nine sweet‑potato cultivars, identifying 128 distinct RGs. Multivariate analysis linked four pentasaccharide RGs—featuring 2‑methylbutyric and dodecanoic acid side chains—to potent pancreatic lipase inhibition. Xushu 32 and Blackheart extracts showed the highest Orlistat‑equivalent activity, while hydroponic cultivation of Beniazuma increased inhibitory RG content. The findings clarify structure‑activity relationships and highlight cultivar‑ and environment‑driven variation in anti‑obesity potential.
A retrospective matched cohort study of 2,482 dementia patients found that serum zinc deficiency (<70 µg/dL) was linked to a 54% higher risk of 1‑year all‑cause mortality. Deficient patients also experienced significantly increased rates of sepsis, ICU admission, urinary tract infection,...
The pilot study of 37 obese adults undergoing an eight‑week Very‑Low Energy Ketogenic Therapy (VLEKT) showed significant reductions in body weight, BMI, fat mass, fasting glucose, insulin, HOMA, triglycerides, LDL‑C, hepatic steatosis (CAP) and liver stiffness. Both the leptin‑to‑adiponectin ratio...
Researchers discovered that a population in Argentina's high‑altitude Andes carries a distinctive AS3MT gene variant that improves arsenic metabolism. The community has lived for millennia with groundwater containing arsenic levels up to 200 µg L⁻¹—far above WHO limits. DNA from 124 local...

Researchers engineered the heterotrophic microalga Prototheca moriformis to produce high levels of polymethylene octadecanoic acid (POA), achieving over 50% POA of total fatty acids and roughly 20.8 g/L POA in a 1 L fed‑batch fermentation. The study, funded by Nestlé and Checkerspot,...

Two randomized trials comparing conduction‑system pacing (CSP) with traditional biventricular (BiV) cardiac resynchronization therapy produced opposite results. The Chinese HeartSync‑LBBP study found that left‑bundle branch pacing reduced the composite of death or heart‑failure hospitalization and improved ventricular remodeling, while the...
SpaceX is set to launch its 30th Starlink batch of 2026, deploying 25 V2 Mini Optimized satellites on a Falcon 9 from Vandenberg Space Force Base. The mission, designated Starlink 17‑15, will lift off at 2:51:49 p.m. PDT and follow a southerly trajectory into...

A recent Evidation survey shows roughly one in seven U.S. adults on GLP‑1 drugs are microdosing, often to curb costs or chase longevity benefits without full‑dose side effects. Clinics like AgelessRx now market low‑dose regimens, while some physicians prescribe them...
Researchers engineered PdRu‑modified hierarchical In2O3 nanoflowers to create a gas sensor that rapidly detects trimethylamine (TMA), a key indicator of seafood spoilage. The 3D mesoporous architecture accelerates TMA diffusion, while the PdRu bimetallic surface enhances oxygen spillover, lowering activation energy...
Researchers have engineered a multifunctional hydrogel sensor by integrating a polyvinyl alcohol/silk fibroin double network with tannic‑acid‑coated liquid metal droplets, copper particles, and an ethanol post‑treatment. The resulting material exhibits a tensile strength of 1.452 MPa—483% higher than pure PVA—alongside 700%...
The researchers applied a density‑functional‑theory‑trained machine‑learning potential to map the silicon crystal‑melt interface and discovered a broad (>12 Å) transition region where structural, thermodynamic and dynamic properties evolve at different rates. A sharp change in the local order parameter \(\bar q_6\)...

California condors reintroduced by the Yurok Tribe appear to have laid their first egg in the Pacific Northwest, nesting in an old‑growth redwood after more than a century without breeding in the region. The pair, both nearly seven years old,...

The article outlines how space exploration is a sprawling scientific ecosystem rather than a single discipline, linking physics, geology, biology, engineering, law, economics, and more. It traces the evolution from Apollo’s multidisciplinary sample analysis to modern missions like Artemis and...

NASA announced on March 16 that it still has not re‑established contact with the MAVEN orbiter, which went silent after emerging from Mars’ far side on Dec. 6, 2025. The agency has resumed Deep Space Network attempts following a solar conjunction,...

