Science News and Headlines

Did We Just See a Primordial Black Hole at the Milky Way’s Edge?
NewsJun 4, 2026

Did We Just See a Primordial Black Hole at the Milky Way’s Edge?

Researchers at Swinburne University claim to have observed a primordial black hole, dubbed “Phoebe,” with a mass about three times that of Earth’s Moon, using microlensing of a star in the Large Magellanic Cloud captured by the Dark Energy Camera....

By Scientific American – Mind
More Conversations, Complex Questions, and Bold Ideas in Season Five of ‘The Joy of Why’
NewsJun 4, 2026

More Conversations, Complex Questions, and Bold Ideas in Season Five of ‘The Joy of Why’

Quanta Magazine’s *The Joy of Why* returns for its fifth season with 12 brand‑new episodes that dive into the most provocative questions in basic science and mathematics. Hosts Steven Strogatz and Janna Levin open the season on June 11 with Nobel...

By Quanta Magazine
New Research Indicates Sounds You Can’t Hear Can Spike Your Cortisol Levels, Offering a Biological Reason for Sudden Creepy Feelings
NewsJun 4, 2026

New Research Indicates Sounds You Can’t Hear Can Spike Your Cortisol Levels, Offering a Biological Reason for Sudden Creepy Feelings

A new study published in Frontiers in Behavioral Neuroscience shows that exposure to inaudible low‑frequency sound—specifically an 18 Hz tone—triggers a measurable rise in salivary cortisol and negative mood ratings. Thirty‑five university participants were split into groups listening to calming or...

By PsyPost
A Rainbow Patchwork Quilt Shows Agriculture From Space | Space Photo of the Day for June 4, 2026
NewsJun 4, 2026

A Rainbow Patchwork Quilt Shows Agriculture From Space | Space Photo of the Day for June 4, 2026

NASA’s NISAR satellite, a joint NASA‑ISRO radar mission launched on July 28 2025, has produced a vivid composite image of South Africa’s agricultural heartland. The radar data are rendered in color‑coded blocks that differentiate vegetation, bare soil and seasonal change, highlighting the...

By Space.com
Black Hole Wind Emerges After 50-Year Search
NewsJun 4, 2026

Black Hole Wind Emerges After 50-Year Search

After five years of ALMA observations, Northwestern astronomers have identified a hot wind blowing from the Milky Way’s central supermassive black hole, Sagittarius A*. The wind carved a three‑light‑year cone‑shaped cavity in surrounding cold molecular gas, a feature that aligns with...

By Courthouse News Service
Laser 'Origami' Could Help Astronauts Build Structures on the Moon
NewsJun 4, 2026

Laser 'Origami' Could Help Astronauts Build Structures on the Moon

University of Florida researchers have demonstrated laser‑forming, or “laser origami,” that can bend lunar‑regolith glass without physical contact, paving the way for on‑site construction on the Moon. By adjusting power from 50 W to 40 W and increasing scan speed, they kept...

By Phys.org - Space News
STAT+: AI Titans Push Congress for DNA Safeguards
NewsJun 4, 2026

STAT+: AI Titans Push Congress for DNA Safeguards

AI pioneers are pressing Congress to adopt robust DNA data safeguards amid growing concerns over genetic privacy. At the same time, transformer co‑creator Jakob Uszkoreit has launched Inceptive Nucleics, a startup that applies foundation‑model AI to RNA‑based therapeutics such as...

By STAT (Biotech)
B12, Folate Supplements May Be Key to Tackling Chronic Fatigue
NewsJun 4, 2026

B12, Folate Supplements May Be Key to Tackling Chronic Fatigue

Researchers at Osaka University analyzed data from 2,618 adults and found that elevated blood homocysteine—a marker of vitamin B12 and folate deficiency—was associated with higher physical fatigue in men and lower motivation in women. The cross‑sectional study, published in Nutrients,...

By Medical News Today
A Blip on a Telescope in a Colorado Parking Lot Bolstered a Space Mission That Has Found Thousands of Planets...
NewsJun 4, 2026

A Blip on a Telescope in a Colorado Parking Lot Bolstered a Space Mission That Has Found Thousands of Planets...

In 1999 a Harvard graduate student, David Charbonneau, used a modest four‑inch telescope in a Colorado parking lot to capture the first photometric transit of an exoplanet around star HD 209458. The clear 1 percent dip proved that the transit method could...

By Smithsonian Magazine (Science & Nature)
Effects of Using Solar Daylighting to Offset LED Lighting in Vertical Farming
NewsJun 4, 2026

Effects of Using Solar Daylighting to Offset LED Lighting in Vertical Farming

A 2026 study examined roof‑mounted light‑pipe daylighting in a three‑tier vertical farm in Dubai. Ray‑tracing showed optical efficiencies of 45%–75%, while hybrid daylight‑LED strategies kept yields and cut specific electricity use to 6.32 kWh kg⁻¹, a 14% improvement over full LED operation....

By Vertical Farm Daily
Researchers Claim Printed Yeast Gel Could Replace Plaster and Plastic
NewsJun 4, 2026

Researchers Claim Printed Yeast Gel Could Replace Plaster and Plastic

Swedish researchers at Chalmers University have developed a printable bio‑based gel made from baker’s yeast, wood‑derived cellulose, algal alginate, plant glycerol and water. The hydrogel can be extruded at room temperature without heating or support structures, producing complex architectural elements...

By Global Construction Review
Humans Are Changing How Nature Smells, With Risks for Wildlife
NewsJun 4, 2026

Humans Are Changing How Nature Smells, With Risks for Wildlife

Human activities—from air pollution to fertilizers and fungicides—are reshaping the planet’s “smellscapes,” degrading the volatile organic compounds that many species rely on for communication. Laboratory and field studies show that ozone and nitrogen oxides break down floral scents, cutting bee...

By Yale Environment 360
The Location of Your Body Fat Is Linked to How Fast Your Brain Ages
NewsJun 4, 2026

The Location of Your Body Fat Is Linked to How Fast Your Brain Ages

Body‑mass index has long been the default yardstick for obesity, yet it masks the heterogeneous behavior of fat stored in different body compartments. A new Nature Mental Health study of over 18,000 UK Biobank participants (average age 62) used DXA...

By PsyPost
When the Fear of Polio Gripped the World, Jonas Salk’s Determination Led to a Liberating Medical Breakthrough
NewsJun 4, 2026

When the Fear of Polio Gripped the World, Jonas Salk’s Determination Led to a Liberating Medical Breakthrough

In the early 1950s, Jonas Salk pioneered an inactivated‑virus polio vaccine that defied prevailing belief that only live viruses could confer immunity. After successful animal work, his team launched a massive 1.8 million‑child field trial in 1954, employing double‑blind and observational...

By Smithsonian Magazine – Innovation
Plant‐Derived Thylakoids Potentiate Copper‐Mediated Multimodal Cell Death via Hypoxia Alleviation for Synergistic Antitumor Therapy
NewsJun 4, 2026

Plant‐Derived Thylakoids Potentiate Copper‐Mediated Multimodal Cell Death via Hypoxia Alleviation for Synergistic Antitumor Therapy

Researchers have unveiled TC@UN/G, a hybrid drug‑release platform that merges copper‑loaded metal‑organic frameworks, photosynthetic plant thylakoids, and a thermosensitive F127 hydrogel. Upon peritumoral injection and light exposure, thylakoids produce oxygen, mitigating tumor hypoxia and restoring mitochondrial activity. This oxygenation sensitizes...

By Small (Wiley)
A Biomimetic Bidirectional Interphase Enabled by a Single Molecule for Ultra‐Stable Zn‐I2 Batteries
NewsJun 4, 2026

A Biomimetic Bidirectional Interphase Enabled by a Single Molecule for Ultra‐Stable Zn‐I2 Batteries

Researchers introduced sodium camphorsulfonate (SCS) as a single‑molecule, bidirectional electrolyte additive for zinc‑iodine (Zn‑I2) batteries. The additive orients Zn deposition on the (002) plane, curtails hydrogen evolution, and simultaneously anchors polyiodides to stop shuttle at the I2 cathode. This dual...

By Small (Wiley)
Gas Adsorption‐Driven Electronic Modulation in WO3@Cu3(HHTP)2 Heterostructure: Mechanistic Origin of Selective Drift Resistance Room‐Temperature Formaldehyde Sensing
NewsJun 4, 2026

Gas Adsorption‐Driven Electronic Modulation in WO3@Cu3(HHTP)2 Heterostructure: Mechanistic Origin of Selective Drift Resistance Room‐Temperature Formaldehyde Sensing

Researchers engineered a WO3@Cu3(HHTP)2 heterostructure that combines a metal‑oxide nanograin with a conductive 2D metal‑organic framework to achieve ultra‑sensitive formaldehyde detection at room temperature. Interfacial orbital hybridization between W 5d and O 2p π‑orbitals modulates the electronic structure, causing a Fermi‑level shift...