The UK Health Security Agency reported that the meningitis outbreak in Kent appears to have peaked, with only two new cases reported on Friday. To date, 18 confirmed and 11 probable cases have been recorded, totaling 29 infections, of which...
Researchers have engineered a tri‑specific scaffold cell (TriSC) platform in the probiotic strain *Escherichia coli* Nissle 1917 that uses three orthogonal coiled‑coil motifs to create a programmable, reversible surface. The system enables simultaneous, selective attachment of multiple nanobody cargos and...
Researchers examined ball python scales and found dense arrays of 9 µm spikes that dramatically curb bacterial adhesion. In laboratory tests, the spiked skin reduced Escherichia coli and Staphylococcus aureus biofilm formation by 88% and 78% respectively, compared with standard polystyrene....
Researchers at the Australian National University examined two 2,000‑year‑old molars from northern Vietnam. Using non‑invasive SEM‑EDS analysis they identified iron and sulfur residues, indicating that ancient peoples mixed iron salts with tannin‑rich botanicals to blacken teeth. A modern animal tooth...

Researchers have designed a silicon metasurface that uses circular polarization as a cryptographic key, enabling two distinct holographic images to be stored in a single nanostructured layer. By applying an improved Gerchberg–Saxton algorithm and FDTD simulations, they mapped phase information...
Researchers from the University of Strasbourg and Macquarie University introduced an entanglement‑enhanced quantum‑sensing protocol that manipulates spin ensembles inside an optical cavity using tailored global drive pulses. By generating symmetric Dicke states, the scheme achieves near‑Heisenberg‑limited precision even when realistic...

LinusBio has broadened its ClearStrand‑ASD hair‑based screening to children up to ten years old, extending beyond the original under‑48‑month validation. The test analyzes a single strand of hair with proprietary robotics and laser technology to detect metabolic patterns linked to...

Researchers at the Ranger Uranium Mine applied native Eucalyptus‑derived litter to waste‑rock based soils during the wet season, spreading it 5 cm deep across 20 m × 20 m plots. After 15 weeks the inoculated soils showed higher microbial diversity, a shift toward decomposer taxa, and...
Researchers at Fudan University identified a specific subset of sympathetic Pdyn⁺ neurons that transmit psychological stress signals from the brain to the skin, triggering eosinophil‑driven inflammation in atopic dermatitis. The finding, published in Science, was supported by a retrospective analysis...
China has begun commercial production of Shoucell, a next‑generation regenerated cellulose fiber aimed at reducing textile pollution. The fiber employs a closed‑loop process that lowers water consumption and chemical waste compared with traditional viscose. Shoucell’s launch dovetails with Beijing’s green...
Researchers at University College London used Mendelian randomization on UK Biobank data (up to 341,326 adults) and found that greater muscle strength, measured by grip strength adjusted for body weight, causally reduces risk of depression and several core symptoms, especially...

The European Space Agency and the Chinese Academy of Sciences will launch the Smile mission on a Vega‑C rocket from French Guiana on Thursday 9 April at 08:29 CEST. The spacecraft will perform the first X‑ray imaging of Earth’s magnetic field and monitor...
Researchers from USC’s CLEAN Waters project report that, a year after the 2025 Palisades and Eaton fires, lead and other heavy metals in Los Angeles coastal waters and sand remain well below EPA and California safety limits. Initial spikes recorded...
Shionogi announced the first patient enrollment in its global Phase II Esprit trial, evaluating the oral substrate‑reduction therapy S‑606001 in adults with late‑onset Pompe disease. The 52‑week, double‑blind, placebo‑controlled study will run across the EU, the UK and the United States,...
Researchers have identified a new spider species in Ecuador’s Amazon that mimics the appearance of the parasitic fungus Gibellula, a relative of the cordyceps made famous by “The Last of Us.” The spider, belonging to the rarely seen genus Taczanowskia,...