By Small (Wiley)
Ru‐Doping‐Induced Dual‐Functionality in La0.6Sr0.4Co0.2Fe0.8O3‐δ: Enhancing Efficient Multi‐Fuels Oxidation and Suppressing Sr Segregation for Robust Symmetric Solid Oxide Cells
NewsJun 4, 2026

Ru‐Doping‐Induced Dual‐Functionality in La0.6Sr0.4Co0.2Fe0.8O3‐δ: Enhancing Efficient Multi‐Fuels Oxidation and Suppressing Sr Segregation for Robust Symmetric Solid Oxide Cells

Researchers introduced a Ru‑doped, A‑site‑deficient perovskite (La0.6Sr0.4)0.9Ru0.1Co0.2Fe0.8O3‑δ, termed LSRCF, as a symmetric electrode for solid‑oxide cells. Under reducing conditions the material exsolves CoFeRu nano‑alloys that create active metal/oxide interfaces, accelerating oxidation of H₂, CH₄ and C₃H₈. In oxidizing mode Ru...

By Small (Wiley)
Rechargeable Na‐Seawater Batteries—A Promising Battery Energy Storage Solution for Coastal Economies
NewsJun 4, 2026

Rechargeable Na‐Seawater Batteries—A Promising Battery Energy Storage Solution for Coastal Economies

A new review highlights rechargeable sodium‑seawater batteries (SWBs) as a high‑energy‑density alternative for battery energy storage systems, especially in coastal regions. The authors report volumetric energy densities exceeding 4 kWh per liter—about five times that of hydrogen‑based storage—and outline how seawater...

By Small (Wiley)
Could Gut Parasites Be Influencing Your Behaviour?
NewsJun 4, 2026

Could Gut Parasites Be Influencing Your Behaviour?

Recent interdisciplinary studies are reviving the hypothesis that gut parasites can subtly steer human behaviour. Researchers have documented correlations between Toxoplasma gondii exposure and altered risk‑taking, as well as links to mood disorders such as depression and schizophrenia. Experimental work...

By BBC News – Health
Mammalian Osteoderm Ultrastructure in the Armored Acomys Spiny Mouse Tail
NewsJun 4, 2026

Mammalian Osteoderm Ultrastructure in the Armored Acomys Spiny Mouse Tail

Researchers used 2D and 3D microscopy to map the ultrastructure of osteoderms—calcified armor plates—in the tail skin of the spiny mouse (Acomys cahirinus). The plates consist of calcium‑phosphate biomineral with bone‑like and tooth‑like features arranged in a periodic A‑B pattern...

By Small (Wiley)
Photoexcitation Flips 2D Moiré Devices From Metals to Insulators in Ultrafast Test
NewsJun 4, 2026

Photoexcitation Flips 2D Moiré Devices From Metals to Insulators in Ultrafast Test

Researchers at Columbia University and UC Riverside demonstrated an ultrafast photo‑induced metal‑to‑insulator transition in 2D moiré heterostructures made of WS₂/WSe₂ with graphite gates. Using femtosecond laser pulses they first doped the devices metallic, then triggered a rapid transition to a...

By Phys.org (Quantum Physics News)
Detection at the Nanoscale: A Phosphate-Detecting Electrochemical Sensor
NewsJun 4, 2026

Detection at the Nanoscale: A Phosphate-Detecting Electrochemical Sensor

Researchers at Kansas State University have patented a printed graphene electrochemical sensor that detects phosphate molecules in water. The device uses a thin graphene nano‑ink layer to generate a voltage signal proportional to phosphate concentration, enabling integration with digital data...

By Phys.org – Nanotechnology
Scientists Just Discovered that PMOS May Develop Years Before Originally Thought
NewsJun 4, 2026

Scientists Just Discovered that PMOS May Develop Years Before Originally Thought

A new study of 322 mother‑daughter pairs found that higher prenatal exposure to specific per‑ and polyfluoroalkyl substances (PFAS) is linked to an increased risk of polyendocrine metabolic ovarian syndrome (PMOS) in teenage daughters. Mothers with elevated EtFOSAA levels were...

By Womens Health
Solidion Technology Announces Patented Extreme-Climate Battery Technology Targeting Aerospace and AI Applications
NewsJun 4, 2026

Solidion Technology Announces Patented Extreme-Climate Battery Technology Targeting Aerospace and AI Applications

Solidion Technology unveiled its patented Generation Extreme‑Climate Battery (Gen‑ECB), a graphene‑based power solution that operates reliably from –80 °C to +60 °C. The platform combines active thermal regulation with solid‑state chemistries delivering over 380 Wh/kg, targeting satellites, low‑Earth‑orbit AI data centers, crewed spacecraft,...

By Graphene-Info
Humans Conquered the Planet 300 Times Faster than Genetic Evolution Can Explain
NewsJun 4, 2026

Humans Conquered the Planet 300 Times Faster than Genetic Evolution Can Explain

Humans have colonized the planet in roughly 300,000 years, a pace far beyond what genetic evolution alone would allow. A new PNAS study by Charles Perreault quantifies this advantage, estimating that without cultural transmission it would have taken about 88 million...

By Scientific American – Mind
Want Faster Reflexes & Better Balance? This Habit Sharpens Brain-Body Connection
NewsJun 4, 2026

Want Faster Reflexes & Better Balance? This Habit Sharpens Brain-Body Connection

A recent study in *Medicine & Science in Sports & Exercise* found that just four weeks of hand‑grip resistance training, performed three times a week, significantly increased nerve conduction velocity in participants aged 18 to 84. Both younger and older...

By Mindbodygreen
Alnylam Hops on AI Train with up to $2B Inceptive Partnership
NewsJun 4, 2026

Alnylam Hops on AI Train with up to $2B Inceptive Partnership

Alnylam Pharmaceuticals has struck a partnership with Inceptive Nucleics, committing $30 million upfront for access to the firm’s generative‑AI platform, with the agreement capable of reaching $2 billion in value through preclinical, regulatory and commercial milestones. Inceptive’s model learns disease biology and...

By BioSpace
[Comment] Endothelin Antagonism in IgA Nephropathy: Promise Ahead of Proof?
NewsJun 4, 2026

[Comment] Endothelin Antagonism in IgA Nephropathy: Promise Ahead of Proof?

A recent Lancet commentary evaluates endothelin‑A receptor antagonists (ERAs) as a therapeutic avenue for IgA nephropathy, citing mechanistic data that link intrarenal endothelin‑1 over‑expression to inflammation, fibrosis, and nephron loss. The authors highlight the ALIGN phase‑3 trial, where atrasentan modestly...

By The Lancet (Current)
AI Can Now Coach Amateur Virologists, and Top Tech Leaders Want Congress to Act on DNA Security
NewsJun 4, 2026

AI Can Now Coach Amateur Virologists, and Top Tech Leaders Want Congress to Act on DNA Security

In an open letter, leading technology CEOs and prominent scientists urged Congress to mandate federal screening of all synthetic DNA orders. They highlight that AI tools now answer virology lab‑procedure questions better than PhD‑level experts, lowering barriers for malicious actors....

By THE DECODER
Scientists Found a Split-Second Shortcut Your Brain Takes when Reading Numbers
NewsJun 4, 2026

Scientists Found a Split-Second Shortcut Your Brain Takes when Reading Numbers

Researchers at Ariel University recorded brain activity while participants viewed multi‑digit numbers that were visually equalized in size. The EEG data revealed a distinct neural response to the physical length of a number as early as 120‑150 ms after it appeared,...

By PsyPost
Heat Pumps Shown to Slash Emissions and Energy Use in Future Homes
NewsJun 4, 2026

Heat Pumps Shown to Slash Emissions and Energy Use in Future Homes

New research by Bellway and the University of Salford shows air‑source heat pumps can achieve more than four times the efficiency of conventional gas boilers in new‑build homes. Tests in the Energy House 2.0 climate chamber recorded a coefficient of performance...

By Energy Live News
Search for Alien Technology on Interstellar Comet 3I/ATLAS Comes up Empty
NewsJun 4, 2026

Search for Alien Technology on Interstellar Comet 3I/ATLAS Comes up Empty

Astronomers used the Allen Telescope Array to search for technosignatures from interstellar comet 3I/ATLAS, discovered in July 2025 traveling 137,000 mi/h. The comet’s composition—methanol and frozen CO₂—pointed to a natural origin. After several hours of full‑band observations, no narrow‑band radio signals were...