Psychedelic research has surged, but recent psilocybin trials reveal modest benefits that fail to outpace placebo. A German study with 144 treatment‑resistant depression patients found no statistically significant advantage for high‑dose psilocybin. An open‑label review of 24 trials concluded psychedelics...
An estimated 7‑ton meteoroid exploded over Ohio on March 17, producing a bright fireball and a sonic boom heard across the Midwest. The rock, roughly 6 feet in diameter, fragmented on impact, scattering black, fusion‑crusted pieces that residents and professional meteorite...
Researchers have created a volatile memristor using the natural superlattice 2D material BiTiS3, which exploits interlayer coupling and sulfur‑vacancy‑induced lattice distortions to lower ion migration barriers. The device switches at low voltage within nanoseconds, as visualized by in‑situ conductive atomic...
The study introduces a bioinspired multifunctional flexible sensor (BMF) that mimics ant, spider, mosquito and lotus leaf structures. Built from MXene‑coated melamine foam and CNT/PVDF nanofiber membrane, it delivers ultra‑high pressure sensitivity of 986.51 kPa⁻¹ across 0–200 kPa and temperature sensitivity of...
Researchers introduced a succinonitrile (SN) coating on Li₅FeO₄ (LFO) particles, creating an air‑stable prelithiation additive (LFO@SN). The SN layer suppresses surface alkalization, preserving a high initial charge capacity of 623.8 mAh g⁻¹ after one hour of ambient exposure. In electrolyte, the coating...
The review surveys porous‑framework‑based triplet‑triplet annihilation upconversion (TTA‑UC) materials, emphasizing metal‑organic frameworks (MOFs) and porous aromatic frameworks (PAFs). It explains how these scaffolds improve oxygen resistance and enable solid‑state upconversion. The article details structure‑performance relationships, recent efficiency breakthroughs, and applications...
On March 20, 2026, the Moon will pass five degrees north of Venus, an alignment that coincides with the vernal equinox. While the conjunction occurs at 9 A.M. EDT, the two bodies become visible together in the evening sky, with Venus shining at...
Researchers Yuan Qiao and Ali Reza Kamali introduced a green, scalable polyimide binder modified with terephthalic acid for silicon anodes in lithium‑ion batteries. The binder reinforces electrode integrity, accelerates lithium‑ion kinetics, and boosts both capacity and long‑term cycling stability. Full‑cell...
Researchers used machine‑learning potentials and density‑functional theory to evaluate six dopants—Mg2+, Al3+, Ti4+, Zr4+, Nb5+ and Mo6+—in the P2‑type, cobalt‑free Na0.67Ni0.33Mn0.67O2 (NNMO) cathode. The study shows that high‑valence dopants (Zr, Nb, Mo) mainly reinforce bulk structural stability while preserving energy...

Researchers from the University of East Anglia and NHS Norfolk and Suffolk examined 5,057 social‑media posts and found high rates of misinformation about ADHD and autism, especially on TikTok. The study reported 52% of ADHD‑related TikTok videos and 41% of...
Fractional flow reserve (FFR) provides a more precise physiological assessment of coronary lesions than angiography alone, and its wire‑based use has improved PCI outcomes. Angiography‑derived FFR extends this functional insight without pressure wires, showing strong correlation with invasive measurements. In...
High fluid intake remains the cornerstone for preventing kidney stones, yet patient adherence is consistently low. Systematic reviews and a recent 2026 randomized trial confirm that adequate hydration reduces stone recurrence, but practical, behavioral, and environmental barriers limit real‑world effectiveness....
2026 could be a watershed year for obesity treatment as GLP‑1 receptor agonists cement their role after a decade of clinical success. The global market for weight‑loss drugs is forecast to hit US$150 billion by 2035, reflecting soaring demand. More than...

A two‑year analysis of 656 overweight adults aged 55‑75 in the PREDIMED‑Plus trial found that participants who regularly consumed virgin olive oil exhibited better preservation of cognitive function and greater gut‑microbiome diversity than those who used refined olive oil. The...

A two‑year pilot trial published in JAMA Neurology found that low‑dose oral lithium (150‑300 mg daily) slowed verbal memory decline in older adults with mild cognitive impairment. The neuroprotective benefit was most pronounced in participants who tested positive for amyloid‑beta, a...

The National Institutes of Health announced a $150 million investment in the new Complement‑ARIE program to develop and standardize human‑focused research tools, known as new approach methodologies (NAMs). The initiative will fund technology development centers, a data hub, and a validation...
A consortium of astronomers has announced the identification of 45 Earth‑like exoplanets that reside within the habitable zones of their host stars. The planets were selected from data gathered by space‑based missions such as Kepler, TESS, and ground‑based surveys, focusing...
Researchers from Denmark and collaborators reported that the hormone GDF15, known for causing nausea in early pregnancy, appears to rise in response to chronic alcohol consumption and may act as a feedback signal limiting intake. Small human studies at Oktoberfest...
Researchers from UCLA, Stanford, Utah, and Columbia have engineered T cell receptors to strengthen catch‑bond interactions with prostate cancer antigens, improving cytotoxic function. By altering just one or two amino acids in the TCR, the modified cells exhibit longer bond...

Physicists are nearing the first functional nuclear clock, which would keep time by measuring energy transitions in the nucleus of thorium‑229. A 2024 experiment finally pinpointed the elusive nuclear transition, unlocking the key to the device. Researchers worldwide are now...

Scientists at University College London have engineered bio‑grown oesophageal segments using patient‑derived stem cells and implanted them into minipigs, restoring normal swallowing. The grafts were seeded onto decellularized scaffolds, covered with a biodegradable mesh, and integrated functional muscle, nerves, and...