By Scientific American – Mind
This Everyday Habit May May Slow “Metabolic Aging,” Study Suggests
NewsJun 4, 2026

This Everyday Habit May May Slow “Metabolic Aging,” Study Suggests

A new analysis of NHANES data and a Chinese cohort links overall diet quality to healthier metabolic aging markers. Participants with higher Healthy Eating Index‑2015 scores showed lower insulin resistance (HOMA‑IR) and more favorable lipid profiles (AIP). The study also...

By Mindbodygreen
Stonehenge's Altar Stone Probably Wasn't Transported by a Glacier
NewsJun 4, 2026

Stonehenge's Altar Stone Probably Wasn't Transported by a Glacier

Researchers have chemically matched Stonehenge’s 6‑tonne altar stone to sandstone outcrops in northeast Scotland, confirming a 750‑kilometre journey. While an ice‑flow scenario could have dropped the monolith at Dogger Bank, the timing and required conditions make human transport far more...

By New Scientist – Robots
ORNL Reveals New High-Temp Additive Manufacturing Aluminium Alloy
NewsJun 4, 2026

ORNL Reveals New High-Temp Additive Manufacturing Aluminium Alloy

Oak Ridge National Laboratory unveiled DuAlumin-3D, a high‑temperature, 3‑D‑printable aluminium alloy that retains strength up to 400 °C—about 100 °C hotter than conventional aluminium grades. The alloy blends aluminium with cerium, nickel and zirconium, delivering half the weight of titanium, roughly six...

By TCT Magazine
Opinion: Grail’s Multi-Cancer Early Detection Trial Was Negative. But as an Oncologist, I See More to This Story
NewsJun 4, 2026

Opinion: Grail’s Multi-Cancer Early Detection Trial Was Negative. But as an Oncologist, I See More to This Story

Grail’s Galleri multi‑cancer early‑detection (MCED) test was evaluated in the first randomized trial of its kind, involving 143,000 NHS participants aged 50‑77. Over three annual screenings, the study compared usual care to Galleri testing, with the primary endpoint being a...

By STAT (Biotech)
NASA Begins Testing Lunar Wastewater Processing Station
NewsJun 4, 2026

NASA Begins Testing Lunar Wastewater Processing Station

NASA has shipped its Divergent Deployable Wastewater Treatment Facility from Kennedy Space Center to the University of North Dakota for hands‑on testing. Graduate students will connect the mobile plant to the university’s Integrated Lunar/Martian Analog Habitat, simulating off‑world conditions. The...

By Orbital Today
ExoMars Rover Targets Vast Bed of Clay in Search for Life
NewsJun 4, 2026

ExoMars Rover Targets Vast Bed of Clay in Search for Life

A new study shows that clay deposits stretch roughly 600 km from Oxia Planum to Mawrth Vallis, suggesting a regional or possibly global water event on early Mars. The clays at Oxia Planum date to about four billion years ago, predating those at Mawrth Vallis, and...

By European Space Agency News
Revolutionizing Deep Space Exploration with AI and Machine Learning
NewsJun 4, 2026

Revolutionizing Deep Space Exploration with AI and Machine Learning

Artificial intelligence and machine learning are reshaping deep‑space missions, with the AI‑in‑space market projected to rise from $5.9 billion in 2025 to $7.8 billion in 2026, a 32.3% CAGR. NASA has embedded AI into its Mars rovers—Curiosity and Perseverance—enabling autonomous navigation, target...

By Telecom Review
This Cosmic Map of Magnetic Fields Could Help Illuminate One of the Universe’s Most Mysterious Forces
NewsJun 4, 2026

This Cosmic Map of Magnetic Fields Could Help Illuminate One of the Universe’s Most Mysterious Forces

An international team led by Australia’s CSIRO has released the largest ever map of cosmic magnetic fields, named SPICE_RACS, based on polarization data from nearly 4 million galaxies observed with the ASKAP radio telescope. The dataset is five times larger and...

By The Guardian - Space
Chinese Robot Helps Children with Nerve Disorder Stand up for the First Time
NewsJun 4, 2026

Chinese Robot Helps Children with Nerve Disorder Stand up for the First Time

Researchers from Beihang University, Peking University Third Hospital and MIT have demonstrated that a lightweight, resistive knee‑wearable robot can help children with spinal muscular atrophy (SMA) regain the ability to stand. In a six‑week study, six Chinese children aged six...

By South China Morning Post — Economy
Legend’s Ex Vivo Design Expertise Underpins in Vivo CAR T Efficacy
NewsJun 4, 2026

Legend’s Ex Vivo Design Expertise Underpins in Vivo CAR T Efficacy

Legend announced its first‑in‑human in vivo CAR T trial, reporting response rates that rival traditional ex vivo cell therapies. The company leveraged design principles from its successful ex vivo platform to engineer dual‑targeted, high‑affinity T‑cells that can be dosed directly in patients. While...

By BioCentury
Cellulose Nanofibril Binder Helps Build Cleaner, Higher-Capacity Lithium Batteries
NewsJun 4, 2026

Cellulose Nanofibril Binder Helps Build Cleaner, Higher-Capacity Lithium Batteries

Researchers reported a charge‑engineered cellulose nanofibril (c‑CNF) binder that replaces fluorinated PVDF and toxic NMP solvent in lithium‑ion battery electrodes. The c‑CNF binder forms a nanofibrous, hydrogen‑bonded network that improves slurry stability, mechanical integrity, and lithium‑ion transport. Using ethylene glycol...

By AZoNano
New Post-Liver Transplant Protocol Results in 0% Heavy Alcohol Relapse Rate
NewsJun 4, 2026

New Post-Liver Transplant Protocol Results in 0% Heavy Alcohol Relapse Rate

Mayo Clinic researchers introduced the Preventing Alcohol‑Related Complications after Transplant (PACT) protocol, a multidisciplinary post‑liver‑transplant treatment for alcohol‑use disorder. In a pilot study of 21 patients, the protocol achieved a 0 % heavy alcohol relapse rate within one year, compared with...

By Medical Xpress
NgR-Dependent Plasticity in a dCA3CaMKIIα → VTADA → NAc Circuit Underlies Stress Resilience and Susceptibility
NewsJun 4, 2026

NgR-Dependent Plasticity in a dCA3CaMKIIα → VTADA → NAc Circuit Underlies Stress Resilience and Susceptibility

The study demonstrates that chronic stress up‑regulates Nogo‑receptor (NgR) in dorsal CA3 (dCA3) glutamatergic neurons, and that NgR deletion in this region confers resilience to stress‑induced depressive‑like behaviors. NgR knockdown restores synaptic efficacy in the dCA3 → VTA dopamine → NAc circuit, while NgR...

By Nature (Biotechnology)
Gut Bacteria Regulate Intestinal Motor Circuits by Metabolizing Sex Hormones
NewsJun 4, 2026

Gut Bacteria Regulate Intestinal Motor Circuits by Metabolizing Sex Hormones

Researchers identified a subset of NOS1‑positive enteric neurons that express androgen receptors only when gut bacteria produce β‑glucuronidase, an enzyme that reactivates glucuronated androgens in the lumen. Experiments with germ‑free mice and GUS inhibitors showed that bacterial reactivation of androgens...

By Nature Neuroscience
This Mysterious Lung Disease Affects Millions of People — but a Drug Tested in Mice Shows Promise
NewsJun 4, 2026

This Mysterious Lung Disease Affects Millions of People — but a Drug Tested in Mice Shows Promise

Idiopathic pulmonary fibrosis (IPF), a fatal scarring disease affecting millions, currently has only two drugs that merely slow progression. Researchers at the National Institute of Environmental Health Sciences discovered that mice lacking the toll‑like receptor 5 (TLR5) develop more severe...

By Nature – Health Policy
Aberrant Tau Accumulation Caused by MAPT Mutations Induces Early Pathological Changes in Axonal Transport that Are Rescued by P38α Inhibition
NewsJun 4, 2026

Aberrant Tau Accumulation Caused by MAPT Mutations Induces Early Pathological Changes in Axonal Transport that Are Rescued by P38α Inhibition

Researchers used two‑photon imaging to track BDNF‑containing vesicles in live mouse brains and discovered that MAP MAPT mutations (P301S/P301L) disrupt axonal transport long before neurofibrillary tangles appear. The transport slowdown and increased pausing were reversed by acute inhibition of p38α/β kinases...

By Nature Neuroscience